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Items: 1 to 20 of 136

1.

A novel pleckstrin homology domain-containing protein enhances insulin-stimulated Akt phosphorylation and GLUT4 translocation in adipocytes.

Zhou QL, Jiang ZY, Mabardy AS, Del Campo CM, Lambright DG, Holik J, Fogarty KE, Straubhaar J, Nicoloro S, Chawla A, Czech MP.

J Biol Chem. 2010 Sep 3;285(36):27581-9. doi: 10.1074/jbc.M110.146886. Epub 2010 Jun 28.

2.

Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.

Tremblay F, Gagnon A, Veilleux A, Sorisky A, Marette A.

Endocrinology. 2005 Mar;146(3):1328-37. Epub 2004 Dec 2.

PMID:
15576463
3.

Postreceptoral adipocyte insulin resistance induced by nelfinavir is caused by insensitivity of PKB/Akt to phosphatidylinositol-3,4,5-trisphosphate.

Kachko I, Maissel A, Mazor L, Ben-Romano R, Watson RT, Hou JC, Pessin JE, Bashan N, Rudich A.

Endocrinology. 2009 Jun;150(6):2618-26. doi: 10.1210/en.2008-1205. Epub 2009 Jan 29.

4.

Akt substrate TBC1D1 regulates GLUT1 expression through the mTOR pathway in 3T3-L1 adipocytes.

Zhou QL, Jiang ZY, Holik J, Chawla A, Hagan GN, Leszyk J, Czech MP.

Biochem J. 2008 May 1;411(3):647-55. doi: 10.1042/BJ20071084.

5.

Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.

Jiang ZY, Zhou QL, Holik J, Patel S, Leszyk J, Coleman K, Chouinard M, Czech MP.

J Biol Chem. 2005 Jun 3;280(22):21622-8. Epub 2005 Mar 30.

6.

Growth hormone inhibition of glucose uptake in adipocytes occurs without affecting GLUT4 translocation through an insulin receptor substrate-2-phosphatidylinositol 3-kinase-dependent pathway.

Sasaki-Suzuki N, Arai K, Ogata T, Kasahara K, Sakoda H, Chida K, Asano T, Pessin JE, Hakuno F, Takahashi S.

J Biol Chem. 2009 Mar 6;284(10):6061-70. doi: 10.1074/jbc.M808282200. Epub 2009 Jan 2.

7.

Impact of Src homology 2-containing inositol 5'-phosphatase 2 on the regulation of insulin signaling leading to protein synthesis in 3T3-L1 adipocytes cultured with excess amino acids.

Murakami S, Sasaoka T, Wada T, Fukui K, Nagira K, Ishihara H, Usui I, Kobayashi M.

Endocrinology. 2004 Jul;145(7):3215-23. Epub 2004 Mar 24.

PMID:
15044364
8.

Differential regulation of NHE1 phosphorylation and glucose uptake by inhibitors of the ERK pathway and p90RSK in 3T3-L1 adipocytes.

Chen S, Mackintosh C.

Cell Signal. 2009 Dec;21(12):1984-93. doi: 10.1016/j.cellsig.2009.09.009. Epub 2009 Sep 15.

9.

C2 domain-containing phosphoprotein CDP138 regulates GLUT4 insertion into the plasma membrane.

Xie X, Gong Z, Mansuy-Aubert V, Zhou QL, Tatulian SA, Sehrt D, Gnad F, Brill LM, Motamedchaboki K, Chen Y, Czech MP, Mann M, Krüger M, Jiang ZY.

Cell Metab. 2011 Sep 7;14(3):378-89. doi: 10.1016/j.cmet.2011.06.015.

10.

ArPIKfyve-PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytes.

Ikonomov OC, Sbrissa D, Dondapati R, Shisheva A.

Exp Cell Res. 2007 Jul 1;313(11):2404-16. Epub 2007 Mar 30.

11.

Chronic endothelin-1 treatment leads to heterologous desensitization of insulin signaling in 3T3-L1 adipocytes.

Ishibashi KI, Imamura T, Sharma PM, Huang J, Ugi S, Olefsky JM.

J Clin Invest. 2001 May;107(9):1193-202.

12.

Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake.

Green CJ, Göransson O, Kular GS, Leslie NR, Gray A, Alessi DR, Sakamoto K, Hundal HS.

J Biol Chem. 2008 Oct 10;283(41):27653-67. doi: 10.1074/jbc.M802623200. Epub 2008 Jul 31.

13.

Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes.

Kotani K, Ogawa W, Matsumoto M, Kitamura T, Sakaue H, Hino Y, Miyake K, Sano W, Akimoto K, Ohno S, Kasuga M.

Mol Cell Biol. 1998 Dec;18(12):6971-82.

15.

Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes.

Fasshauer M, Klein J, Ueki K, Kriauciunas KM, Benito M, White MF, Kahn CR.

J Biol Chem. 2000 Aug 18;275(33):25494-501.

16.

Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase-activating protein abundant in skeletal muscle, is partially relieved by AMP-activated protein kinase activation.

Chavez JA, Roach WG, Keller SR, Lane WS, Lienhard GE.

J Biol Chem. 2008 Apr 4;283(14):9187-95. doi: 10.1074/jbc.M708934200. Epub 2008 Feb 7.

17.
18.

The effects of intracellular calcium depletion on insulin signaling in 3T3-L1 adipocytes.

Worrall DS, Olefsky JM.

Mol Endocrinol. 2002 Feb;16(2):378-89.

PMID:
11818508
19.

PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes.

Tang X, Powelka AM, Soriano NA, Czech MP, Guilherme A.

J Biol Chem. 2005 Jun 10;280(23):22523-9. Epub 2005 Apr 11.

20.

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