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Amebic monocyte locomotion inhibitory factor peptide ameliorates inflammation in CIA mouse model by downregulation of cell adhesion, inflammation/chemotaxis, and matrix metalloproteinases genes.

Godina-Gonzalez S, Furuzawa-Carballeda J, Utrera-Barillas D, Alcocer-Varela J, Teran LM, Vazquez-del Mercado M, Leal YA, Alvarado-Cabrero I, Velazquez JR.

Inflamm Res. 2010 Dec;59(12):1041-51. doi: 10.1007/s00011-010-0224-2. Epub 2010 Jun 27.


The monocyte locomotion inhibitory factor an anti-inflammatory peptide; therapeutics originating from amebic abscess of the liver.

Velazquez JR.

Recent Pat Endocr Metab Immune Drug Discov. 2011 Jan;5(1):7-12. Review.


An amebic anti-inflammatory peptide down-regulates ex vivo IL-1β expression in patients with rheumatoid arthritis.

Velázquez JR, Garibay-Martínez L, Martínez-Tejada P, Leal YA.

Reumatol Clin. 2012 Nov-Dec;8(6):315-20. doi: 10.1016/j.reuma.2012.03.012. Epub 2012 Jun 30.


Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis.

Joosten LA, Lubberts E, Helsen MM, Saxne T, Coenen-de Roo CJ, Heinegård D, van den Berg WB.

Arthritis Res. 1999;1(1):81-91. Epub 1999 Oct 26.


Inhibitory effects of a traditional Chinese herbal formula TBL-II on type II collagen-induced arthritis in mice.

Shen X, Li C, Zhao H, Li S, Chen J, Kobayashi Y, Shen W.

J Ethnopharmacol. 2011 Mar 24;134(2):399-405. doi: 10.1016/j.jep.2010.12.033. Epub 2011 Jan 5.


Oleuropein aglycone, an olive oil compound, ameliorates development of arthritis caused by injection of collagen type II in mice.

Impellizzeri D, Esposito E, Mazzon E, Paterniti I, Di Paola R, Morittu VM, Procopio A, Britti D, Cuzzocrea S.

J Pharmacol Exp Ther. 2011 Dec;339(3):859-69. doi: 10.1124/jpet.111.182808. Epub 2011 Aug 31.


Brazilin isolated from Caesalpinia sappan L. inhibits rheumatoid arthritis activity in a type-II collagen induced arthritis mouse model.

Jung EG, Han KI, Hwang SG, Kwon HJ, Patnaik BB, Kim YH, Han MD.

BMC Complement Altern Med. 2015 Apr 22;15:124. doi: 10.1186/s12906-015-0648-x.


Robust Therapeutic Efficacy of Matrix Metalloproteinase-2-Cleavable Fas-1-RGD Peptide Complex in Chronic Inflammatory Arthritis.

Nam EJ, Kang JH, Sa KH, Sung S, Park JY, Jo DG, Park JH, Kim IS, Kang YM.

PLoS One. 2016 Oct 14;11(10):e0164102. doi: 10.1371/journal.pone.0164102. eCollection 2016.


Effects and mechanisms of total glucosides of paeony on joint damage in rat collagen-induced arthritis.

Zhu L, Wei W, Zheng YQ, Jia XY.

Inflamm Res. 2005 May;54(5):211-20.


Palmitoylethanolamide and luteolin ameliorate development of arthritis caused by injection of collagen type II in mice.

Impellizzeri D, Esposito E, Di Paola R, Ahmad A, Campolo M, Peli A, Morittu VM, Britti D, Cuzzocrea S.

Arthritis Res Ther. 2013;15(6):R192. Erratum in: Arthritis Res Ther. 2016;18(1):101.


Kinsenoside inhibits the inflammatory mediator release in a type-II collagen induced arthritis mouse model by regulating the T cells responses.

Hsiao HB, Hsieh CC, Wu JB, Lin H, Lin WC.

BMC Complement Altern Med. 2016 Feb 25;16:80. doi: 10.1186/s12906-016-1054-8.


Ethyl pyruvate therapy attenuates experimental severe arthritis caused by type II collagen (CII) in the mouse (CIA).

Di Paola R, Mazzon E, Galuppo M, Esposito E, Bramanti P, Fink MP, Cuzzocrea S.

Int J Immunopathol Pharmacol. 2010 Oct-Dec;23(4):1087-98.


Erythropoietin reduces the degree of arthritis caused by type II collagen in the mouse.

Cuzzocrea S, Mazzon E, di Paola R, Genovese T, Patel NS, Britti D, de Majo M, Caputi AP, Thiemermann C.

Arthritis Rheum. 2005 Mar;52(3):940-50.


Triptolide, a diterpenoid triepoxide, suppresses inflammation and cartilage destruction in collagen-induced arthritis mice.

Lin N, Liu C, Xiao C, Jia H, Imada K, Wu H, Ito A.

Biochem Pharmacol. 2007 Jan 1;73(1):136-46. Epub 2006 Sep 6.


META060 inhibits osteoclastogenesis and matrix metalloproteinases in vitro and reduces bone and cartilage degradation in a mouse model of rheumatoid arthritis.

Konda VR, Desai A, Darland G, Bland JS, Tripp ML.

Arthritis Rheum. 2010 Jun;62(6):1683-92. doi: 10.1002/art.27441.


Inhibition of connective tissue growth factor ameliorates disease in a murine model of rheumatoid arthritis.

Nozawa K, Fujishiro M, Kawasaki M, Yamaguchi A, Ikeda K, Morimoto S, Iwabuchi K, Yanagida M, Ichinose S, Morioka M, Ogawa H, Takamori K, Takasaki Y, Sekigawa I.

Arthritis Rheum. 2013 Jun;65(6):1477-86. doi: 10.1002/art.37902.


Torilin ameliorates type II collagen-induced arthritis in mouse model of rheumatoid arthritis.

Endale M, Lee WM, Kwak YS, Kim NM, Kim BK, Kim SH, Cho J, Kim S, Park SC, Yun BS, Ko D, Rhee M.

Int Immunopharmacol. 2013 Jun;16(2):232-42. doi: 10.1016/j.intimp.2013.04.012. Epub 2013 Apr 24.


Gallium nitrate ameliorates type II collagen-induced arthritis in mice.

Choi JH, Lee JH, Roh KH, Seo SK, Choi IW, Park SG, Lim JG, Lee WJ, Kim MH, Cho KR, Kim YJ.

Int Immunopharmacol. 2014 May;20(1):269-75. doi: 10.1016/j.intimp.2014.03.005. Epub 2014 Mar 19.


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