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Items: 1 to 20 of 81

1.

A 1,536-well ultra-high-throughput siRNA screen to identify regulators of the Wnt/beta-catenin pathway.

Chung N, Marine S, Smith EA, Liehr R, Smith ST, Locco L, Hudak E, Kreamer A, Rush A, Roberts B, Major MB, Moon RT, Arthur W, Cleary M, Strulovici B, Ferrer M.

Assay Drug Dev Technol. 2010 Jun;8(3):286-94. doi: 10.1089/adt.2009.0262.

PMID:
20578927
2.

New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening.

Major MB, Roberts BS, Berndt JD, Marine S, Anastas J, Chung N, Ferrer M, Yi X, Stoick-Cooper CL, von Haller PD, Kategaya L, Chien A, Angers S, MacCoss M, Cleary MA, Arthur WT, Moon RT.

Sci Signal. 2008 Nov 11;1(45):ra12. doi: 10.1126/scisignal.2000037.

3.

An efficient and fully automated high-throughput transfection method for genome-scale siRNA screens.

Chung N, Locco L, Huff KW, Bartz S, Linsley PS, Ferrer M, Strulovici B.

J Biomol Screen. 2008 Feb;13(2):142-8. doi: 10.1177/1087057107312032. Epub 2008 Jan 23.

PMID:
18216392
4.

[Effect of siRNA-mediated beta-catenin gene on Wnt signal pathway in lung adenocarcinoma A549 cell].

Teng Y, Wang XW, Wang YW, Wang J.

Zhonghua Yi Xue Za Zhi. 2010 Apr 13;90(14):988-92. Chinese.

PMID:
20646651
5.

beta-catenin siRNA regulation of apoptosis- and angiogenesis-related gene expression in hepatocellular carcinoma cells: potential uses for gene therapy.

Wang XH, Sun X, Meng XW, Lv ZW, Du YJ, Zhu Y, Chen J, Kong DX, Jin SZ.

Oncol Rep. 2010 Oct;24(4):1093-9.

PMID:
20811694
6.

Quantitative optimization of reverse transfection conditions for 384-well siRNA library screening.

LaPan P, Zhang J, Pan J, Haney S.

Assay Drug Dev Technol. 2008 Oct;6(5):683-91. doi: 10.1089/adt.2008.142.

PMID:
19035849
7.

Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor.

Dong YF, Soung do Y, Schwarz EM, O'Keefe RJ, Drissi H.

J Cell Physiol. 2006 Jul;208(1):77-86.

PMID:
16575901
8.

Cell-based assay for low- and high-scale screening of the Wnt/β-catenin signaling modulators.

Mazur M, Bujak A, Matloka M, Janowska S, Gunerka P, Bojarski L, Stanczak A, Klejman A, Bednarek A, Lamparska-Przybysz M, Wieczorek M.

Anal Biochem. 2015 Apr 15;475:56-67. doi: 10.1016/j.ab.2015.01.016. Epub 2015 Feb 7.

PMID:
25659657
9.

Designing, optimizing, and implementing high-throughput siRNA genomic screening with glioma cells for the discovery of survival genes and novel drug targets.

Thaker NG, McDonald PR, Zhang F, Kitchens CA, Shun TY, Pollack IF, Lazo JS.

J Neurosci Methods. 2010 Jan 15;185(2):204-12. doi: 10.1016/j.jneumeth.2009.09.023. Epub 2009 Sep 25.

PMID:
19782703
10.

Wnt/β-catenin signaling regulates MAPK and Akt1 expression and growth of hepatocellular carcinoma cells.

Wang XH, Meng XW, Sun X, Liu BR, Han MZ, DU YJ, Song YY, Xu W.

Neoplasma. 2011;58(3):239-44.

PMID:
21391741
11.

siRNA off-target effects in genome-wide screens identify signaling pathway members.

Buehler E, Khan AA, Marine S, Rajaram M, Bahl A, Burchard J, Ferrer M.

Sci Rep. 2012;2:428. doi: 10.1038/srep00428. Epub 2012 May 29.

12.

Epidermal growth factor receptor-directed enterocyte proliferation does not induce Wnt pathway transcription.

Taylor JA, Bernabe KQ, Guo J, Warner BW.

J Pediatr Surg. 2007 Jun;42(6):981-6.

PMID:
17560206
13.

Identification of genes regulated by Wnt/beta-catenin pathway and involved in apoptosis via microarray analysis.

Huang M, Wang Y, Sun D, Zhu H, Yin Y, Zhang W, Yang S, Quan L, Bai J, Wang S, Chen Q, Li S, Xu N.

BMC Cancer. 2006 Sep 7;6:221.

15.

Tumour cell migration in adamantinomatous craniopharyngiomas is promoted by activated Wnt-signalling.

Hölsken A, Buchfelder M, Fahlbusch R, Blümcke I, Buslei R.

Acta Neuropathol. 2010 May;119(5):631-9. doi: 10.1007/s00401-010-0642-9. Epub 2010 Feb 4.

PMID:
20131060
16.

Wnt/beta-catenin pathway deregulation in childhood adrenocortical tumors.

Leal LF, Mermejo LM, Ramalho LZ, Martinelli CE Jr, Yunes JA, Seidinger AL, Mastellaro MJ, Cardinalli IA, Brandalise SR, Moreira AC, Tone LG, Scrideli CA, Castro M, Antonini SR.

J Clin Endocrinol Metab. 2011 Oct;96(10):3106-14. doi: 10.1210/jc.2011-0363. Epub 2011 Aug 17.

PMID:
21849527
17.

Integrative analysis of genome-wide RNA interference screens.

Berndt JD, Biechele TL, Moon RT, Major MB.

Sci Signal. 2009 May 12;2(70):pt4. doi: 10.1126/scisignal.270pt4.

PMID:
19436058
18.

Nicotine-induced epithelial-mesenchymal transition via Wnt/β-catenin signaling in human airway epithelial cells.

Zou W, Zou Y, Zhao Z, Li B, Ran P.

Am J Physiol Lung Cell Mol Physiol. 2013 Feb 15;304(4):L199-209. doi: 10.1152/ajplung.00094.2012. Epub 2012 Nov 30.

19.

WNT/β-catenin pathway mediates the anti-adipogenic effect of platycodin D, a natural compound found in Platycodon grandiflorum.

Lee H, Bae S, Kim YS, Yoon Y.

Life Sci. 2011 Sep 12;89(11-12):388-94. doi: 10.1016/j.lfs.2011.07.006. Epub 2011 Jul 23.

PMID:
21798269
20.

Both ERK and Wnt/beta-catenin pathways are involved in Wnt3a-induced proliferation.

Yun MS, Kim SE, Jeon SH, Lee JS, Choi KY.

J Cell Sci. 2005 Jan 15;118(Pt 2):313-22. Epub 2004 Dec 22.

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