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Items: 1 to 20 of 82

1.

Altered dynamics of intestinal cell maturation in Apc1638N/+ mice.

Wang D, Pezo RC, Corner G, Sison C, Lesser ML, Shenoy SM, Mariadason JM, Singer RH, Augenlicht LH.

Cancer Res. 2010 Jul 1;70(13):5348-57. doi: 10.1158/0008-5472.CAN-09-4593. Epub 2010 Jun 22.

2.

Paneth cell marker expression in intestinal villi and colon crypts characterizes dietary induced risk for mouse sporadic intestinal cancer.

Wang D, Peregrina K, Dhima E, Lin EY, Mariadason JM, Augenlicht LH.

Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10272-7. doi: 10.1073/pnas.1017668108. Epub 2011 Jun 7.

3.

Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation.

Muñoz NM, Upton M, Rojas A, Washington MK, Lin L, Chytil A, Sozmen EG, Madison BB, Pozzi A, Moon RT, Moses HL, Grady WM.

Cancer Res. 2006 Oct 15;66(20):9837-44.

4.

A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts.

Leedham SJ, Rodenas-Cuadrado P, Howarth K, Lewis A, Mallappa S, Segditsas S, Davis H, Jeffery R, Rodriguez-Justo M, Keshav S, Travis SP, Graham TA, East J, Clark S, Tomlinson IP.

Gut. 2013 Jan;62(1):83-93. doi: 10.1136/gutjnl-2011-301601. Epub 2012 Jan 27.

5.

Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation.

Yang K, Popova NV, Yang WC, Lozonschi I, Tadesse S, Kent S, Bancroft L, Matise I, Cormier RT, Scherer SJ, Edelmann W, Lipkin M, Augenlicht L, Velcich A.

Cancer Res. 2008 Sep 15;68(18):7313-22. doi: 10.1158/0008-5472.CAN-08-0598.

6.

E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice.

Smits R, Ruiz P, Diaz-Cano S, Luz A, Jagmohan-Changur S, Breukel C, Birchmeier C, Birchmeier W, Fodde R.

Gastroenterology. 2000 Oct;119(4):1045-53.

PMID:
11040191
7.

Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine.

Andreu P, Colnot S, Godard C, Gad S, Chafey P, Niwa-Kawakita M, Laurent-Puig P, Kahn A, Robine S, Perret C, Romagnolo B.

Development. 2005 Mar;132(6):1443-51. Epub 2005 Feb 16.

8.

Cooperation between the thyroid hormone receptor TRalpha1 and the WNT pathway in the induction of intestinal tumorigenesis.

Kress E, Skah S, Sirakov M, Nadjar J, Gadot N, Scoazec JY, Samarut J, Plateroti M.

Gastroenterology. 2010 May;138(5):1863-74. doi: 10.1053/j.gastro.2010.01.041. Epub 2010 Jan 28.

PMID:
20114049
9.

Gene expression profiling of intestinal epithelial cell maturation along the crypt-villus axis.

Mariadason JM, Nicholas C, L'Italien KE, Zhuang M, Smartt HJ, Heerdt BG, Yang W, Corner GA, Wilson AJ, Klampfer L, Arango D, Augenlicht LH.

Gastroenterology. 2005 Apr;128(4):1081-8.

PMID:
15825089
10.

Stromal Indian hedgehog signaling is required for intestinal adenoma formation in mice.

Büller NV, Rosekrans SL, Metcalfe C, Heijmans J, van Dop WA, Fessler E, Jansen M, Ahn C, Vermeulen JL, Westendorp BF, Robanus-Maandag EC, Offerhaus GJ, Medema JP, D'Haens GR, Wildenberg ME, de Sauvage FJ, Muncan V, van den Brink GR.

Gastroenterology. 2015 Jan;148(1):170-180.e6. doi: 10.1053/j.gastro.2014.10.006. Epub 2014 Oct 13.

PMID:
25307863
11.

The intestinal epithelium and its neoplasms: genetic, cellular and tissue interactions.

Dove WF, Cormier RT, Gould KA, Halberg RB, Merritt AJ, Newton MA, Shoemaker AR.

Philos Trans R Soc Lond B Biol Sci. 1998 Jun 29;353(1370):915-23. Review.

12.

Aneuploidy arises at early stages of Apc-driven intestinal tumorigenesis and pinpoints conserved chromosomal loci of allelic imbalance between mouse and human.

Alberici P, de Pater E, Cardoso J, Bevelander M, Molenaar L, Jonkers J, Fodde R.

Am J Pathol. 2007 Jan;170(1):377-87.

13.

Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis.

Zeilstra J, Joosten SP, Dokter M, Verwiel E, Spaargaren M, Pals ST.

Cancer Res. 2008 May 15;68(10):3655-61. doi: 10.1158/0008-5472.CAN-07-2940.

14.

Intestinal and extra-intestinal tumor multiplicities in the Apc1638N mouse model after exposure to X-rays.

van der Houven van Oordt CW, Smits R, Williamson SL, Luz A, Khan PM, Fodde R, van der Eb AJ, Breuer ML.

Carcinogenesis. 1997 Nov;18(11):2197-203.

PMID:
9395221
15.

Role of c-Myc in intestinal tumorigenesis of the ApcMin/+ mouse.

Ignatenko NA, Holubec H, Besselsen DG, Blohm-Mangone KA, Padilla-Torres JL, Nagle RB, de Alboránç IM, Guillen-R JM, Gerner EW.

Cancer Biol Ther. 2006 Dec;5(12):1658-64. Epub 2006 Dec 7.

PMID:
17106247
16.

Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways.

Luo F, Brooks DG, Ye H, Hamoudi R, Poulogiannis G, Patek CE, Winton DJ, Arends MJ.

Int J Exp Pathol. 2009 Oct;90(5):558-74. doi: 10.1111/j.1365-2613.2009.00667.x.

17.

Intestinal epithelial cell-specific CD98 expression regulates tumorigenesis in Apc(Min/+) mice.

Nguyen HT, Dalmasso G, Yan Y, Laroui H, Charania M, Ingersoll S, Ayyadurai S, Zhang Y, Sitaraman S, Merlin D.

Lab Invest. 2012 Aug;92(8):1203-12. doi: 10.1038/labinvest.2012.83. Epub 2012 May 28.

18.

The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine.

Lin S, Lee SJ, Shim H, Chun J, Yun CC.

Am J Physiol Gastrointest Liver Physiol. 2010 Nov;299(5):G1128-38. doi: 10.1152/ajpgi.00321.2010. Epub 2010 Aug 19.

19.

Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice.

Segditsas S, Sieber O, Deheragoda M, East P, Rowan A, Jeffery R, Nye E, Clark S, Spencer-Dene B, Stamp G, Poulsom R, Suraweera N, Silver A, Ilyas M, Tomlinson I.

Hum Mol Genet. 2008 Dec 15;17(24):3864-75. doi: 10.1093/hmg/ddn286. Epub 2008 Sep 9.

20.

Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype.

Reed KR, Song F, Young MA, Hassan N, Antoine DJ, Gemici NB, Clarke AR, Jenkins JR.

Oncotarget. 2016 Aug 9;7(32):51665-51673. doi: 10.18632/oncotarget.10076.

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