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Items: 1 to 20 of 102

1.

Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds.

Vandebriel RJ, Pennings JL, Baken KA, Pronk TE, Boorsma A, Gottschalk R, Van Loveren H.

Toxicol Sci. 2010 Sep;117(1):81-9. doi: 10.1093/toxsci/kfq182. Epub 2010 Jun 20.

PMID:
20566472
2.

Upregulation of genes orchestrating keratinocyte differentiation, including the novel marker gene ID2, by contact sensitizers in human bulge-derived keratinocytes.

Yoshikawa Y, Sasahara Y, Kitano Y, Kanazawa N, Shima H, Hashimoto-Tamaoki T.

J Biochem Mol Toxicol. 2010 Jan-Feb;24(1):10-20. doi: 10.1002/jbt.20307.

PMID:
20146380
3.

Gene expression profiles and pathways in skin inflammation induced by three different sensitizers and an irritant.

Ku HO, Jeong SH, Kang HG, Pyo HM, Cho JH, Son SW, Yun SM, Ryu DY.

Toxicol Lett. 2009 Oct 28;190(2):231-7. doi: 10.1016/j.toxlet.2009.07.022. Epub 2009 Jul 30.

PMID:
19647056
4.

Gene expression studies in cultured dendritic cells: new indicators for the discrimination of skin sensitizers and irritants in vitro.

Szameit S, Vierlinger K, Farmer L, Tuschl H, Noehammer C.

Clin Exp Allergy. 2009 Jun;39(6):856-68. doi: 10.1111/j.1365-2222.2009.03222.x. Epub 2009 Mar 10.

PMID:
19302251
5.

Selective induction of cell-associated interleukin-1alpha in murine keratinocytes by chemical allergens.

Corsini E, Primavera A, Marinovich M, Galli CL.

Toxicology. 1998 Aug 21;129(2-3):193-200.

PMID:
9772097
6.

Further development of the NCTC 2544 IL-18 assay to identify in vitro contact allergens.

Galbiati V, Mitjans M, Lucchi L, Viviani B, Galli CL, Marinovich M, Corsini E.

Toxicol In Vitro. 2011 Apr;25(3):724-32. doi: 10.1016/j.tiv.2010.12.011. Epub 2010 Dec 21.

PMID:
21182927
7.

In vitro assessment of sensitizing activity of low molecular weight compounds.

Vandebriel RJ, Van Och FM, van Loveren H.

Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):142-8. Review.

PMID:
16000204
8.

Gene profiles of THP-1 macrophages after in vitro exposure to respiratory (non-)sensitizing chemicals: identification of discriminating genetic markers and pathway analysis.

Verstraelen S, Nelissen I, Hooyberghs J, Witters H, Schoeters G, Van Cauwenberge P, Van Den Heuvel R.

Toxicol In Vitro. 2009 Sep;23(6):1151-62. doi: 10.1016/j.tiv.2009.06.007. Epub 2009 Jun 13.

PMID:
19527780
9.

Gene profiles of a human bronchial epithelial cell line after in vitro exposure to respiratory (non-)sensitizing chemicals: identification of discriminating genetic markers and pathway analysis.

Verstraelen S, Nelissen I, Hooyberghs J, Witters H, Schoeters G, Van Cauwenberge P, Van Den Heuvel R.

Toxicology. 2009 Jan 31;255(3):151-9. doi: 10.1016/j.tox.2008.10.014. Epub 2008 Nov 6.

PMID:
19041681
10.
11.

Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens.

Corsini E, Mitjans M, Galbiati V, Lucchi L, Galli CL, Marinovich M.

Toxicol In Vitro. 2009 Aug;23(5):789-96. doi: 10.1016/j.tiv.2009.04.005. Epub 2009 May 4.

PMID:
19397996
12.

Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro.

Emter R, Ellis G, Natsch A.

Toxicol Appl Pharmacol. 2010 Jun 15;245(3):281-90. doi: 10.1016/j.taap.2010.03.009. Epub 2010 Mar 20.

PMID:
20307559
13.

Analysis of differential gene expression in auricular lymph nodes draining skin exposed to sensitizers and irritants.

Ku HO, Jeong SH, Kang HG, Pyo HM, Cho JH, Son SW, Ryu DY.

Toxicol Lett. 2008 Feb 28;177(1):1-9. doi: 10.1016/j.toxlet.2007.12.003. Epub 2008 Feb 1.

PMID:
18242016
14.

Microarray-based in vitro test system for the discrimination of contact allergens and irritants: identification of potential marker genes.

Szameit S, Vierlinger K, Farmer L, Tuschl H, Noehammer C.

Clin Chem. 2008 Mar;54(3):525-33. doi: 10.1373/clinchem.2007.097386. Epub 2008 Jan 17.

15.

Differential gene expression responses distinguish contact and respiratory sensitizers and nonsensitizing irritants in the local lymph node assay.

Adenuga D, Woolhiser MR, Gollapudi BB, Boverhof DR.

Toxicol Sci. 2012 Apr;126(2):413-25. doi: 10.1093/toxsci/kfs071. Epub 2012 Feb 2.

PMID:
22302311
16.

Microarray analyses in dendritic cells reveal potential biomarkers for chemical-induced skin sensitization.

Schoeters E, Verheyen GR, Nelissen I, Van Rompay AR, Hooyberghs J, Van Den Heuvel RL, Witters H, Schoeters GE, Van Tendeloo VF, Berneman ZN.

Mol Immunol. 2007 May;44(12):3222-33. Epub 2007 Mar 19.

PMID:
17374397
17.

Classification of sensitizing and irritative potential in a combined in-vitro assay.

Wanner R, Sonnenburg A, Quatchadze M, Schreiner M, Peiser M, Zuberbier T, Stahlmann R.

Toxicol Appl Pharmacol. 2010 Jun 1;245(2):211-8. doi: 10.1016/j.taap.2010.02.019. Epub 2010 Mar 8.

PMID:
20219181
18.

Differentiation of skin sensitizers from irritant chemicals by interleukin-1α and macrophage inflammatory protein-2 in murine keratinocytes.

Son D, Na Y, Cho WS, Lee BH, Heo Y, Park JH, Seok SH.

Toxicol Lett. 2013 Jan 10;216(1):65-71. doi: 10.1016/j.toxlet.2012.10.017. Epub 2012 Nov 22.

PMID:
23178550
19.

Applicability of a keratinocyte gene signature to predict skin sensitizing potential.

van der Veen JW, Pronk TE, van Loveren H, Ezendam J.

Toxicol In Vitro. 2013 Feb;27(1):314-22. doi: 10.1016/j.tiv.2012.08.023. Epub 2012 Aug 28.

PMID:
22935770
20.

Comparative DNA microarray analysis of human monocyte derived dendritic cells and MUTZ-3 cells exposed to the moderate skin sensitizer cinnamaldehyde.

Python F, Goebel C, Aeby P.

Toxicol Appl Pharmacol. 2009 Sep 15;239(3):273-83. doi: 10.1016/j.taap.2009.06.003. Epub 2009 Jun 12.

PMID:
19524605

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