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Items: 1 to 20 of 146

1.

TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus.

Guiducci C, Gong M, Xu Z, Gill M, Chaussabel D, Meeker T, Chan JH, Wright T, Punaro M, Bolland S, Soumelis V, Banchereau J, Coffman RL, Pascual V, Barrat FJ.

Nature. 2010 Jun 17;465(7300):937-41. doi: 10.1038/nature09102.

2.

Heat shock protein 90 associates with Toll-like receptors 7/9 and mediates self-nucleic acid recognition in SLE.

Saito K, Kukita K, Kutomi G, Okuya K, Asanuma H, Tabeya T, Naishiro Y, Yamamoto M, Takahashi H, Torigoe T, Nakai A, Shinomura Y, Hirata K, Sato N, Tamura Y.

Eur J Immunol. 2015 Jul;45(7):2028-41. doi: 10.1002/eji.201445293.

3.

Bruton's tyrosine kinase regulates TLR9 but not TLR7 signaling in human plasmacytoid dendritic cells.

Wang J, Lau KY, Jung J, Ravindran P, Barrat FJ.

Eur J Immunol. 2014 Apr;44(4):1130-6. doi: 10.1002/eji.201344030.

4.

TLR9/TLR7-triggered downregulation of BDCA2 expression on human plasmacytoid dendritic cells from healthy individuals and lupus patients.

Wu P, Wu J, Liu S, Han X, Lu J, Shi Y, Wang J, Lu L, Cao X.

Clin Immunol. 2008 Oct;129(1):40-8. doi: 10.1016/j.clim.2008.06.004.

PMID:
18684674
5.

U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7.

Savarese E, Chae OW, Trowitzsch S, Weber G, Kastner B, Akira S, Wagner H, Schmid RM, Bauer S, Krug A.

Blood. 2006 Apr 15;107(8):3229-34. Erratum in: Blood. 2006 May 15;107(10):3831.

6.

Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus.

Barrat FJ, Meeker T, Gregorio J, Chan JH, Uematsu S, Akira S, Chang B, Duramad O, Coffman RL.

J Exp Med. 2005 Oct 17;202(8):1131-9.

7.

Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9.

Guiducci C, Tripodo C, Gong M, Sangaletti S, Colombo MP, Coffman RL, Barrat FJ.

J Exp Med. 2010 Dec 20;207(13):2931-42. doi: 10.1084/jem.20101048.

8.

Activation of NF-κB via endosomal Toll-like receptor 7 (TLR7) or TLR9 suppresses murine herpesvirus 68 reactivation.

Haas F, Yamauchi K, Murat M, Bernasconi M, Yamanaka N, Speck RF, Nadal D.

J Virol. 2014 Sep 1;88(17):10002-12. doi: 10.1128/JVI.01486-14.

9.

B cell autophagy mediates TLR7-dependent autoimmunity and inflammation.

Weindel CG, Richey LJ, Bolland S, Mehta AJ, Kearney JF, Huber BT.

Autophagy. 2015;11(7):1010-24. doi: 10.1080/15548627.2015.1052206.

10.

PTPN22 Variant R620W Is Associated With Reduced Toll-like Receptor 7-Induced Type I Interferon in Systemic Lupus Erythematosus.

Wang Y, Ewart D, Crabtree JN, Yamamoto A, Baechler EC, Fazeli P, Peterson EJ.

Arthritis Rheumatol. 2015 Sep;67(9):2403-14. doi: 10.1002/art.39211.

11.

Distinct autoantibody profiles in systemic lupus erythematosus patients are selectively associated with TLR7 and TLR9 upregulation.

Chauhan SK, Singh VV, Rai R, Rai M, Rai G.

J Clin Immunol. 2013 Jul;33(5):954-64. doi: 10.1007/s10875-013-9887-0.

PMID:
23564191
12.

MicroRNA-146a regulates survival and maturation of human plasmacytoid dendritic cells.

Karrich JJ, Jachimowski LC, Libouban M, Iyer A, Brandwijk K, Taanman-Kueter EW, Nagasawa M, de Jong EC, Uittenbogaart CH, Blom B.

Blood. 2013 Oct 24;122(17):3001-9. doi: 10.1182/blood-2012-12-475087.

13.

Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus.

Thibault DL, Graham KL, Lee LY, Balboni I, Hertzog PJ, Utz PJ.

Arthritis Res Ther. 2009;11(4):R112. doi: 10.1186/ar2771.

14.

Role of nucleic acid-sensing TLRs in diverse autoantibody specificities and anti-nuclear antibody-producing B cells.

Koh YT, Scatizzi JC, Gahan JD, Lawson BR, Baccala R, Pollard KM, Beutler BA, Theofilopoulos AN, Kono DH.

J Immunol. 2013 May 15;190(10):4982-90. doi: 10.4049/jimmunol.1202986.

15.

Essential role for IKKβ in production of type 1 interferons by plasmacytoid dendritic cells.

Pauls E, Shpiro N, Peggie M, Young ER, Sorcek RJ, Tan L, Choi HG, Cohen P.

J Biol Chem. 2012 Jun 1;287(23):19216-28. doi: 10.1074/jbc.M112.345405.

16.

C-reactive protein inhibits plasmacytoid dendritic cell interferon responses to autoantibody immune complexes.

Mold C, Clos TW.

Arthritis Rheum. 2013 Jul;65(7):1891-901. doi: 10.1002/art.37968.

17.

Bcl-2 antagonists kill plasmacytoid dendritic cells from lupus-prone mice and dampen interferon-α production.

Zhan Y, Carrington EM, Ko HJ, Vikstrom IB, Oon S, Zhang JG, Vremec D, Brady JL, Bouillet P, Wu L, Huang DC, Wicks IP, Morand EF, Strasser A, Lew AM.

Arthritis Rheumatol. 2015 Mar;67(3):797-808. doi: 10.1002/art.38966.

18.

S1PR4 Signaling Attenuates ILT 7 Internalization To Limit IFN-α Production by Human Plasmacytoid Dendritic Cells.

Dillmann C, Ringel C, Ringleb J, Mora J, Olesch C, Fink AF, Roberts E, Brüne B, Weigert A.

J Immunol. 2016 Feb 15;196(4):1579-90. doi: 10.4049/jimmunol.1403168.

20.

Evaluating the role of nucleic acid antigens in murine models of systemic lupus erythematosus.

Watkins AA, Bonegio RG, Rifkin IR.

Methods Mol Biol. 2014;1169:143-58. doi: 10.1007/978-1-4939-0882-0_14.

PMID:
24957237
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