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Items: 1 to 20 of 109

1.

IL-17RC is required for immune signaling via an extended SEF/IL-17R signaling domain in the cytoplasmic tail.

Ho AW, Shen F, Conti HR, Patel N, Childs EE, Peterson AC, Hernández-Santos N, Kolls JK, Kane LP, Ouyang W, Gaffen SL.

J Immunol. 2010 Jul 15;185(2):1063-70. doi: 10.4049/jimmunol.0903739. Epub 2010 Jun 16.

2.

SEF/IL-17R (SEFIR) is not enough: an extended SEFIR domain is required for il-17RA-mediated signal transduction.

Onishi RM, Park SJ, Hanel W, Ho AW, Maitra A, Gaffen SL.

J Biol Chem. 2010 Oct 22;285(43):32751-9. doi: 10.1074/jbc.M110.121418. Epub 2010 Aug 20.

3.

A CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17- and IL-25-induced inflammation.

Liu C, Swaidani S, Qian W, Kang Z, Sun P, Han Y, Wang C, Gulen MF, Yin W, Zhang C, Fox PL, Aronica M, Hamilton TA, Misra S, Deng J, Li X.

Sci Signal. 2011 Nov 1;4(197):ra72. doi: 10.1126/scisignal.2001843.

4.

Crystal structure of IL-17 receptor B SEFIR domain.

Zhang B, Liu C, Qian W, Han Y, Li X, Deng J.

J Immunol. 2013 Mar 1;190(5):2320-6. doi: 10.4049/jimmunol.1202922. Epub 2013 Jan 25. Erratum in: J Immunol. 2013 May 1;190(9):4910.

5.

IL-17RC is required for IL-17A- and IL-17F-dependent signaling and the pathogenesis of experimental autoimmune encephalomyelitis.

Hu Y, Ota N, Peng I, Refino CJ, Danilenko DM, Caplazi P, Ouyang W.

J Immunol. 2010 Apr 15;184(8):4307-16. doi: 10.4049/jimmunol.0903614. Epub 2010 Mar 15.

6.

IL-17RC: a partner in IL-17 signaling and beyond.

Ho AW, Gaffen SL.

Semin Immunopathol. 2010 Mar;32(1):33-42. doi: 10.1007/s00281-009-0185-0. Epub 2009 Dec 13. Review.

7.

Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved α-helix for Act1 binding and IL-17 signaling.

Zhang B, Liu C, Qian W, Han Y, Li X, Deng J.

Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1476-83. doi: 10.1107/S1399004714005227. Epub 2014 Apr 30.

8.

The anaphase-promoting complex protein 5 (AnapC5) associates with A20 and inhibits IL-17-mediated signal transduction.

Ho AW, Garg AV, Monin L, Simpson-Abelson MR, Kinner L, Gaffen SL.

PLoS One. 2013 Jul 29;8(7):e70168. doi: 10.1371/journal.pone.0070168. Print 2013.

9.

Antibody blockade of IL-17 family cytokines in immunity to acute murine oral mucosal candidiasis.

Whibley N, Tritto E, Traggiai E, Kolbinger F, Moulin P, Brees D, Coleman BM, Mamo AJ, Garg AV, Jaycox JR, Siebenlist U, Kammüller M, Gaffen SL.

J Leukoc Biol. 2016 Jun;99(6):1153-64. doi: 10.1189/jlb.4A0915-428R. Epub 2016 Jan 4. Erratum in: J Leukoc Biol. 2017 Apr;101(4):1065.

10.
11.

Signaling through IL-17C/IL-17RE is dispensable for immunity to systemic, oral and cutaneous candidiasis.

Conti HR, Whibley N, Coleman BM, Garg AV, Jaycox JR, Gaffen SL.

PLoS One. 2015 Apr 7;10(4):e0122807. doi: 10.1371/journal.pone.0122807. eCollection 2015.

12.

The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease.

Qian Y, Liu C, Hartupee J, Altuntas CZ, Gulen MF, Jane-Wit D, Xiao J, Lu Y, Giltiay N, Liu J, Kordula T, Zhang QW, Vallance B, Swaidani S, Aronica M, Tuohy VK, Hamilton T, Li X.

Nat Immunol. 2007 Mar;8(3):247-56. Epub 2007 Feb 4.

PMID:
17277779
13.

The IL-17F/IL-17RC Axis Promotes Respiratory Allergy in the Proximal Airways.

De Luca A, Pariano M, Cellini B, Costantini C, Villella VR, Jose SS, Palmieri M, Borghi M, Galosi C, Paolicelli G, Maiuri L, Fric J, Zelante T.

Cell Rep. 2017 Aug 15;20(7):1667-1680. doi: 10.1016/j.celrep.2017.07.063.

14.

The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex.

Wright JF, Bennett F, Li B, Brooks J, Luxenberg DP, Whitters MJ, Tomkinson KN, Fitz LJ, Wolfman NM, Collins M, Dunussi-Joannopoulos K, Chatterjee-Kishore M, Carreno BM.

J Immunol. 2008 Aug 15;181(4):2799-805.

15.

Persistent stimulation with interleukin-17 desensitizes cells through SCFβ-TrCP-mediated degradation of Act1.

Shi P, Zhu S, Lin Y, Liu Y, Liu Y, Chen Z, Shi Y, Qian Y.

Sci Signal. 2011 Nov 1;4(197):ra73. doi: 10.1126/scisignal.2001653.

16.

Interleukin-17-induced protein lipocalin 2 is dispensable for immunity to oral candidiasis.

Ferreira MC, Whibley N, Mamo AJ, Siebenlist U, Chan YR, Gaffen SL.

Infect Immun. 2014 Mar;82(3):1030-5. doi: 10.1128/IAI.01389-13. Epub 2013 Dec 16.

17.

Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F.

Kuestner RE, Taft DW, Haran A, Brandt CS, Brender T, Lum K, Harder B, Okada S, Ostrander CD, Kreindler JL, Aujla SJ, Reardon B, Moore M, Shea P, Schreckhise R, Bukowski TR, Presnell S, Guerra-Lewis P, Parrish-Novak J, Ellsworth JL, Jaspers S, Lewis KE, Appleby M, Kolls JK, Rixon M, West JW, Gao Z, Levin SD.

J Immunol. 2007 Oct 15;179(8):5462-73.

18.

Molecular characterization and evolution analysis of five interleukin-17 receptor genes in large yellow croaker Larimichthys crocea.

Ding Y, Ai C, Mu Y, Ao J, Chen X.

Fish Shellfish Immunol. 2016 Nov;58:332-339. doi: 10.1016/j.fsi.2016.09.017. Epub 2016 Sep 12.

PMID:
27633682
19.

Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.

Liu C, Qian W, Qian Y, Giltiay NV, Lu Y, Swaidani S, Misra S, Deng L, Chen ZJ, Li X.

Sci Signal. 2009 Oct 13;2(92):ra63. doi: 10.1126/scisignal.2000382. Erratum in: Sci Signal. 2010;3(121):er3.

20.

Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression.

Maitra A, Shen F, Hanel W, Mossman K, Tocker J, Swart D, Gaffen SL.

Proc Natl Acad Sci U S A. 2007 May 1;104(18):7506-11. Epub 2007 Apr 24.

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