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Items: 1 to 20 of 83


Visual cycle: Dependence of retinol production and removal on photoproduct decay and cell morphology.

Ala-Laurila P, Kolesnikov AV, Crouch RK, Tsina E, Shukolyukov SA, Govardovskii VI, Koutalos Y, Wiggert B, Estevez ME, Cornwall MC.

J Gen Physiol. 2006 Aug;128(2):153-69. Epub 2006 Jul 17.


Formation of all-trans retinol after visual pigment bleaching in mouse photoreceptors.

Chen C, Blakeley LR, Koutalos Y.

Invest Ophthalmol Vis Sci. 2009 Aug;50(8):3589-95. doi: 10.1167/iovs.08-3336. Epub 2009 Mar 5.


cis Retinol oxidation regulates photoreceptor access to the retina visual cycle and cone pigment regeneration.

Sato S, Kefalov VJ.

J Physiol. 2016 Nov 15;594(22):6753-6765. doi: 10.1113/JP272831. Epub 2016 Aug 2.


Preparation of living isolated vertebrate photoreceptor cells for fluorescence imaging.

Boyer NP, Chen C, Koutalos Y.

J Vis Exp. 2011 Jun 22;(52). pii: 2789. doi: 10.3791/2789.


Physiological and microfluorometric studies of reduction and clearance of retinal in bleached rod photoreceptors.

Tsina E, Chen C, Koutalos Y, Ala-Laurila P, Tsacopoulos M, Wiggert B, Crouch RK, Cornwall MC.

J Gen Physiol. 2004 Oct;124(4):429-43.


Kinetics of rhodopsin's chromophore monitored in a single photoreceptor.

Adler L 4th, Boyer NP, Chen C, Koutalos Y.

Methods Mol Biol. 2015;1271:327-43. doi: 10.1007/978-1-4939-2330-4_21.


The retina visual cycle is driven by cis retinol oxidation in the outer segments of cones.

Sato S, Frederiksen R, Cornwall MC, Kefalov VJ.

Vis Neurosci. 2017 Jan;34:E004. doi: 10.1017/S0952523817000013.


Reduction of all-trans retinal to all-trans retinol in the outer segments of frog and mouse rod photoreceptors.

Chen C, Tsina E, Cornwall MC, Crouch RK, Vijayaraghavan S, Koutalos Y.

Biophys J. 2005 Mar;88(3):2278-87. Epub 2004 Dec 30.


Analysis of the retinoid isomerase activities in the retinal pigment epithelium and retina.

Travis GH, Kaylor J, Yuan Q.

Methods Mol Biol. 2010;652:329-39. doi: 10.1007/978-1-60327-325-1_19.


All-trans retinol in rod photoreceptor outer segments moves unrestrictedly by passive diffusion.

Wu Q, Chen C, Koutalos Y.

Biophys J. 2006 Dec 15;91(12):4678-89. Epub 2006 Sep 29.


Interphotoreceptor retinoid-binding protein is the physiologically relevant carrier that removes retinol from rod photoreceptor outer segments.

Wu Q, Blakeley LR, Cornwall MC, Crouch RK, Wiggert BN, Koutalos Y.

Biochemistry. 2007 Jul 24;46(29):8669-79. Epub 2007 Jun 30.


All-trans retinal mediates light-induced oxidation in single living rod photoreceptors.

Masutomi K, Chen C, Nakatani K, Koutalos Y.

Photochem Photobiol. 2012 Nov-Dec;88(6):1356-61. doi: 10.1111/j.1751-1097.2012.01129.x. Epub 2012 Mar 28.


Reduction of all-trans-retinal in vertebrate rod photoreceptors requires the combined action of RDH8 and RDH12.

Chen C, Thompson DA, Koutalos Y.

J Biol Chem. 2012 Jul 13;287(29):24662-70. doi: 10.1074/jbc.M112.354514. Epub 2012 May 23.


ATP-binding cassette transporter ABCA4 and chemical isomerization protect photoreceptor cells from the toxic accumulation of excess 11-cis-retinal.

Quazi F, Molday RS.

Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):5024-9. doi: 10.1073/pnas.1400780111. Epub 2014 Mar 20.


Metabolic constraints on the recovery of sensitivity after visual pigment bleaching in retinal rods.

Miyagishima KJ, Cornwall MC, Sampath AP.

J Gen Physiol. 2009 Sep;134(3):165-75. doi: 10.1085/jgp.200910267. Epub 2009 Aug 17.


Rapid formation of all-trans retinol after bleaching in frog and mouse rod photoreceptor outer segments.

Chen C, Koutalos Y.

Photochem Photobiol Sci. 2010 Nov;9(11):1475-9. doi: 10.1039/c0pp00124d. Epub 2010 Aug 9.


Visual cycle and its metabolic support in gecko photoreceptors.

Kolesnikov AV, Ala-Laurila P, Shukolyukov SA, Crouch RK, Wiggert B, Estevez ME, Govardovskii VI, Cornwall MC.

Vision Res. 2007 Feb;47(3):363-74. Epub 2006 Oct 16.


Low aqueous solubility of 11-cis-retinal limits the rate of pigment formation and dark adaptation in salamander rods.

Frederiksen R, Boyer NP, Nickle B, Chakrabarti KS, Koutalos Y, Crouch RK, Oprian D, Cornwall MC.

J Gen Physiol. 2012 Jun;139(6):493-505. doi: 10.1085/jgp.201110685. Erratum in: J Gen Physiol. 2014 Nov;144(5):487.

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