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Items: 1 to 20 of 249

1.

Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice.

Ceppa E, Cattaruzza F, Lyo V, Amadesi S, Pelayo JC, Poole DP, Vaksman N, Liedtke W, Cohen DM, Grady EF, Bunnett NW, Kirkwood KS.

Am J Physiol Gastrointest Liver Physiol. 2010 Sep;299(3):G556-71. doi: 10.1152/ajpgi.00433.2009. Epub 2010 Jun 10.

2.

Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice.

Cattaruzza F, Spreadbury I, Miranda-Morales M, Grady EF, Vanner S, Bunnett NW.

Am J Physiol Gastrointest Liver Physiol. 2010 Jan;298(1):G81-91. doi: 10.1152/ajpgi.00221.2009. Epub 2009 Oct 29.

3.

TRPV1 and TRPA1 antagonists prevent the transition of acute to chronic inflammation and pain in chronic pancreatitis.

Schwartz ES, La JH, Scheff NN, Davis BM, Albers KM, Gebhart GF.

J Neurosci. 2013 Mar 27;33(13):5603-11. doi: 10.1523/JNEUROSCI.1806-12.2013.

4.

Synergistic role of TRPV1 and TRPA1 in pancreatic pain and inflammation.

Schwartz ES, Christianson JA, Chen X, La JH, Davis BM, Albers KM, Gebhart GF.

Gastroenterology. 2011 Apr;140(4):1283-1291.e1-2. doi: 10.1053/j.gastro.2010.12.033. Epub 2010 Dec 24.

5.

Roles of Cav3.2 and TRPA1 channels targeted by hydrogen sulfide in pancreatic nociceptive processing in mice with or without acute pancreatitis.

Terada Y, Fujimura M, Nishimura S, Tsubota M, Sekiguchi F, Kawabata A.

J Neurosci Res. 2015 Feb;93(2):361-9. doi: 10.1002/jnr.23490. Epub 2014 Sep 30.

PMID:
25267397
6.

Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1.

Materazzi S, Nassini R, Andrè E, Campi B, Amadesi S, Trevisani M, Bunnett NW, Patacchini R, Geppetti P.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):12045-50. doi: 10.1073/pnas.0802354105. Epub 2008 Aug 7.

7.

Possible involvement of TRPV1 and TRPV4 in nociceptive stimulation- induced nocifensive behavior and neuroendocrine response in mice.

Ishikura T, Suzuki H, Shoguchi K, Koreeda Y, Aritomi T, Matsuura T, Yoshimura M, Ohkubo J, Maruyama T, Kawasaki M, Ohnishi H, Sakai A, Mizuno A, Suzuki M, Ueta Y.

Brain Res Bull. 2015 Sep;118:7-16. doi: 10.1016/j.brainresbull.2015.08.004. Epub 2015 Aug 24.

PMID:
26314785
8.

Cannabinoids desensitize capsaicin and mustard oil responses in sensory neurons via TRPA1 activation.

Akopian AN, Ruparel NB, Patwardhan A, Hargreaves KM.

J Neurosci. 2008 Jan 30;28(5):1064-75. doi: 10.1523/JNEUROSCI.1565-06.2008.

9.

Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome.

Cenac N, Bautzova T, Le Faouder P, Veldhuis NA, Poole DP, Rolland C, Bertrand J, Liedtke W, Dubourdeau M, Bertrand-Michel J, Zecchi L, Stanghellini V, Bunnett NW, Barbara G, Vergnolle N.

Gastroenterology. 2015 Aug;149(2):433-44.e7. doi: 10.1053/j.gastro.2015.04.011. Epub 2015 Apr 22.

PMID:
25911511
10.

Transient receptor potential V1 regulates activation and modulation of transient receptor potential A1 by Ca2+.

Patil MJ, Jeske NA, Akopian AN.

Neuroscience. 2010 Dec 29;171(4):1109-19. doi: 10.1016/j.neuroscience.2010.09.031. Epub 2010 Sep 25.

11.

Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis.

Wick EC, Hoge SG, Grahn SW, Kim E, Divino LA, Grady EF, Bunnett NW, Kirkwood KS.

Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G959-69. Epub 2006 Jan 6.

12.

The general anesthetic propofol excites nociceptors by activating TRPV1 and TRPA1 rather than GABAA receptors.

Fischer MJ, Leffler A, Niedermirtl F, Kistner K, Eberhardt M, Reeh PW, Nau C.

J Biol Chem. 2010 Nov 5;285(45):34781-92. doi: 10.1074/jbc.M110.143958. Epub 2010 Sep 7.

13.

TRPV1, TRPA1, and CB1 in the isolated vagus nerve--axonal chemosensitivity and control of neuropeptide release.

Weller K, Reeh PW, Sauer SK.

Neuropeptides. 2011 Dec;45(6):391-400. doi: 10.1016/j.npep.2011.07.011. Epub 2011 Aug 24.

PMID:
21868092
14.

TRPA1 and TRPV4 activation in human odontoblasts stimulates ATP release.

Egbuniwe O, Grover S, Duggal AK, Mavroudis A, Yazdi M, Renton T, Di Silvio L, Grant AD.

J Dent Res. 2014 Sep;93(9):911-7. doi: 10.1177/0022034514544507. Epub 2014 Jul 25.

15.

The capsaicin receptor TRPV1 is a crucial mediator of the noxious effects of mustard oil.

Everaerts W, Gees M, Alpizar YA, Farre R, Leten C, Apetrei A, Dewachter I, van Leuven F, Vennekens R, De Ridder D, Nilius B, Voets T, Talavera K.

Curr Biol. 2011 Feb 22;21(4):316-21. doi: 10.1016/j.cub.2011.01.031.

16.

High concentrations of morphine sensitize and activate mouse dorsal root ganglia via TRPV1 and TRPA1 receptors.

Forster AB, Reeh PW, Messlinger K, Fischer MJ.

Mol Pain. 2009 Apr 16;5:17. doi: 10.1186/1744-8069-5-17.

17.

Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice.

Grant AD, Cottrell GS, Amadesi S, Trevisani M, Nicoletti P, Materazzi S, Altier C, Cenac N, Zamponi GW, Bautista-Cruz F, Lopez CB, Joseph EK, Levine JD, Liedtke W, Vanner S, Vergnolle N, Geppetti P, Bunnett NW.

J Physiol. 2007 Feb 1;578(Pt 3):715-33. Epub 2006 Nov 23.

18.

Activation of TRPA1 channels by the fatty acid amide hydrolase inhibitor 3'-carbamoylbiphenyl-3-yl cyclohexylcarbamate (URB597).

Niforatos W, Zhang XF, Lake MR, Walter KA, Neelands T, Holzman TF, Scott VE, Faltynek CR, Moreland RB, Chen J.

Mol Pharmacol. 2007 May;71(5):1209-16. Epub 2007 Feb 21.

19.

Nociceptive and pro-inflammatory effects of dimethylallyl pyrophosphate via TRPV4 activation.

Bang S, Yoo S, Yang TJ, Cho H, Hwang SW.

Br J Pharmacol. 2012 Jun;166(4):1433-43. doi: 10.1111/j.1476-5381.2012.01884.x.

20.

Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels.

Riera CE, Menozzi-Smarrito C, Affolter M, Michlig S, Munari C, Robert F, Vogel H, Simon SA, le Coutre J.

Br J Pharmacol. 2009 Aug;157(8):1398-409. doi: 10.1111/j.1476-5381.2009.00307.x. Epub 2009 Jul 8.

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