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Items: 1 to 20 of 137

1.

CARD9 mediates dectin-2-induced IkappaBalpha kinase ubiquitination leading to activation of NF-kappaB in response to stimulation by the hyphal form of Candida albicans.

Bi L, Gojestani S, Wu W, Hsu YM, Zhu J, Ariizumi K, Lin X.

J Biol Chem. 2010 Aug 20;285(34):25969-77. doi: 10.1074/jbc.M110.131300.

2.

Activation of NF-κB and respiratory burst following Aspergillus fumigatus stimulation of macrophages.

Sun H, Xu XY, Tian XL, Shao HT, Wu XD, Wang Q, Su X, Shi Y.

Immunobiology. 2014 Jan;219(1):25-36. doi: 10.1016/j.imbio.2013.06.013.

PMID:
23886693
3.

CARD9 mediates Dectin-1-induced ERK activation by linking Ras-GRF1 to H-Ras for antifungal immunity.

Jia XM, Tang B, Zhu LL, Liu YH, Zhao XQ, Gorjestani S, Hsu YM, Yang L, Guan JH, Xu GT, Lin X.

J Exp Med. 2014 Oct 20;211(11):2307-21. doi: 10.1084/jem.20132349.

4.

Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity.

Strasser D, Neumann K, Bergmann H, Marakalala MJ, Guler R, Rojowska A, Hopfner KP, Brombacher F, Urlaub H, Baier G, Brown GD, Leitges M, Ruland J.

Immunity. 2012 Jan 27;36(1):32-42. doi: 10.1016/j.immuni.2011.11.015.

5.

C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation.

Zhao XQ, Zhu LL, Chang Q, Jiang C, You Y, Luo T, Jia XM, Lin X.

J Biol Chem. 2014 Oct 24;289(43):30052-62. doi: 10.1074/jbc.M114.588574.

6.

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity.

Gross O, Gewies A, Finger K, Schäfer M, Sparwasser T, Peschel C, Förster I, Ruland J.

Nature. 2006 Aug 10;442(7103):651-6.

PMID:
16862125
7.

CARD9 Syk-dependent and Raf-1 Syk-independent signaling pathways in target recognition of Candida albicans by Dectin-1.

Yang H, He H, Dong Y.

Eur J Clin Microbiol Infect Dis. 2011 Mar;30(3):303-5. doi: 10.1007/s10096-010-1103-z. Review.

PMID:
21108038
8.

Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells.

Xu S, Huo J, Lee KG, Kurosaki T, Lam KP.

J Biol Chem. 2009 Mar 13;284(11):7038-46. doi: 10.1074/jbc.M806650200.

9.

Barley-derived beta-D-glucan induces immunostimulation via a dectin-1-mediated pathway.

Tada R, Ikeda F, Aoki K, Yoshikawa M, Kato Y, Adachi Y, Tanioka A, Ishibashi K, Tsubaki K, Ohno N.

Immunol Lett. 2009 Apr 27;123(2):144-8. doi: 10.1016/j.imlet.2009.03.005.

PMID:
19428562
10.

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17.

LeibundGut-Landmann S, Gross O, Robinson MJ, Osorio F, Slack EC, Tsoni SV, Schweighoffer E, Tybulewicz V, Brown GD, Ruland J, Reis e Sousa C.

Nat Immunol. 2007 Jun;8(6):630-8.

PMID:
17450144
11.

Recognition of Candida albicans by Dectin-1 induces mast cell activation.

Nieto-Patlán A, Campillo-Navarro M, Rodríguez-Cortés O, Muñoz-Cruz S, Wong-Baeza I, Estrada-Parra S, Estrada-García I, Serafín-López J, Chacón-Salinas R.

Immunobiology. 2015 Sep;220(9):1093-100. doi: 10.1016/j.imbio.2015.05.005.

PMID:
26001731
12.

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection.

Robinson MJ, Osorio F, Rosas M, Freitas RP, Schweighoffer E, Gross O, Verbeek JS, Ruland J, Tybulewicz V, Brown GD, Moita LF, Taylor PR, Reis e Sousa C.

J Exp Med. 2009 Aug 31;206(9):2037-51. doi: 10.1084/jem.20082818.

13.

Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-kappaB activation through Raf-1 and Syk.

Gringhuis SI, den Dunnen J, Litjens M, van der Vlist M, Wevers B, Bruijns SC, Geijtenbeek TB.

Nat Immunol. 2009 Feb;10(2):203-13. doi: 10.1038/ni.1692.

PMID:
19122653
14.

Cell type-specific regulation of ITAM-mediated NF-kappaB activation by the adaptors, CARMA1 and CARD9.

Hara H, Ishihara C, Takeuchi A, Xue L, Morris SW, Penninger JM, Yoshida H, Saito T.

J Immunol. 2008 Jul 15;181(2):918-30.

15.

Differential use of CARD9 by dectin-1 in macrophages and dendritic cells.

Goodridge HS, Shimada T, Wolf AJ, Hsu YM, Becker CA, Lin X, Underhill DM.

J Immunol. 2009 Jan 15;182(2):1146-54.

16.

C-type lectin receptors Dectin-3 and Dectin-2 form a heterodimeric pattern-recognition receptor for host defense against fungal infection.

Zhu LL, Zhao XQ, Jiang C, You Y, Chen XP, Jiang YY, Jia XM, Lin X.

Immunity. 2013 Aug 22;39(2):324-34. doi: 10.1016/j.immuni.2013.05.017.

17.

SHIP-1 Couples to the Dectin-1 hemITAM and Selectively Modulates Reactive Oxygen Species Production in Dendritic Cells in Response to Candida albicans.

Blanco-Menéndez N, del Fresno C, Fernandes S, Calvo E, Conde-Garrosa R, Kerr WG, Sancho D.

J Immunol. 2015 Nov 1;195(9):4466-78. doi: 10.4049/jimmunol.1402874.

18.

C-type lectin receptor-induced NF-κB activation in innate immune and inflammatory responses.

Kingeter LM, Lin X.

Cell Mol Immunol. 2012 Mar;9(2):105-12. doi: 10.1038/cmi.2011.58. Review.

19.

Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans.

Saijo S, Ikeda S, Yamabe K, Kakuta S, Ishigame H, Akitsu A, Fujikado N, Kusaka T, Kubo S, Chung SH, Komatsu R, Miura N, Adachi Y, Ohno N, Shibuya K, Yamamoto N, Kawakami K, Yamasaki S, Saito T, Akira S, Iwakura Y.

Immunity. 2010 May 28;32(5):681-91. doi: 10.1016/j.immuni.2010.05.001.

20.

Mincle Activation and the Syk/Card9 Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye.

Lee EJ, Brown BR, Vance EE, Snow PE, Silver PB, Heinrichs D, Lin X, Iwakura Y, Wells CA, Caspi RR, Rosenzweig HL.

J Immunol. 2016 Apr 1;196(7):3148-58. doi: 10.4049/jimmunol.1502355.

PMID:
26921309

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