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Items: 1 to 20 of 98

1.

Cytotoxic immunological synapses.

Dustin ML, Long EO.

Immunol Rev. 2010 May;235(1):24-34. doi: 10.1111/j.0105-2896.2010.00904.x. Review.

2.

Natural killer cell cytotoxicity: how do they pull the trigger?

Topham NJ, Hewitt EW.

Immunology. 2009 Sep;128(1):7-15. doi: 10.1111/j.1365-2567.2009.03123.x. Review.

3.

Perforin: structure, function, and role in human immunopathology.

Voskoboinik I, Dunstone MA, Baran K, Whisstock JC, Trapani JA.

Immunol Rev. 2010 May;235(1):35-54. doi: 10.1111/j.0105-2896.2010.00896.x. Review.

PMID:
20536554
4.

Molecular mechanisms of biogenesis and exocytosis of cytotoxic granules.

de Saint Basile G, Ménasché G, Fischer A.

Nat Rev Immunol. 2010 Aug;10(8):568-79. doi: 10.1038/nri2803. Epub 2010 Jul 16. Review.

PMID:
20634814
5.

The synapse and cytolytic machinery of cytotoxic T cells.

Jenkins MR, Griffiths GM.

Curr Opin Immunol. 2010 Jun;22(3):308-13. doi: 10.1016/j.coi.2010.02.008. Epub 2010 Mar 11. Review.

6.

Navigating barriers: the challenge of directed secretion at the natural killer cell lytic immunological synapse.

Sanborn KB, Orange JS.

J Clin Immunol. 2010 May;30(3):358-63. doi: 10.1007/s10875-010-9372-y. Epub 2010 Feb 27. Review.

7.

Reduced release and binding of perforin at the immunological synapse underlies the age-related decline in natural killer cell cytotoxicity.

Hazeldine J, Hampson P, Lord JM.

Aging Cell. 2012 Oct;11(5):751-9. doi: 10.1111/j.1474-9726.2012.00839.x. Epub 2012 Jun 19.

8.

Role of centrosome in regulating immune response.

Kumar A, Rajendran V, Sethumadhavan R, Purohit R.

Curr Drug Targets. 2014 May;15(5):558-63. Review.

PMID:
24655141
9.

The battlefield of perforin/granzyme cell death pathways.

Hoves S, Trapani JA, Voskoboinik I.

J Leukoc Biol. 2010 Feb;87(2):237-43. doi: 10.1189/jlb.0909608. Epub 2009 Nov 13. Review.

PMID:
19915166
10.

Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses.

Liu D, Bryceson YT, Meckel T, Vasiliver-Shamis G, Dustin ML, Long EO.

Immunity. 2009 Jul 17;31(1):99-109. doi: 10.1016/j.immuni.2009.05.009.

11.

Centriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systems.

Stinchcombe JC, Salio M, Cerundolo V, Pende D, Arico M, Griffiths GM.

BMC Biol. 2011 Jun 28;9:45. doi: 10.1186/1741-7007-9-45.

12.

Origins of the cytolytic synapse.

de la Roche M, Asano Y, Griffiths GM.

Nat Rev Immunol. 2016 Jul;16(7):421-32. doi: 10.1038/nri.2016.54. Epub 2016 Jun 6. Review.

PMID:
27265595
13.

Cell polarisation and the immunological synapse.

Angus KL, Griffiths GM.

Curr Opin Cell Biol. 2013 Feb;25(1):85-91. doi: 10.1016/j.ceb.2012.08.013. Epub 2012 Sep 16. Review.

14.

Cytokine secretion is distinct from secretion of cytotoxic granules in NK cells.

Reefman E, Kay JG, Wood SM, Offenhäuser C, Brown DL, Roy S, Stanley AC, Low PC, Manderson AP, Stow JL.

J Immunol. 2010 May 1;184(9):4852-62. doi: 10.4049/jimmunol.0803954. Epub 2010 Apr 5.

15.

Formation and function of the lytic NK-cell immunological synapse.

Orange JS.

Nat Rev Immunol. 2008 Sep;8(9):713-25. doi: 10.1038/nri2381. Review.

16.

The secretory synapse: the secrets of a serial killer.

Bossi G, Trambas C, Booth S, Clark R, Stinchcombe J, Griffiths GM.

Immunol Rev. 2002 Nov;189:152-60. Review.

PMID:
12445272
17.

Gap junction intercellular communications regulate NK cell activation and modulate NK cytotoxic capacity.

Tittarelli A, Mendoza-Naranjo A, Farías M, Guerrero I, Ihara F, Wennerberg E, Riquelme S, Gleisner A, Kalergis A, Lundqvist A, López MN, Chambers BJ, Salazar-Onfray F.

J Immunol. 2014 Feb 1;192(3):1313-9. doi: 10.4049/jimmunol.1301297. Epub 2013 Dec 27.

18.

Cytotoxic T lymphocytes and natural killer cells display impaired cytotoxic functions and reduced activation in patients with alcoholic hepatitis.

Støy S, Dige A, Sandahl TD, Laursen TL, Buus C, Hokland M, Vilstrup H.

Am J Physiol Gastrointest Liver Physiol. 2015 Feb 15;308(4):G269-76. doi: 10.1152/ajpgi.00200.2014. Epub 2014 Dec 11.

19.

Cell biological steps and checkpoints in accessing NK cell cytotoxicity.

Mace EM, Dongre P, Hsu HT, Sinha P, James AM, Mann SS, Forbes LR, Watkin LB, Orange JS.

Immunol Cell Biol. 2014 Mar;92(3):245-55. doi: 10.1038/icb.2013.96. Epub 2014 Jan 21. Review.

20.

Death ligands and granulysin: mechanisms of tumor cell death induction and therapeutic opportunities.

Martinez-Lostao L, de Miguel D, Al-Wasaby S, Gallego-Lleyda A, Anel A.

Immunotherapy. 2015;7(8):883-2. doi: 10.2217/imt.15.56. Epub 2015 Aug 28. Review.

PMID:
26314314

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