Similar articles for PMID: 20527968

Year	Number of Results
2002	1
2003	6
2004	17
2005	26
2006	30
2007	21
2008	17
2009	10
2010	6
2011	9
2012	3
2013	9
2014	16
2015	8
2016	5
2017	4
2018	4
2019	1
2020	13
2021	9
2022	7
2023	1
2024	0

1

Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein-ligand X-ray structure and biological evaluation.

Ghosh AK, Takayama J, Rao KV, Ratia K, Chaudhuri R, Mulhearn DC, Lee H, Nichols DB, Baliji S, Baker SC, Johnson ME, Mesecar AD. Ghosh AK, et al. J Med Chem. 2010 Jul 8;53(13):4968-79. doi: 10.1021/jm1004489. J Med Chem. 2010. PMID: 20527968 Free PMC article.

2

Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease.

Ghosh AK, Takayama J, Aubin Y, Ratia K, Chaudhuri R, Baez Y, Sleeman K, Coughlin M, Nichols DB, Mulhearn DC, Prabhakar BS, Baker SC, Johnson ME, Mesecar AD. Ghosh AK, et al. J Med Chem. 2009 Aug 27;52(16):5228-40. doi: 10.1021/jm900611t. J Med Chem. 2009. PMID: 19645480 Free PMC article.

3

A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication.

Ratia K, Pegan S, Takayama J, Sleeman K, Coughlin M, Baliji S, Chaudhuri R, Fu W, Prabhakar BS, Johnson ME, Baker SC, Ghosh AK, Mesecar AD. Ratia K, et al. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16119-24. doi: 10.1073/pnas.0805240105. Epub 2008 Oct 13. Proc Natl Acad Sci U S A. 2008. PMID: 18852458 Free PMC article.

4

The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds.

Báez-Santos YM, St John SE, Mesecar AD. Báez-Santos YM, et al. Antiviral Res. 2015 Mar;115:21-38. doi: 10.1016/j.antiviral.2014.12.015. Epub 2014 Dec 29. Antiviral Res. 2015. PMID: 25554382 Free PMC article. Review.

5

Substrate specificity profiling and identification of a new class of inhibitor for the major protease of the SARS coronavirus.

Goetz DH, Choe Y, Hansell E, Chen YT, McDowell M, Jonsson CB, Roush WR, McKerrow J, Craik CS. Goetz DH, et al. Biochemistry. 2007 Jul 31;46(30):8744-52. doi: 10.1021/bi0621415. Epub 2007 Jul 3. Biochemistry. 2007. PMID: 17605471

6

Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV.

Lee H, Lei H, Santarsiero BD, Gatuz JL, Cao S, Rice AJ, Patel K, Szypulinski MZ, Ojeda I, Ghosh AK, Johnson ME. Lee H, et al. ACS Chem Biol. 2015 Jun 19;10(6):1456-65. doi: 10.1021/cb500917m. Epub 2015 Mar 16. ACS Chem Biol. 2015. PMID: 25746232 Free PMC article.

7

Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro.

Chen L, Gui C, Luo X, Yang Q, Günther S, Scandella E, Drosten C, Bai D, He X, Ludewig B, Chen J, Luo H, Yang Y, Yang Y, Zou J, Thiel V, Chen K, Shen J, Shen X, Jiang H. Chen L, et al. J Virol. 2005 Jun;79(11):7095-103. doi: 10.1128/JVI.79.11.7095-7103.2005. J Virol. 2005. PMID: 15890949 Free PMC article.

8

Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor.

Yang S, Chen SJ, Hsu MF, Wu JD, Tseng CT, Liu YF, Chen HC, Kuo CW, Wu CS, Chang LW, Chen WC, Liao SY, Chang TY, Hung HH, Shr HL, Liu CY, Huang YA, Chang LY, Hsu JC, Peters CJ, Wang AH, Hsu MC. Yang S, et al. J Med Chem. 2006 Aug 10;49(16):4971-80. doi: 10.1021/jm0603926. J Med Chem. 2006. PMID: 16884309

9

Synthesis and activity of an octapeptide inhibitor designed for SARS coronavirus main proteinase.

Gan YR, Huang H, Huang YD, Rao CM, Zhao Y, Liu JS, Wu L, Wei DQ. Gan YR, et al. Peptides. 2006 Apr;27(4):622-5. doi: 10.1016/j.peptides.2005.09.006. Epub 2005 Oct 19. Peptides. 2006. PMID: 16242214 Free PMC article.

10

Development of a red-shifted fluorescence-based assay for SARS-coronavirus 3CL protease: identification of a novel class of anti-SARS agents from the tropical marine sponge Axinella corrugata.

Hamill P, Hudson D, Kao RY, Chow P, Raj M, Xu H, Richer MJ, Jean F. Hamill P, et al. Biol Chem. 2006 Aug;387(8):1063-74. doi: 10.1515/BC.2006.131. Biol Chem. 2006. PMID: 16895476

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