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Items: 1 to 20 of 125

1.

Molecular targeting of carbonic anhydrase IX in mice with hypoxic HT29 colorectal tumor xenografts.

Carlin S, Khan N, Ku T, Longo VA, Larson SM, Smith-Jones PM.

PLoS One. 2010 May 27;5(5):e10857. doi: 10.1371/journal.pone.0010857.

2.

PET of hypoxia with 89Zr-labeled cG250-F(ab')2 in head and neck tumors.

Hoeben BA, Kaanders JH, Franssen GM, Troost EG, Rijken PF, Oosterwijk E, van Dongen GA, Oyen WJ, Boerman OC, Bussink J.

J Nucl Med. 2010 Jul;51(7):1076-83. doi: 10.2967/jnumed.109.073189. Epub 2010 Jun 16.

3.

Investigation of hypoxia and carbonic anhydrase IX expression in a renal cell carcinoma xenograft model with oxygen tension measurements and ¹²⁴I-cG250 PET/CT.

Lawrentschuk N, Lee FT, Jones G, Rigopoulos A, Mountain A, O'Keefe G, Papenfuss AT, Bolton DM, Davis ID, Scott AM.

Urol Oncol. 2011 Jul-Aug;29(4):411-20. doi: 10.1016/j.urolonc.2009.03.028. Epub 2009 Jun 12.

PMID:
19523858
4.

Evaluation of CAIX and CAXII Expression in Breast Cancer at Varied O2 Levels: CAIX is the Superior Surrogate Imaging Biomarker of Tumor Hypoxia.

Tafreshi NK, Lloyd MC, Proemsey JB, Bui MM, Kim J, Gillies RJ, Morse DL.

Mol Imaging Biol. 2016 Apr;18(2):219-31. doi: 10.1007/s11307-015-0885-x.

5.
6.

Molecular imaging with a fluorescent antibody targeting carbonic anhydrase IX can successfully detect hypoxic ductal carcinoma in situ of the breast.

van Brussel AS, Adams A, Vermeulen JF, Oliveira S, van der Wall E, Mali WP, van Diest PJ, van Bergen En Henegouwen PM.

Breast Cancer Res Treat. 2013 Jul;140(2):263-72. doi: 10.1007/s10549-013-2635-6. Epub 2013 Jul 17.

PMID:
23860929
7.

Pairwise comparison of 89Zr- and 124I-labeled cG250 based on positron emission tomography imaging and nonlinear immunokinetic modeling: in vivo carbonic anhydrase IX receptor binding and internalization in mouse xenografts of clear-cell renal cell carcinoma.

Cheal SM, Punzalan B, Doran MG, Evans MJ, Osborne JR, Lewis JS, Zanzonico P, Larson SM.

Eur J Nucl Med Mol Imaging. 2014 May;41(5):985-94. doi: 10.1007/s00259-013-2679-1. Epub 2014 Mar 7.

8.

Therapeutic mechanism and efficacy of the antibody-drug conjugate BAY 79-4620 targeting human carbonic anhydrase 9.

Petrul HM, Schatz CA, Kopitz CC, Adnane L, McCabe TJ, Trail P, Ha S, Chang YS, Voznesensky A, Ranges G, Tamburini PP.

Mol Cancer Ther. 2012 Feb;11(2):340-9. doi: 10.1158/1535-7163.MCT-11-0523. Epub 2011 Dec 6.

9.

[111In]-Labeled divalent Fab fragment of chimeric monoclonal antibody cG250 directed against carbonic anhydrase IX.

Chopra A.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2010 Aug 11 [updated 2010 Sep 2].

10.

[111In]-Labeled monovalent Fab fragment of chimeric monoclonal antibody cG250 directed against carbonic anhydrase IX.

Chopra A.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2010 Aug 11 [updated 2010 Sep 2].

11.

[111In]-Labeled chimeric monoclonal antibody cG250 directed against carbonic anhydrase IX.

Chopra A.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2010 Aug 6 [updated 2010 Sep 2].

12.

Imaging of CAIX-expressing xenografts in vivo using 99mTc-HEHEHE-ZCAIX:1 affibody molecule.

Honarvar H, Garousi J, Gunneriusson E, Höidén-Guthenberg I, Altai M, Widström C, Tolmachev V, Frejd FY.

Int J Oncol. 2015 Feb;46(2):513-20. doi: 10.3892/ijo.2014.2782. Epub 2014 Nov 27.

13.

Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy.

McIntyre A, Patiar S, Wigfield S, Li JL, Ledaki I, Turley H, Leek R, Snell C, Gatter K, Sly WS, Vaughan-Jones RD, Swietach P, Harris AL.

Clin Cancer Res. 2012 Jun 1;18(11):3100-11. doi: 10.1158/1078-0432.CCR-11-1877. Epub 2012 Apr 12.

14.

Binding of the phage display derived peptide CaIX-P1 on human colorectal carcinoma cells correlates with the expression of carbonic anhydrase IX.

Askoxylakis V, Ehemann V, Rana S, Krämer S, Rahbari NN, Debus J, Haberkorn U.

Int J Mol Sci. 2012 Oct 11;13(10):13030-48. doi: 10.3390/ijms131013030.

15.

Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors.

Lou Y, McDonald PC, Oloumi A, Chia S, Ostlund C, Ahmadi A, Kyle A, Auf dem Keller U, Leung S, Huntsman D, Clarke B, Sutherland BW, Waterhouse D, Bally M, Roskelley C, Overall CM, Minchinton A, Pacchiano F, Carta F, Scozzafava A, Touisni N, Winum JY, Supuran CT, Dedhar S.

Cancer Res. 2011 May 1;71(9):3364-76. doi: 10.1158/0008-5472.CAN-10-4261. Epub 2011 Mar 17. Erratum in: Cancer Res. 2011 Jun 15;71(12):4325. Cancer Res. 2011 Jul 1;71(13):4733.

16.

Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche.

Lock FE, McDonald PC, Lou Y, Serrano I, Chafe SC, Ostlund C, Aparicio S, Winum JY, Supuran CT, Dedhar S.

Oncogene. 2013 Oct 31;32(44):5210-9. doi: 10.1038/onc.2012.550. Epub 2012 Dec 3.

PMID:
23208505
17.

[(18)F]VM4-037 MicroPET Imaging and Biodistribution of Two In Vivo CAIX-Expressing Tumor Models.

Peeters SG, Dubois L, Lieuwes NG, Laan D, Mooijer M, Schuit RC, Vullo D, Supuran CT, Eriksson J, Windhorst AD, Lambin P.

Mol Imaging Biol. 2015 Oct;17(5):615-9. doi: 10.1007/s11307-015-0831-y.

18.

Comparison of different methods of CAIX quantification in relation to hypoxia in three human head and neck tumor lines.

Troost EG, Bussink J, Kaanders JH, van Eerd J, Peters JP, Rijken PF, Boerman OC, van der Kogel AJ.

Radiother Oncol. 2005 Aug;76(2):194-9.

PMID:
16024110
19.

Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX.

Murri-Plesko MT, Hulikova A, Oosterwijk E, Scott AM, Zortea A, Harris AL, Ritter G, Old L, Bauer S, Swietach P, Renner C.

Eur J Pharmacol. 2011 Apr 25;657(1-3):173-83. doi: 10.1016/j.ejphar.2011.01.063. Epub 2011 Feb 16.

PMID:
21315712
20.

A new peptide ligand for targeting human carbonic anhydrase IX, identified through the phage display technology.

Askoxylakis V, Garcia-Boy R, Rana S, Krämer S, Hebling U, Mier W, Altmann A, Markert A, Debus J, Haberkorn U.

PLoS One. 2010 Dec 31;5(12):e15962. doi: 10.1371/journal.pone.0015962.

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