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Items: 1 to 20 of 113

1.

Functional genomics and cancer drug target discovery.

Moody SE, Boehm JS, Barbie DA, Hahn WC.

Curr Opin Mol Ther. 2010 Jun;12(3):284-93. Review.

PMID:
20521217
2.

Functional genomics to explore cancer cell vulnerabilities.

Kahle KT, Kozono D, Ng K, Hsieh G, Zinn PO, Nitta M, Chen CC.

Neurosurg Focus. 2010 Jan;28(1):E5. doi: 10.3171/2009.10.FOCUS09212.

PMID:
20043720
3.

Targeting tumor suppressor genes for cancer therapy.

Liu Y, Hu X, Han C, Wang L, Zhang X, He X, Lu X.

Bioessays. 2015 Dec;37(12):1277-86. doi: 10.1002/bies.201500093. Epub 2015 Oct 7. Review.

PMID:
26445307
4.

Exploiting genetic complexity in cancer to improve therapeutic strategies.

Garnett MJ, McDermott U.

Drug Discov Today. 2012 Mar;17(5-6):188-93. doi: 10.1016/j.drudis.2012.01.025. Epub 2012 Feb 8.

5.

Highly parallel identification of essential genes in cancer cells.

Luo B, Cheung HW, Subramanian A, Sharifnia T, Okamoto M, Yang X, Hinkle G, Boehm JS, Beroukhim R, Weir BA, Mermel C, Barbie DA, Awad T, Zhou X, Nguyen T, Piqani B, Li C, Golub TR, Meyerson M, Hacohen N, Hahn WC, Lander ES, Sabatini DM, Root DE.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20380-5. doi: 10.1073/pnas.0810485105. Epub 2008 Dec 17.

6.

Oncogenes and tumor suppressor genes: comparative genomics and network perspectives.

Zhu K, Liu Q, Zhou Y, Tao C, Zhao Z, Sun J, Xu H.

BMC Genomics. 2015;16 Suppl 7:S8. doi: 10.1186/1471-2164-16-S7-S8. Epub 2015 Jun 11.

7.

Apply innovative technologies to explore cancer genome.

Shih IeM, Wang TL.

Curr Opin Oncol. 2005 Jan;17(1):33-8. Review.

PMID:
15608510
8.

Integrated genomic and pharmacological approaches to identify synthetic lethal genes as cancer therapeutic targets.

Mizuarai S, Irie H, Schmatz DM, Kotani H.

Curr Mol Med. 2008 Dec;8(8):774-83. Review.

PMID:
19075675
9.

The role of emerging genomics and proteomics technologies in cancer drug target discovery.

Onyango P.

Curr Cancer Drug Targets. 2004 Mar;4(2):111-24. Review.

PMID:
15032664
10.

[The place of functional genomics in oncological research].

Bálint BL, Nagy L.

Magy Onkol. 2013 Mar;57(1):21-5. doi: MagyOnkol.2013.57.1.21. Epub 2013 Feb 10. Review. Hungarian.

11.

Genome-wide approaches for cancer gene discovery.

Lizardi PM, Forloni M, Wajapeyee N.

Trends Biotechnol. 2011 Nov;29(11):558-68. doi: 10.1016/j.tibtech.2011.06.003. Epub 2011 Jul 13. Review.

12.

Database of genomic biomarkers for cancer drugs and clinical targetability in solid tumors.

Dienstmann R, Jang IS, Bot B, Friend S, Guinney J.

Cancer Discov. 2015 Feb;5(2):118-23. doi: 10.1158/2159-8290.CD-14-1118.

13.

Novel clinico-genome network modeling for revolutionizing genotype-phenotype-based personalized cancer care.

Roukos DH.

Expert Rev Mol Diagn. 2010 Jan;10(1):33-48. doi: 10.1586/erm.09.69. Review.

PMID:
20014921
14.

Identification of cancer genes by mutational profiling of tumor genomes.

Benvenuti S, Arena S, Bardelli A.

FEBS Lett. 2005 Mar 21;579(8):1884-90. Review.

15.

Genomic sequencing in cancer.

Tuna M, Amos CI.

Cancer Lett. 2013 Nov 1;340(2):161-70. doi: 10.1016/j.canlet.2012.11.004. Epub 2012 Nov 23. Review.

16.

Cancer target discovery using SAGE.

Porter D, Polyak K.

Expert Opin Ther Targets. 2003 Dec;7(6):759-69. Review.

PMID:
14640911
17.

Genomics of medulloblastoma: from Giemsa-banding to next-generation sequencing in 20 years.

Northcott PA, Rutka JT, Taylor MD.

Neurosurg Focus. 2010 Jan;28(1):E6. doi: 10.3171/2009.10.FOCUS09218. Review.

PMID:
20043721
18.

State of the art discovery with tumor profiling in pediatric oncology.

Carroll WL, Raetz E, Meyer J.

Am Soc Clin Oncol Educ Book. 2015:e601-7. doi: 10.14694/EdBook_AM.2015.35.e601. Review.

19.

Next-generation sequencing technologies for DNA methylation analyses in cancer genomics.

Boerno ST, Grimm C, Lehrach H, Schweiger MR.

Epigenomics. 2010 Apr;2(2):199-207. doi: 10.2217/epi.09.50. Review.

PMID:
22121870
20.

Anticancer drug discovery using chemical genomics.

Sehgal A.

Curr Med Chem. 2003 May;10(9):749-55. Review.

PMID:
12678778

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