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Items: 1 to 20 of 82

1.

ITAM-mediated signaling by the T-cell antigen receptor.

Love PE, Hayes SM.

Cold Spring Harb Perspect Biol. 2010 Jun;2(6):a002485. doi: 10.1101/cshperspect.a002485. Epub 2010 Apr 28. Review.

2.

The 21- and 23-kD forms of TCR zeta are generated by specific ITAM phosphorylations.

van Oers NS, Tohlen B, Malissen B, Moomaw CR, Afendis S, Slaughter CA.

Nat Immunol. 2000 Oct;1(4):322-8.

PMID:
11017104
3.

Role of the multiple T cell receptor (TCR)-zeta chain signaling motifs in selection of the T cell repertoire.

Shores EW, Tran T, Grinberg A, Sommers CL, Shen H, Love PE.

J Exp Med. 1997 Mar 3;185(5):893-900.

4.

Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling.

Qian D, Mollenauer MN, Weiss A.

J Exp Med. 1996 Feb 1;183(2):611-20.

5.

Regulation of TCR signal transduction in murine thymocytes by multiple TCR zeta-chain signaling motifs.

van Oers NS, Love PE, Shores EW, Weiss A.

J Immunol. 1998 Jan 1;160(1):163-70.

6.

T-cell receptor signal transmission: who gives an ITAM?

Pitcher LA, van Oers NS.

Trends Immunol. 2003 Oct;24(10):554-60. Review.

PMID:
14552840
7.

Function of CD3 epsilon-mediated signals in T cell development.

Sommers CL, Dejarnette JB, Huang K, Lee J, El-Khoury D, Shores EW, Love PE.

J Exp Med. 2000 Sep 18;192(6):913-19.

8.

A redundant role of the CD3 gamma-immunoreceptor tyrosine-based activation motif in mature T cell function.

Haks MC, Cordaro TA, van den Brakel JH, Haanen JB, de Vries EF, Borst J, Krimpenfort P, Kruisbeek AM.

J Immunol. 2001 Feb 15;166(4):2576-88.

9.

Comparative study on the effect of phosphorylated TCR zeta chain ITAM sequences on early activation events in Jurkat T cells.

Chiţu V, Fajka-Boja R, Tóth GK, Váradi G, Hegedüs Z, Frankó A, Szücs KS, Monostori E.

Peptides. 2001 Dec;22(12):1963-71.

PMID:
11786178
10.

Contributions of the T cell receptor-associated CD3gamma-ITAM to thymocyte selection.

Haks MC, Pépin E, van den Brakel JH, Smeele SA, Belkowski SM, Kessels HW, Krimpenfort P, Kruisbeek AM.

J Exp Med. 2002 Jul 1;196(1):1-13.

11.

Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosis.

Combadière B, Freedman M, Chen L, Shores EW, Love P, Lenardo MJ.

J Exp Med. 1996 May 1;183(5):2109-17.

13.

Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity.

Holst J, Wang H, Eder KD, Workman CJ, Boyd KL, Baquet Z, Singh H, Forbes K, Chruscinski A, Smeyne R, van Oers NS, Utz PJ, Vignali DA.

Nat Immunol. 2008 Jun;9(6):658-66. doi: 10.1038/ni.1611. Epub 2008 May 11.

PMID:
18469818
14.
15.

Phosphorylated immunoreceptor signaling motifs (ITAMs) exhibit unique abilities to bind and activate Lyn and Syk tyrosine kinases.

Johnson SA, Pleiman CM, Pao L, Schneringer J, Hippen K, Cambier JC.

J Immunol. 1995 Nov 15;155(10):4596-603.

PMID:
7594458
17.

TCR ITAM multiplicity is required for the generation of follicular helper T-cells.

Hwang S, Palin AC, Li L, Song KD, Lee J, Herz J, Tubo N, Chu H, Pepper M, Lesourne R, Zvezdova E, Pinkhasov J, Jenkins MK, McGavern D, Love PE.

Nat Commun. 2015 May 11;6:6982. doi: 10.1038/ncomms7982.

19.

Binding affinities of the SH2 domains of ZAP-70, p56lck and Shc to the zeta chain ITAMs of the T-cell receptor determined by surface plasmon resonance.

Labadia ME, Ingraham RH, Schembri-King J, Morelock MM, Jakes S.

J Leukoc Biol. 1996 May;59(5):740-6.

PMID:
8656061

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