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Items: 1 to 20 of 77


Linking structure to function: Recent lessons from inositol 1,4,5-trisphosphate receptor mutagenesis.

Yule DI, Betzenhauser MJ, Joseph SK.

Cell Calcium. 2010 Jun;47(6):469-79. doi: 10.1016/j.ceca.2010.04.005. Epub 2010 May 26. Review.


Structural and functional conservation of key domains in InsP3 and ryanodine receptors.

Seo MD, Velamakanni S, Ishiyama N, Stathopulos PB, Rossi AM, Khan SA, Dale P, Li C, Ames JB, Ikura M, Taylor CW.

Nature. 2012 Jan 29;483(7387):108-12. doi: 10.1038/nature10751.


InsP3R-associated cGMP kinase substrate determines inositol 1,4,5-trisphosphate receptor susceptibility to phosphoregulation by cyclic nucleotide-dependent kinases.

Masuda W, Betzenhauser MJ, Yule DI.

J Biol Chem. 2010 Nov 26;285(48):37927-38. doi: 10.1074/jbc.M110.168989. Epub 2010 Sep 27.


Tyr-167/Trp-168 in type 1/3 inositol 1,4,5-trisphosphate receptor mediates functional coupling between ligand binding and channel opening.

Yamazaki H, Chan J, Ikura M, Michikawa T, Mikoshiba K.

J Biol Chem. 2010 Nov 12;285(46):36081-91. doi: 10.1074/jbc.M110.140129. Epub 2010 Sep 2.


Regulation of single inositol 1,4,5-trisphosphate receptor channel activity by protein kinase A phosphorylation.

Wagner LE 2nd, Joseph SK, Yule DI.

J Physiol. 2008 Aug 1;586(15):3577-96. doi: 10.1113/jphysiol.2008.152314. Epub 2008 Jun 5.


Association of type 1 inositol 1,4,5-trisphosphate receptor with AKAP9 (Yotiao) and protein kinase A.

Tu H, Tang TS, Wang Z, Bezprozvanny I.

J Biol Chem. 2004 Apr 30;279(18):19375-82. Epub 2004 Feb 24.


Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating.

Chan J, Yamazaki H, Ishiyama N, Seo MD, Mal TK, Michikawa T, Mikoshiba K, Ikura M.

J Biol Chem. 2010 Nov 12;285(46):36092-9. doi: 10.1074/jbc.M110.140160. Epub 2010 Sep 15.


ATP-dependent adenophostin activation of inositol 1,4,5-trisphosphate receptor channel gating: kinetic implications for the durations of calcium puffs in cells.

Mak DO, McBride S, Foskett JK.

J Gen Physiol. 2001 Apr;117(4):299-314. Erratum in: J Gen Physiol 2001 Apr;117(4):369.


Carboxyl-terminal sequences critical for inositol 1,4,5-trisphosphate receptor subunit assembly.

Galvan DL, Mignery GA.

J Biol Chem. 2002 Dec 13;277(50):48248-60. Epub 2002 Oct 10.


Identification of functionally critical residues in the channel domain of inositol trisphosphate receptors.

Bhanumathy C, da Fonseca PC, Morris EP, Joseph SK.

J Biol Chem. 2012 Dec 21;287(52):43674-84. doi: 10.1074/jbc.M112.415786. Epub 2012 Oct 18.


Molecular determinants of the interaction between the inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate (IRAG) and cGMP kinase Ibeta.

Ammendola A, Geiselhöringer A, Hofmann F, Schlossmann J.

J Biol Chem. 2001 Jun 29;276(26):24153-9. Epub 2001 Apr 17.


Location of the permeation pathway in the recombinant type 1 inositol 1,4,5-trisphosphate receptor.

Ramos-Franco J, Galvan D, Mignery GA, Fill M.

J Gen Physiol. 1999 Aug;114(2):243-50.


Bi-directional signalling from the InsP3 receptor: regulation by calcium and accessory factors.

Roderick HL, Bootman MD.

Biochem Soc Trans. 2003 Oct;31(Pt 5):950-3. Review.


A role for phosphorylation of inositol 1,4,5-trisphosphate receptors in defining calcium signals induced by Peptide agonists in pancreatic acinar cells.

Straub SV, Giovannucci DR, Bruce JI, Yule DI.

J Biol Chem. 2002 Aug 30;277(35):31949-56. Epub 2002 Jun 13.

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