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Items: 1 to 20 of 118

1.

Structure-function relationships of human aromatase cytochrome P-450 using molecular modeling and site-directed mutagenesis.

Graham-Lorence S, Khalil MW, Lorence MC, Mendelson CR, Simpson ER.

J Biol Chem. 1991 Jun 25;266(18):11939-46.

2.

Identification of thromboxane A2 synthase active site residues by molecular modeling-guided site-directed mutagenesis.

Wang LH, Matijevic-Aleksic N, Hsu PY, Ruan KH, Wu KK, Kulmacz RJ.

J Biol Chem. 1996 Aug 16;271(33):19970-5.

3.

Structure-function studies of human aromatase.

Chen S, Zhou D, Swiderek KM, Kadohama N, Osawa Y, Hall PF.

J Steroid Biochem Mol Biol. 1993 Mar;44(4-6):347-56. Review.

PMID:
8476748
4.

A site-directed mutagenesis study of human placental aromatase.

Zhou DJ, Korzekwa KR, Poulos T, Chen SA.

J Biol Chem. 1992 Jan 15;267(2):762-8.

5.

Mutagenesis study at a postulated hydrophobic region near the active site of aromatase cytochrome P450.

Zhou D, Cam LL, Laughton CA, Korzekwa KR, Chen S.

J Biol Chem. 1994 Jul 29;269(30):19501-8.

6.

Analysis of the catalytic activity of human factor XIIIa by site-directed mutagenesis.

Hettasch JM, Greenberg CS.

J Biol Chem. 1994 Nov 11;269(45):28309-13.

7.

Use of molecular probes to study regulation of aromatase cytochrome P-450.

Mendelson CR, Means GD, Mahendroo MS, Corbin CJ, Steinkampf MP, Graham-Lorence S, Simpson ER.

Biol Reprod. 1990 Jan;42(1):1-10.

8.

Functional ovarian and placental isoforms of porcine aromatase.

Corbin CJ, Khalil MW, Conley AJ.

Mol Cell Endocrinol. 1995 Aug 30;113(1):29-37.

PMID:
8674811
9.

Site-directed mutagenesis of the putative distal helix of peroxygenase cytochrome P450.

Matsunaga I, Ueda A, Sumimoto T, Ichihara K, Ayata M, Ogura H.

Arch Biochem Biophys. 2001 Oct 1;394(1):45-53.

PMID:
11566026
10.
12.

A detailed molecular model for human aromatase.

Laughton CA, Zvelebil MJ, Neidle S.

J Steroid Biochem Mol Biol. 1993 Mar;44(4-6):399-407.

PMID:
8476753
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Determinants of the substrate specificity of human cytochrome P-450 CYP2D6: design and construction of a mutant with testosterone hydroxylase activity.

Smith G, Modi S, Pillai I, Lian LY, Sutcliffe MJ, Pritchard MP, Friedberg T, Roberts GC, Wolf CR.

Biochem J. 1998 May 1;331 ( Pt 3):783-92.

19.

Structure/function studies of human immunodeficiency virus type 1 reverse transcriptase. Alanine scanning mutagenesis of an alpha-helix in the thumb subdomain.

Beard WA, Stahl SJ, Kim HR, Bebenek K, Kumar A, Strub MP, Becerra SP, Kunkel TA, Wilson SH.

J Biol Chem. 1994 Nov 11;269(45):28091-7.

20.
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