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Items: 1 to 20 of 180

1.

Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis.

Wegner N, Wait R, Sroka A, Eick S, Nguyen KA, Lundberg K, Kinloch A, Culshaw S, Potempa J, Venables PJ.

Arthritis Rheum. 2010 Sep;62(9):2662-72. doi: 10.1002/art.27552.

2.

Porphyromonas gingivalis peptidylarginine deiminase substrate specificity.

Abdullah SN, Farmer EA, Spargo L, Logan R, Gully N.

Anaerobe. 2013 Oct;23:102-8. doi: 10.1016/j.anaerobe.2013.07.001. Epub 2013 Jul 13.

PMID:
23856045
3.

Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis.

Montgomery AB, Kopec J, Shrestha L, Thezenas ML, Burgess-Brown NA, Fischer R, Yue WW, Venables PJ.

Ann Rheum Dis. 2016 Jun;75(6):1255-61. doi: 10.1136/annrheumdis-2015-207656. Epub 2015 Jul 24.

4.

Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis.

Wegner N, Lundberg K, Kinloch A, Fisher B, Malmström V, Feldmann M, Venables PJ.

Immunol Rev. 2010 Jan;233(1):34-54. doi: 10.1111/j.0105-2896.2009.00850.x. Review.

PMID:
20192991
5.

Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis.

Quirke AM, Lugli EB, Wegner N, Hamilton BC, Charles P, Chowdhury M, Ytterberg AJ, Zubarev RA, Potempa J, Culshaw S, Guo Y, Fisher BA, Thiele G, Mikuls TR, Venables PJ.

Ann Rheum Dis. 2014 Jan;73(1):263-9. doi: 10.1136/annrheumdis-2012-202726. Epub 2013 Mar 5.

6.

Defining the role of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) in rheumatoid arthritis through the study of PPAD biology.

Konig MF, Paracha AS, Moni M, Bingham CO 3rd, Andrade F.

Ann Rheum Dis. 2015 Nov;74(11):2054-61. doi: 10.1136/annrheumdis-2014-205385. Epub 2014 May 26.

7.

Porphyromonas gingivalis may play an important role in the pathogenesis of periodontitis-associated rheumatoid arthritis.

Liao F, Li Z, Wang Y, Shi B, Gong Z, Cheng X.

Med Hypotheses. 2009 Jun;72(6):732-5. doi: 10.1016/j.mehy.2008.12.040. Epub 2009 Feb 25.

PMID:
19246161
8.

Antibodies to citrullinated alpha-enolase peptide 1 are specific for rheumatoid arthritis and cross-react with bacterial enolase.

Lundberg K, Kinloch A, Fisher BA, Wegner N, Wait R, Charles P, Mikuls TR, Venables PJ.

Arthritis Rheum. 2008 Oct;58(10):3009-19. doi: 10.1002/art.23936.

9.

Identification of citrullinated alpha-enolase as a candidate autoantigen in rheumatoid arthritis.

Kinloch A, Tatzer V, Wait R, Peston D, Lundberg K, Donatien P, Moyes D, Taylor PC, Venables PJ.

Arthritis Res Ther. 2005;7(6):R1421-9. Epub 2005 Oct 19.

10.

Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis.

Kinloch A, Lundberg K, Wait R, Wegner N, Lim NH, Zendman AJ, Saxne T, Malmström V, Venables PJ.

Arthritis Rheum. 2008 Aug;58(8):2287-95. doi: 10.1002/art.23618.

11.

Porphyromonas gingivalis facilitates the development and progression of destructive arthritis through its unique bacterial peptidylarginine deiminase (PAD).

Maresz KJ, Hellvard A, Sroka A, Adamowicz K, Bielecka E, Koziel J, Gawron K, Mizgalska D, Marcinska KA, Benedyk M, Pyrc K, Quirke AM, Jonsson R, Alzabin S, Venables PJ, Nguyen KA, Mydel P, Potempa J.

PLoS Pathog. 2013 Sep;9(9):e1003627. doi: 10.1371/journal.ppat.1003627. Epub 2013 Sep 12.

12.

The association between rheumatoid arthritis and periodontitis.

Leech MT, Bartold PM.

Best Pract Res Clin Rheumatol. 2015 Apr;29(2):189-201. doi: 10.1016/j.berh.2015.03.001. Epub 2015 May 1. Review.

PMID:
26362738
13.

The peptidylarginine deiminase gene is a conserved feature of Porphyromonas gingivalis.

Gabarrini G, de Smit M, Westra J, Brouwer E, Vissink A, Zhou K, Rossen JW, Stobernack T, van Dijl JM, van Winkelhoff AJ.

Sci Rep. 2015 Sep 25;5:13936. doi: 10.1038/srep13936.

14.

Rheumatoid arthritis-specific autoantibodies to peptidyl arginine deiminase type 4 inhibit citrullination of fibrinogen.

Auger I, Martin M, Balandraud N, Roudier J.

Arthritis Rheum. 2010 Jan;62(1):126-31. doi: 10.1002/art.27230.

15.

Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis?

Mangat P, Wegner N, Venables PJ, Potempa J.

Arthritis Res Ther. 2010;12(3):209. doi: 10.1186/ar3000. Epub 2010 Jun 2. Review.

16.

Periodontitis in RA-the citrullinated enolase connection.

Lundberg K, Wegner N, Yucel-Lindberg T, Venables PJ.

Nat Rev Rheumatol. 2010 Dec;6(12):727-30. doi: 10.1038/nrrheum.2010.139. Epub 2010 Sep 7. Review.

PMID:
20820197
17.

Peptidylarginine deiminase modulates the physiological roles of enolase via citrullination: links between altered multifunction of enolase and neurodegenerative diseases.

Jang B, Jeon YC, Choi JK, Park M, Kim JI, Ishigami A, Maruyama N, Carp RI, Kim YS, Choi EK.

Biochem J. 2012 Jul 15;445(2):183-92. doi: 10.1042/BJ20120025.

PMID:
22551201
18.

Effect of Porphyromonas gingivalis on citrullination of proteins by macrophages in vitro.

Marchant C, Smith MD, Proudman S, Haynes DR, Bartold PM.

J Periodontol. 2013 Sep;84(9):1272-80. doi: 10.1902/jop.2012.120103. Epub 2012 Oct 29.

PMID:
23106505
19.

Immunization with Porphyromonas gingivalis enolase induces autoimmunity to mammalian α-enolase and arthritis in DR4-IE-transgenic mice.

Kinloch AJ, Alzabin S, Brintnell W, Wilson E, Barra L, Wegner N, Bell DA, Cairns E, Venables PJ.

Arthritis Rheum. 2011 Dec;63(12):3818-23. doi: 10.1002/art.30639.

20.

Periodontal treatment decreases levels of antibodies to Porphyromonas gingivalis and citrulline in patients with rheumatoid arthritis and periodontitis.

Okada M, Kobayashi T, Ito S, Yokoyama T, Abe A, Murasawa A, Yoshie H.

J Periodontol. 2013 Dec;84(12):e74-84. doi: 10.1902/jop.2013.130079. Epub 2013 May 23.

PMID:
23701010

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