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Items: 1 to 20 of 248

1.

Experimental colitis triggers the release of substance P and calcitonin gene-related peptide in the urinary bladder via TRPV1 signaling pathways.

Pan XQ, Gonzalez JA, Chang S, Chacko S, Wein AJ, Malykhina AP.

Exp Neurol. 2010 Oct;225(2):262-73. doi: 10.1016/j.expneurol.2010.05.012. Epub 2010 May 23.

2.

Colonic inflammation up-regulates voltage-gated sodium channels in bladder sensory neurons via activation of peripheral transient potential vanilloid 1 receptors.

Lei Q, Malykhina AP.

Neurogastroenterol Motil. 2012 Jun;24(6):575-85, e257. doi: 10.1111/j.1365-2982.2012.01910.x. Epub 2012 Mar 15.

3.

The proximodistal aggravation of colitis depends on substance P released from TRPV1-expressing sensory neurons.

Engel MA, Khalil M, Mueller-Tribbensee SM, Becker C, Neuhuber WL, Neurath MF, Reeh PW.

J Gastroenterol. 2012 Mar;47(3):256-65. doi: 10.1007/s00535-011-0495-6. Epub 2011 Nov 12.

PMID:
22080974
4.

Differential effects of intravesical resiniferatoxin on excitability of bladder spinal neurons upon colon-bladder cross-sensitization.

Malykhina AP, Qin C, Lei Q, Pan XQ, Greenwood-Van Meerveld B, Foreman RD.

Brain Res. 2013 Jan 23;1491:213-24. doi: 10.1016/j.brainres.2012.11.003. Epub 2012 Nov 9.

5.

TRPA1 and substance P mediate colitis in mice.

Engel MA, Leffler A, Niedermirtl F, Babes A, Zimmermann K, Filipović MR, Izydorczyk I, Eberhardt M, Kichko TI, Mueller-Tribbensee SM, Khalil M, Siklosi N, Nau C, Ivanović-Burmazović I, Neuhuber WL, Becker C, Neurath MF, Reeh PW.

Gastroenterology. 2011 Oct;141(4):1346-58. doi: 10.1053/j.gastro.2011.07.002. Epub 2011 Jul 18.

PMID:
21763243
6.

Acute colonic inflammation triggers detrusor instability via activation of TRPV1 receptors in a rat model of pelvic organ cross-sensitization.

Asfaw TS, Hypolite J, Northington GM, Arya LA, Wein AJ, Malykhina AP.

Am J Physiol Regul Integr Comp Physiol. 2011 Jun;300(6):R1392-400. doi: 10.1152/ajpregu.00804.2010. Epub 2011 Apr 6.

7.

Estrous cycle dependent fluctuations of regulatory neuropeptides in the lower urinary tract of female rats upon colon-bladder cross-sensitization.

Pan XQ, Malykhina AP.

PLoS One. 2014 May 1;9(5):e94872. doi: 10.1371/journal.pone.0094872. eCollection 2014.

8.

Up-regulation of brain-derived neurotrophic factor in primary afferent pathway regulates colon-to-bladder cross-sensitization in rat.

Xia CM, Gulick MA, Yu SJ, Grider JR, Murthy KS, Kuemmerle JF, Akbarali HI, Qiao LY.

J Neuroinflammation. 2012 Feb 15;9:30. doi: 10.1186/1742-2094-9-30.

9.

Pelvic organ cross-sensitization to enhance bladder and urethral pain behaviors in rats with experimental colitis.

Yoshikawa S, Kawamorita N, Oguchi T, Funahashi Y, Tyagi P, Chancellor MB, Yoshimura N.

Neuroscience. 2015 Jan 22;284:422-9. doi: 10.1016/j.neuroscience.2014.08.064. Epub 2014 Oct 15.

PMID:
25445197
10.

TRPV1 receptor signaling mediates afferent nerve sensitization during colitis-induced motility disorders in rats.

De Schepper HU, De Man JG, Ruyssers NE, Deiteren A, Van Nassauw L, Timmermans JP, Martinet W, Herman AG, Pelckmans PA, De Winter BY.

Am J Physiol Gastrointest Liver Physiol. 2008 Jan;294(1):G245-53. Epub 2007 Nov 8.

11.

Colitis induces calcitonin gene-related peptide expression and Akt activation in rat primary afferent pathways.

Qiao LY, Grider JR.

Exp Neurol. 2009 Sep;219(1):93-103. doi: 10.1016/j.expneurol.2009.04.026. Epub 2009 May 5.

13.

TRPV1, NK1 receptor and substance P immunoreactivity and gene expression in the rat lumbosacral spinal cord and urinary bladder after systemic, low dose vanilloid administration.

Heng YJ, Saunders CI, Kunde DA, Geraghty DP.

Regul Pept. 2011 Apr 11;167(2-3):250-8. doi: 10.1016/j.regpep.2011.02.004. Epub 2011 Feb 15.

PMID:
21329730
14.

Lack of transient receptor potential vanilloid 1 channel modulates the development of neurogenic bladder dysfunction induced by cross-sensitization in afferent pathways.

Lei Q, Pan XQ, Villamor AN, Asfaw TS, Chang S, Zderic SA, Malykhina AP.

J Neuroinflammation. 2013 Jan 11;10:3. doi: 10.1186/1742-2094-10-3.

15.

Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis.

Wick EC, Hoge SG, Grahn SW, Kim E, Divino LA, Grady EF, Bunnett NW, Kirkwood KS.

Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G959-69. Epub 2006 Jan 6.

16.
18.

Opposite effects of substance P and calcitonin gene-related peptide in oxazolone colitis.

Engel MA, Khalil M, Siklosi N, Mueller-Tribbensee SM, Neuhuber WL, Neurath MF, Becker C, Reeh PW.

Dig Liver Dis. 2012 Jan;44(1):24-9. doi: 10.1016/j.dld.2011.08.030. Epub 2011 Oct 22.

PMID:
22018693
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