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Items: 1 to 20 of 102

1.

Filaggrin null mutations associate with increased frequencies of allergen-specific CD4+ T-helper 2 cells in patients with atopic eczema.

McPherson T, Sherman VJ, Aslam A, Crack L, Chan H, Lloyd-Lavery A, Jones L, Ardern-Jones M, Ogg G.

Br J Dermatol. 2010 Sep;163(3):544-9. doi: 10.1111/j.1365-2133.2010.09866.x. Epub 2010 Jul 28.

PMID:
20500796
2.

Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march.

Marenholz I, Nickel R, Rüschendorf F, Schulz F, Esparza-Gordillo J, Kerscher T, Grüber C, Lau S, Worm M, Keil T, Kurek M, Zaluga E, Wahn U, Lee YA.

J Allergy Clin Immunol. 2006 Oct;118(4):866-71. Epub 2006 Sep 1.

PMID:
17030239
3.

Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children.

Brown SJ, Relton CL, Liao H, Zhao Y, Sandilands A, McLean WH, Cordell HJ, Reynolds NJ.

Br J Dermatol. 2009 Oct;161(4):884-9. doi: 10.1111/j.1365-2133.2009.09339.x. Epub 2009 Jun 11.

4.

Filaggrin null mutations and childhood atopic eczema: a population-based case-control study.

Brown SJ, Relton CL, Liao H, Zhao Y, Sandilands A, Wilson IJ, Burn J, Reynolds NJ, McLean WH, Cordell HJ.

J Allergy Clin Immunol. 2008 Apr;121(4):940-46.e3. doi: 10.1016/j.jaci.2008.01.013. Epub 2008 Mar 4.

PMID:
18313126
5.

Loss-of-function variants of the filaggrin gene are associated with atopic eczema and associated phenotypes in Swedish families.

Ekelund E, Liedén A, Link J, Lee SP, D'Amato M, Palmer CN, Kockum I, Bradley M.

Acta Derm Venereol. 2008;88(1):15-9. doi: 10.2340/00015555-0383.

6.

The burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort study.

Henderson J, Northstone K, Lee SP, Liao H, Zhao Y, Pembrey M, Mukhopadhyay S, Smith GD, Palmer CN, McLean WH, Irvine AD.

J Allergy Clin Immunol. 2008 Apr;121(4):872-7.e9. doi: 10.1016/j.jaci.2008.01.026. Epub 2008 Mar 5.

PMID:
18325573
7.

Anti-lymphocyte function associated antigen-1 inhibits T-helper 2 function of human allergen-specific CD4+ T cells.

Ardern-Jones MR, Black AP, Ogg GS.

Br J Dermatol. 2008 Mar;158(3):456-62. doi: 10.1111/j.1365-2133.2007.08393.x. Epub 2008 Jan 17.

PMID:
18205875
8.

Filaggrin mutations, atopic eczema, hay fever, and asthma in children.

Weidinger S, O'Sullivan M, Illig T, Baurecht H, Depner M, Rodriguez E, Ruether A, Klopp N, Vogelberg C, Weiland SK, McLean WH, von Mutius E, Irvine AD, Kabesch M.

J Allergy Clin Immunol. 2008 May;121(5):1203-1209.e1. doi: 10.1016/j.jaci.2008.02.014. Epub 2008 Apr 8.

PMID:
18396323
9.

Atopic eczema and the filaggrin story.

Brown SJ, Irvine AD.

Semin Cutan Med Surg. 2008 Jun;27(2):128-37. doi: 10.1016/j.sder.2008.04.001. Review.

PMID:
18620134
10.
11.

Cellular and molecular mechanisms of IL-5 synthesis in atopic diseases: a study with allergen-specific human helper T cells.

Mori A, Kaminuma O, Suko M, Mikami T, Nishizaki Y, Ohmura T, Hoshino A, Asakura Y, Miyazawa K, Ando T, Okumura Y, Yamamoto K, Okudaira H.

J Allergy Clin Immunol. 1997 Dec;100(6 Pt 2):S56-64.

PMID:
9440546
12.

Filaggrin null mutations increase the risk and persistence of hand eczema in subjects with atopic dermatitis: results from a general population study.

Thyssen JP, Carlsen BC, Menné T, Linneberg A, Nielsen NH, Meldgaard M, Szecsi PB, Stender S, Johansen JD.

Br J Dermatol. 2010 Jul;163(1):115-20. doi: 10.1111/j.1365-2133.2010.09822.x. Epub 2010 Apr 23.

PMID:
20426775
13.

Classification of atopic hand eczema and the filaggrin mutations.

Giwercman C, Lerbaek A, Bisgaard H, Menné T.

Contact Dermatitis. 2008 Nov;59(5):257-60. doi: 10.1111/j.1600-0536.2008.01426.x. Review.

PMID:
18976374
14.

Atopic asthma: differential activation phenotypes among memory T helper cells.

Lara-Marquez ML, Moan MJ, Cartwright S, Listman J, Israel E, Perkins DL, Christiani DC, Finn PW.

Clin Exp Allergy. 2001 Aug;31(8):1232-41.

PMID:
11529893
15.

Frequencies of circulating allergen-specific T cells temporally associate with longitudinal changes in severity of cutaneous atopic disease.

McPherson T, Aslam A, Crack L, Chan H, Jones L, Ogg G.

Clin Exp Dermatol. 2010 Oct;35(7):786-8. doi: 10.1111/j.1365-2230.2010.03791.x.

PMID:
20184609
16.

Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease.

Rodríguez E, Baurecht H, Herberich E, Wagenpfeil S, Brown SJ, Cordell HJ, Irvine AD, Weidinger S.

J Allergy Clin Immunol. 2009 Jun;123(6):1361-70.e7. doi: 10.1016/j.jaci.2009.03.036.

PMID:
19501237
17.

Null mutations in the filaggrin gene (FLG) determine major susceptibility to early-onset atopic dermatitis that persists into adulthood.

Barker JN, Palmer CN, Zhao Y, Liao H, Hull PR, Lee SP, Allen MH, Meggitt SJ, Reynolds NJ, Trembath RC, McLean WH.

J Invest Dermatol. 2007 Mar;127(3):564-7. Epub 2006 Sep 21.

18.

The eczema risk variant on chromosome 11q13 (rs7927894) in the population-based ALSPAC cohort: a novel susceptibility factor for asthma and hay fever.

Marenholz I, Bauerfeind A, Esparza-Gordillo J, Kerscher T, Granell R, Nickel R, Lau S, Henderson J, Lee YA.

Hum Mol Genet. 2011 Jun 15;20(12):2443-9. doi: 10.1093/hmg/ddr117. Epub 2011 Mar 23.

PMID:
21429916
19.

Filaggrin loss-of-function variants are associated with atopic comorbidity in pediatric inflammatory bowel disease.

Van Limbergen J, Russell RK, Nimmo ER, Zhao Y, Liao H, Drummond HE, Davies G, Gillett PM, McGrogan P, Bisset WM, Mahdi G, Wilson DC, Brown SJ, McLean WH, Satsangi J.

Inflamm Bowel Dis. 2009 Oct;15(10):1492-8. doi: 10.1002/ibd.20926.

PMID:
19408338
20.

Filaggrin null mutations are associated with increased asthma severity in children and young adults.

Palmer CN, Ismail T, Lee SP, Terron-Kwiatkowski A, Zhao Y, Liao H, Smith FJ, McLean WH, Mukhopadhyay S.

J Allergy Clin Immunol. 2007 Jul;120(1):64-8. Epub 2007 May 25.

PMID:
17531295

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