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Items: 1 to 20 of 100

1.

Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects.

Naylor JC, Kilts JD, Hulette CM, Steffens DC, Blazer DG, Ervin JF, Strauss JL, Allen TB, Massing MW, Payne VM, Youssef NA, Shampine LJ, Marx CE.

Biochim Biophys Acta. 2010 Aug;1801(8):951-9. doi: 10.1016/j.bbalip.2010.05.006. Epub 2010 May 19.

2.

The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease.

Marx CE, Trost WT, Shampine LJ, Stevens RD, Hulette CM, Steffens DC, Ervin JF, Butterfield MI, Blazer DG, Massing MW, Lieberman JA.

Biol Psychiatry. 2006 Dec 15;60(12):1287-94. Epub 2006 Sep 25.

PMID:
16997284
3.

Cerebrospinal fluid dehydroepiandrosterone levels are correlated with brain dehydroepiandrosterone levels, elevated in Alzheimer's disease, and related to neuropathological disease stage.

Naylor JC, Hulette CM, Steffens DC, Shampine LJ, Ervin JF, Payne VM, Massing MW, Kilts JD, Strauss JL, Calhoun PS, Calnaido RP, Blazer DG, Lieberman JA, Madison RD, Marx CE.

J Clin Endocrinol Metab. 2008 Aug;93(8):3173-8. doi: 10.1210/jc.2007-1229. Epub 2008 May 13.

4.

Allopregnanolone and dehydroepiandrosterone response to corticotropin-releasing factor in patients suffering from Alzheimer's disease and vascular dementia.

Bernardi F, Lanzone A, Cento RM, Spada RS, Pezzani I, Genazzani AD, Luisi S, Luisi M, Petraglia F, Genazzani AR.

Eur J Endocrinol. 2000 May;142(5):466-71.

5.

Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients.

Weill-Engerer S, David JP, Sazdovitch V, Liere P, Eychenne B, Pianos A, Schumacher M, Delacourte A, Baulieu EE, Akwa Y.

J Clin Endocrinol Metab. 2002 Nov;87(11):5138-43.

PMID:
12414884
6.

Cortical Transcriptional Profiles in APOE4 Carriers with Alzheimer's Disease: Patterns of Protection and Degeneration.

Conejero-Goldberg C, Hyde TM, Chen S, Herman MM, Kleinman JE, Davies P, Goldberg TE.

J Alzheimers Dis. 2015;48(4):969-78. doi: 10.3233/JAD-150345.

PMID:
26444771
7.

Altered NCAM expression associated with the cholinergic system in Alzheimer's disease.

Aisa B, Gil-Bea FJ, Solas M, García-Alloza M, Chen CP, Lai MK, Francis PT, Ramírez MJ.

J Alzheimers Dis. 2010;20(2):659-68. doi: 10.3233/JAD-2010-1398.

PMID:
20164549
8.

Exploratory investigation of biomarker candidates for suicide in schizophrenia and bipolar disorder.

Youssef NA, Bradford DW, Kilts JD, Szabo ST, Naylor JC, Allen TB, Strauss JL, Hamer RM, Brancu M, Shampine LJ, Marx CE.

Crisis. 2015;36(1):46-54. doi: 10.1027/0227-5910/a000280. Erratum in: Crisis. 2016;37(1):77. Brunca, Mira [corrected to Brancu, Mira].

PMID:
25410258
9.

Greater medial temporal hypometabolism and lower cortical amyloid burden in ApoE4-positive AD patients.

Lehmann M, Ghosh PM, Madison C, Karydas A, Coppola G, O'Neil JP, Huang Y, Miller BL, Jagust WJ, Rabinovici GD.

J Neurol Neurosurg Psychiatry. 2014 Mar;85(3):266-73. doi: 10.1136/jnnp-2013-305858. Epub 2013 Aug 21.

10.

APOE4 is associated with greater atrophy of the hippocampal formation in Alzheimer's disease.

Pievani M, Galluzzi S, Thompson PM, Rasser PE, Bonetti M, Frisoni GB.

Neuroimage. 2011 Apr 1;55(3):909-19. doi: 10.1016/j.neuroimage.2010.12.081. Epub 2011 Jan 9.

PMID:
21224004
11.

Early neuropathological Alzheimer's changes in aged individuals are accompanied by decreased cerebrospinal fluid melatonin levels.

Zhou JN, Liu RY, Kamphorst W, Hofman MA, Swaab DF.

J Pineal Res. 2003 Sep;35(2):125-30.

PMID:
12887656
12.

Decreased levels of BDNF protein in Alzheimer temporal cortex are independent of BDNF polymorphisms.

Lee J, Fukumoto H, Orne J, Klucken J, Raju S, Vanderburg CR, Irizarry MC, Hyman BT, Ingelsson M.

Exp Neurol. 2005 Jul;194(1):91-6.

PMID:
15899246
13.

Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma.

Ahboucha S, Pomier-Layrargues G, Mamer O, Butterworth RF.

Neurochem Int. 2006 Sep;49(4):372-8. Epub 2006 Mar 24.

PMID:
16563564
14.

Allopregnanolone as regenerative therapeutic for Alzheimer's disease: translational development and clinical promise.

Irwin RW, Brinton RD.

Prog Neurobiol. 2014 Feb;113:40-55. doi: 10.1016/j.pneurobio.2013.08.004. Epub 2013 Sep 14. Review.

PMID:
24044981
15.

Neuronal expression of F-box and leucine-rich-repeat protein 2 decreases over Braak stages in the brains of Alzheimer's disease patients.

Watanabe T, von der Kammer H, Wang X, Shintani Y, Horiguchi T.

Neurodegener Dis. 2013;11(1):1-12. Epub 2012 Mar 27.

PMID:
22455980
16.

Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype.

Berg L, McKeel DW Jr, Miller JP, Storandt M, Rubin EH, Morris JC, Baty J, Coats M, Norton J, Goate AM, Price JL, Gearing M, Mirra SS, Saunders AM.

Arch Neurol. 1998 Mar;55(3):326-35.

PMID:
9520006
17.

Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease.

Mufson EJ, Wuu J, Counts SE, Nykjaer A.

Neurosci Lett. 2010 Mar 8;471(3):129-33. doi: 10.1016/j.neulet.2010.01.023. Epub 2010 Jan 18.

18.

Microvascular injury and blood-brain barrier leakage in Alzheimer's disease.

Zipser BD, Johanson CE, Gonzalez L, Berzin TM, Tavares R, Hulette CM, Vitek MP, Hovanesian V, Stopa EG.

Neurobiol Aging. 2007 Jul;28(7):977-86. Epub 2006 Jun 16.

PMID:
16782234
19.

Clusterin (apolipoprotein J) protein levels are increased in hippocampus and in frontal cortex in Alzheimer's disease.

Lidström AM, Bogdanovic N, Hesse C, Volkman I, Davidsson P, Blennow K.

Exp Neurol. 1998 Dec;154(2):511-21.

PMID:
9878186
20.

Apolipoprotein E allelotype is associated with neuropathological findings in Alzheimer's disease.

Kumar NT, Liestøl K, Løberg EM, Reims HM, Mæhlen J.

Virchows Arch. 2015 Aug;467(2):225-35. doi: 10.1007/s00428-015-1772-1. Epub 2015 Apr 22.

PMID:
25898889

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