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Items: 1 to 20 of 77

1.

Bone morphogenetic protein-2 and -6 heterodimer illustrates the nature of ligand-receptor assembly.

Isaacs MJ, Kawakami Y, Allendorph GP, Yoon BH, Izpisua Belmonte JC, Choe S.

Mol Endocrinol. 2010 Jul;24(7):1469-77. doi: 10.1210/me.2009-0496. Epub 2010 May 19.

2.

Crystal structure of BMP-9 and functional interactions with pro-region and receptors.

Brown MA, Zhao Q, Baker KA, Naik C, Chen C, Pukac L, Singh M, Tsareva T, Parice Y, Mahoney A, Roschke V, Sanyal I, Choe S.

J Biol Chem. 2005 Jul 1;280(26):25111-8. Epub 2005 Apr 25.

3.

Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.

Kotzsch A, Nickel J, Seher A, Heinecke K, van Geersdaele L, Herrmann T, Sebald W, Mueller TD.

J Biol Chem. 2008 Feb 29;283(9):5876-87. Epub 2007 Dec 26.

4.

BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors.

Allendorph GP, Isaacs MJ, Kawakami Y, Izpisua Belmonte JC, Choe S.

Biochemistry. 2007 Oct 30;46(43):12238-47. Epub 2007 Oct 9. Erratum in: Biochemistry. 2007 Oct 30;46(43):12246.

PMID:
17924656
5.

Formation of stable homomeric and transient heteromeric bone morphogenetic protein (BMP) receptor complexes regulates Smad protein signaling.

Marom B, Heining E, Knaus P, Henis YI.

J Biol Chem. 2011 Jun 3;286(22):19287-96. doi: 10.1074/jbc.M110.210377. Epub 2011 Apr 6.

6.

Temporal regulation of BMP2, BMP6, BMP15, GDF9, BMPR1A, BMPR1B, BMPR2 and TGFBR1 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.

Paradis F, Novak S, Murdoch GK, Dyck MK, Dixon WT, Foxcroft GR.

Reproduction. 2009 Jul;138(1):115-29. doi: 10.1530/REP-08-0538. Epub 2009 Apr 9.

7.

Identification of the ligand-binding site of the BMP type IA receptor for BMP-4.

Hatta T, Konishi H, Katoh E, Natsume T, Ueno N, Kobayashi Y, Yamazaki T.

Biopolymers. 2000;55(5):399-406.

PMID:
11241215
8.

Crystal structure of the BMP-2-BRIA ectodomain complex.

Kirsch T, Sebald W, Dreyer MK.

Nat Struct Biol. 2000 Jun;7(6):492-6.

PMID:
10881198
9.

A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.

Weber D, Kotzsch A, Nickel J, Harth S, Seher A, Mueller U, Sebald W, Mueller TD.

BMC Struct Biol. 2007 Feb 12;7:6.

10.

Bone morphogenetic protein 2 stimulates noncanonical SMAD2/3 signaling via the BMP type 1A receptor in gonadotrope-like cells: implications for FSH synthesis.

Wang Y, Ho CC, Bang E, Rejon CA, Libasci V, Pertchenko P, Hébert TE, Bernard DJ.

Endocrinology. 2014 May;155(5):1970-81. doi: 10.1210/en.2013-1741. Epub 2014 Mar 6.

PMID:
24601881
11.

Amino acid 72 of mouse and human GDF9 mature domain is responsible for altered homodimer bioactivities but has subtle effects on GDF9:BMP15 heterodimer activities.

Peng J, Wigglesworth K, Rangarajan A, Eppig JJ, Thompson TB, Matzuk MM.

Biol Reprod. 2014 Dec;91(6):142. doi: 10.1095/biolreprod.114.123158. Epub 2014 Sep 24.

12.

The crystal structure of the BMP-2:BMPR-IA complex and the generation of BMP-2 antagonists.

Nickel J, Dreyer MK, Kirsch T, Sebald W.

J Bone Joint Surg Am. 2001;83-A Suppl 1(Pt 1):S7-14. Review.

PMID:
11263668
13.

The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways.

Nohe A, Hassel S, Ehrlich M, Neubauer F, Sebald W, Henis YI, Knaus P.

J Biol Chem. 2002 Feb 15;277(7):5330-8. Epub 2001 Nov 19.

14.

Interaction between soluble type I receptor for bone morphogenetic protein and bone morphogenetic protein-4.

Natsume T, Tomita S, Iemura S, Kinto N, Yamaguchi A, Ueno N.

J Biol Chem. 1997 Apr 25;272(17):11535-40.

15.

Transforming growth factor (TGF-beta)-specific signaling by chimeric TGF-beta type II receptor with intracellular domain of activin type IIB receptor.

Persson U, Souchelnytskyi S, Franzén P, Miyazono K, ten Dijke P, Heldin CH.

J Biol Chem. 1997 Aug 22;272(34):21187-94.

16.

Gremlin1 preferentially binds to bone morphogenetic protein-2 (BMP-2) and BMP-4 over BMP-7.

Church RH, Krishnakumar A, Urbanek A, Geschwindner S, Meneely J, Bianchi A, Basta B, Monaghan S, Elliot C, Strömstedt M, Ferguson N, Martin F, Brazil DP.

Biochem J. 2015 Feb 15;466(1):55-68. doi: 10.1042/BJ20140771.

PMID:
25378054
17.

Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors.

Gilboa L, Nohe A, Geissendörfer T, Sebald W, Henis YI, Knaus P.

Mol Biol Cell. 2000 Mar;11(3):1023-35.

18.
19.

Localization of Smads, the TGF-beta family intracellular signaling components during endochondral ossification.

Sakou T, Onishi T, Yamamoto T, Nagamine T, Sampath Tk, Ten Dijke P.

J Bone Miner Res. 1999 Jul;14(7):1145-52.

20.

BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells.

Lavery K, Swain P, Falb D, Alaoui-Ismaili MH.

J Biol Chem. 2008 Jul 25;283(30):20948-58. doi: 10.1074/jbc.M800850200. Epub 2008 Apr 24.

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