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Items: 1 to 20 of 82

1.

Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity.

Schulz O, Pichlmair A, Rehwinkel J, Rogers NC, Scheuner D, Kato H, Takeuchi O, Akira S, Kaufman RJ, Reis e Sousa C.

Cell Host Microbe. 2010 May 20;7(5):354-61. doi: 10.1016/j.chom.2010.04.007.

2.

PKR Transduces MDA5-Dependent Signals for Type I IFN Induction.

Pham AM, Santa Maria FG, Lahiri T, Friedman E, Marié IJ, Levy DE.

PLoS Pathog. 2016 Mar 3;12(3):e1005489. doi: 10.1371/journal.ppat.1005489. eCollection 2016 Mar.

3.

Protein kinase PKR amplification of interferon β induction occurs through initiation factor eIF-2α-mediated translational control.

McAllister CS, Taghavi N, Samuel CE.

J Biol Chem. 2012 Oct 19;287(43):36384-92. doi: 10.1074/jbc.M112.390039. Epub 2012 Sep 4.

4.

PKR acts early in infection to suppress Semliki Forest virus production and strongly enhances the type I interferon response.

Barry G, Breakwell L, Fragkoudis R, Attarzadeh-Yazdi G, Rodriguez-Andres J, Kohl A, Fazakerley JK.

J Gen Virol. 2009 Jun;90(Pt 6):1382-91. doi: 10.1099/vir.0.007336-0. Epub 2009 Mar 4.

5.
7.

TRIM13 is a negative regulator of MDA5-mediated type I interferon production.

Narayan K, Waggoner L, Pham ST, Hendricks GL, Waggoner SN, Conlon J, Wang JP, Fitzgerald KA, Kang J.

J Virol. 2014 Sep;88(18):10748-57. doi: 10.1128/JVI.02593-13. Epub 2014 Jul 9.

9.

Alpha/beta interferon inhibits cap-dependent translation of viral but not cellular mRNA by a PKR-independent mechanism.

Tesfay MZ, Yin J, Gardner CL, Khoretonenko MV, Korneeva NL, Rhoads RE, Ryman KD, Klimstra WB.

J Virol. 2008 Mar;82(6):2620-30. Epub 2007 Dec 26.

10.

The RNA-activated protein kinase enhances the induction of interferon-beta and apoptosis mediated by cytoplasmic RNA sensors.

McAllister CS, Samuel CE.

J Biol Chem. 2009 Jan 16;284(3):1644-51. doi: 10.1074/jbc.M807888200. Epub 2008 Nov 20.

11.

Recombinant modified vaccinia virus Ankara generating excess early double-stranded RNA transiently activates protein kinase R and triggers enhanced innate immune responses.

Wolferstätter M, Schweneker M, Späth M, Lukassen S, Klingenberg M, Brinkmann K, Wielert U, Lauterbach H, Hochrein H, Chaplin P, Suter M, Hausmann J.

J Virol. 2014 Dec;88(24):14396-411. doi: 10.1128/JVI.02082-14. Epub 2014 Oct 8.

12.

Lloviu virus VP24 and VP35 proteins function as innate immune antagonists in human and bat cells.

Feagins AR, Basler CF.

Virology. 2015 Nov;485:145-52. doi: 10.1016/j.virol.2015.07.010. Epub 2015 Aug 6.

13.

Protein kinase regulated by dsRNA downregulates the interferon production in dengue virus- and dsRNA-stimulated human lung epithelial cells.

Li Y, Xie J, Wu S, Xia J, Zhang P, Liu C, Zhang P, Huang X.

PLoS One. 2013;8(1):e55108. doi: 10.1371/journal.pone.0055108. Epub 2013 Jan 25.

14.

Interferon β (IFN-β) Production during the Double-stranded RNA (dsRNA) Response in Hepatocytes Involves Coordinated and Feedforward Signaling through Toll-like Receptor 3 (TLR3), RNA-dependent Protein Kinase (PKR), Inducible Nitric Oxide Synthase (iNOS), and Src Protein.

Zhang L, Xiang W, Wang G, Yan Z, Zhu Z, Guo Z, Sengupta R, Chen AF, Loughran PA, Lu B, Wang Q, Billiar TR.

J Biol Chem. 2016 Jul 15;291(29):15093-107. doi: 10.1074/jbc.M116.717942. Epub 2016 May 17.

15.

Adenosine deaminase acting on RNA 1 (ADAR1) suppresses the induction of interferon by measles virus.

Li Z, Okonski KM, Samuel CE.

J Virol. 2012 Apr;86(7):3787-94. doi: 10.1128/JVI.06307-11. Epub 2012 Jan 25.

16.

Both RIG-I and MDA5 RNA helicases contribute to the induction of alpha/beta interferon in measles virus-infected human cells.

Ikegame S, Takeda M, Ohno S, Nakatsu Y, Nakanishi Y, Yanagi Y.

J Virol. 2010 Jan;84(1):372-9. doi: 10.1128/JVI.01690-09.

17.

Early alpha/beta interferon production by myeloid dendritic cells in response to UV-inactivated virus requires viral entry and interferon regulatory factor 3 but not MyD88.

Hidmark AS, McInerney GM, Nordström EK, Douagi I, Werner KM, Liljeström P, Karlsson Hedestam GB.

J Virol. 2005 Aug;79(16):10376-85.

18.

Characteristics of alpha/beta interferon induction after infection of murine fibroblasts with wild-type and mutant alphaviruses.

Burke CW, Gardner CL, Steffan JJ, Ryman KD, Klimstra WB.

Virology. 2009 Dec 5;395(1):121-32. doi: 10.1016/j.virol.2009.08.039. Epub 2009 Sep 25.

19.

Mouse embryonic stem cells are deficient in type I interferon expression in response to viral infections and double-stranded RNA.

Wang R, Wang J, Paul AM, Acharya D, Bai F, Huang F, Guo YL.

J Biol Chem. 2013 May 31;288(22):15926-36. doi: 10.1074/jbc.M112.421438. Epub 2013 Apr 11.

20.

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