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Items: 1 to 20 of 126

1.

Redundant function of cmaA2 and mmaA2 in Mycobacterium tuberculosis cis cyclopropanation of oxygenated mycolates.

Barkan D, Rao V, Sukenick GD, Glickman MS.

J Bacteriol. 2010 Jul;192(14):3661-8. doi: 10.1128/JB.00312-10. Epub 2010 May 14.

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The Mycobacterium tuberculosis cmaA2 gene encodes a mycolic acid trans-cyclopropane synthetase.

Glickman MS, Cahill SM, Jacobs WR Jr.

J Biol Chem. 2001 Jan 19;276(3):2228-33. Epub 2000 Nov 22.

5.

Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria.

Alahari A, Trivelli X, Guérardel Y, Dover LG, Besra GS, Sacchettini JC, Reynolds RC, Coxon GD, Kremer L.

PLoS One. 2007 Dec 19;2(12):e1343.

6.

Mycobacterium tuberculosis lacking all mycolic acid cyclopropanation is viable but highly attenuated and hyperinflammatory in mice.

Barkan D, Hedhli D, Yan HG, Huygen K, Glickman MS.

Infect Immun. 2012 Jun;80(6):1958-68. doi: 10.1128/IAI.00021-12. Epub 2012 Mar 19.

7.

Temperature-dependent regulation of mycolic acid cyclopropanation in saprophytic mycobacteria: role of the Mycobacterium smegmatis 1351 gene (MSMEG_1351) in CIS-cyclopropanation of alpha-mycolates.

Alibaud L, Alahari A, Trivelli X, Ojha AK, Hatfull GF, Guerardel Y, Kremer L.

J Biol Chem. 2010 Jul 9;285(28):21698-707. doi: 10.1074/jbc.M110.125724. Epub 2010 May 10.

8.

MMAS-1, the branch point between cis- and trans-cyclopropane-containing oxygenated mycolates in Mycobacterium tuberculosis.

Yuan Y, Crane DC, Musser JM, Sreevatsan S, Barry CE 3rd.

J Biol Chem. 1997 Apr 11;272(15):10041-9.

9.

Tracking the putative biosynthetic precursors of oxygenated mycolates of Mycobacterium tuberculosis. Structural analysis of fatty acids of a mutant strain deviod of methoxy- and ketomycolates.

Dinadayala P, Laval F, Raynaud C, Lemassu A, Laneelle MA, Laneelle G, Daffe M.

J Biol Chem. 2003 Feb 28;278(9):7310-9. Epub 2002 Dec 6.

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Separation and characterization of individual mycolic acids in representative mycobacteria.

Watanabe M, Aoyagi Y, Ridell M, Minnikin DE.

Microbiology. 2001 Jul;147(Pt 7):1825-37.

PMID:
11429460
12.

Identification of a gene involved in the biosynthesis of cyclopropanated mycolic acids in Mycobacterium tuberculosis.

Yuan Y, Lee RE, Besra GS, Belisle JT, Barry CE 3rd.

Proc Natl Acad Sci U S A. 1995 Jul 3;92(14):6630-4.

13.

Mycolic acid cyclopropanation is essential for viability, drug resistance, and cell wall integrity of Mycobacterium tuberculosis.

Barkan D, Liu Z, Sacchettini JC, Glickman MS.

Chem Biol. 2009 May 29;16(5):499-509. doi: 10.1016/j.chembiol.2009.04.001.

14.

Investigating the function of the putative mycolic acid methyltransferase UmaA: divergence between the Mycobacterium smegmatis and Mycobacterium tuberculosis proteins.

Laval F, Haites R, Movahedzadeh F, Lemassu A, Wong CY, Stoker N, Billman-Jacobe H, Daffé M.

J Biol Chem. 2008 Jan 18;283(3):1419-27. Epub 2007 Nov 15.

15.

Phosphorylation of mycobacterial PcaA inhibits mycolic acid cyclopropanation: consequences for intracellular survival and for phagosome maturation block.

Corrales RM, Molle V, Leiba J, Mourey L, de Chastellier C, Kremer L.

J Biol Chem. 2012 Jul 27;287(31):26187-99. doi: 10.1074/jbc.M112.373209. Epub 2012 May 23.

16.

Mycolic acid methyltransferase, MmaA4, is necessary for thiacetazone susceptibility in Mycobacterium tuberculosis.

Alahari A, Alibaud L, Trivelli X, Gupta R, Lamichhane G, Reynolds RC, Bishai WR, Guerardel Y, Kremer L.

Mol Microbiol. 2009 Mar;71(5):1263-77. doi: 10.1111/j.1365-2958.2009.06604.x. Epub 2009 Jan 15.

17.

Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis.

Huang CC, Smith CV, Glickman MS, Jacobs WR Jr, Sacchettini JC.

J Biol Chem. 2002 Mar 29;277(13):11559-69. Epub 2001 Dec 26.

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Molecular dynamics investigation of the active site dynamics of mycobacterial cyclopropane synthase during various stages of the cyclopropanation process.

Choudhury C, Deva Priyakumar U, Sastry GN.

J Struct Biol. 2014 Jul;187(1):38-48. doi: 10.1016/j.jsb.2014.04.007. Epub 2014 Apr 26.

PMID:
24780591
20.

Evolution of Mycolic Acid Biosynthesis Genes and Their Regulation during Starvation in Mycobacterium tuberculosis.

Jamet S, Quentin Y, Coudray C, Texier P, Laval F, Daffé M, Fichant G, Cam K.

J Bacteriol. 2015 Dec;197(24):3797-811. doi: 10.1128/JB.00433-15. Epub 2015 Sep 28.

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