Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 154

1.

S-nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegeneration.

Nakamura T, Cieplak P, Cho DH, Godzik A, Lipton SA.

Mitochondrion. 2010 Aug;10(5):573-8. doi: 10.1016/j.mito.2010.04.007. Epub 2010 May 4. Review.

2.

S-nitrosylation of dynamin-related protein 1 mediates mutant huntingtin-induced mitochondrial fragmentation and neuronal injury in Huntington's disease.

Haun F, Nakamura T, Shiu AD, Cho DH, Tsunemi T, Holland EA, La Spada AR, Lipton SA.

Antioxid Redox Signal. 2013 Oct 10;19(11):1173-84. doi: 10.1089/ars.2012.4928. Epub 2013 Jun 20.

3.

Nitric oxide links mitochondrial fission to Alzheimer's disease.

Westermann B.

Sci Signal. 2009 May 5;2(69):pe29. doi: 10.1126/scisignal.269pe29.

PMID:
19417214
4.

S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury.

Cho DH, Nakamura T, Fang J, Cieplak P, Godzik A, Gu Z, Lipton SA.

Science. 2009 Apr 3;324(5923):102-5. doi: 10.1126/science.1171091.

5.

S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease.

Bossy B, Petrilli A, Klinglmayr E, Chen J, Lütz-Meindl U, Knott AB, Masliah E, Schwarzenbacher R, Bossy-Wetzel E.

J Alzheimers Dis. 2010;20 Suppl 2:S513-26. doi: 10.3233/JAD-2010-100552.

7.
8.
9.

Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases.

Reddy PH, Reddy TP, Manczak M, Calkins MJ, Shirendeb U, Mao P.

Brain Res Rev. 2011 Jun 24;67(1-2):103-18. doi: 10.1016/j.brainresrev.2010.11.004. Epub 2010 Dec 8. Review.

10.

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.

Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X.

J Neurosci. 2009 Jul 15;29(28):9090-103. doi: 10.1523/JNEUROSCI.1357-09.2009.

11.

Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell.

Gan X, Huang S, Wu L, Wang Y, Hu G, Li G, Zhang H, Yu H, Swerdlow RH, Chen JX, Yan SS.

Biochim Biophys Acta. 2014 Feb;1842(2):220-31. doi: 10.1016/j.bbadis.2013.11.009. Epub 2013 Nov 16.

12.

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity.

Song W, Chen J, Petrilli A, Liot G, Klinglmayr E, Zhou Y, Poquiz P, Tjong J, Pouladi MA, Hayden MR, Masliah E, Ellisman M, Rouiller I, Schwarzenbacher R, Bossy B, Perkins G, Bossy-Wetzel E.

Nat Med. 2011 Mar;17(3):377-82. doi: 10.1038/nm.2313. Epub 2011 Feb 20.

13.

Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation.

Akhtar MW, Sanz-Blasco S, Dolatabadi N, Parker J, Chon K, Lee MS, Soussou W, McKercher SR, Ambasudhan R, Nakamura T, Lipton SA.

Nat Commun. 2016 Jan 8;7:10242. doi: 10.1038/ncomms10242.

14.

S-nitrosylation of critical protein thiols mediates protein misfolding and mitochondrial dysfunction in neurodegenerative diseases.

Nakamura T, Lipton SA.

Antioxid Redox Signal. 2011 Apr 15;14(8):1479-92. doi: 10.1089/ars.2010.3570. Epub 2011 Jan 8. Review.

15.

Mitochondrial dynamics in neurodegeneration.

Itoh K, Nakamura K, Iijima M, Sesaki H.

Trends Cell Biol. 2013 Feb;23(2):64-71. doi: 10.1016/j.tcb.2012.10.006. Epub 2012 Nov 16. Review.

16.

Increased mitochondrial fission and neuronal dysfunction in Huntington's disease: implications for molecular inhibitors of excessive mitochondrial fission.

Reddy PH.

Drug Discov Today. 2014 Jul;19(7):951-5. doi: 10.1016/j.drudis.2014.03.020. Epub 2014 Mar 28. Review.

17.

Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.

Shirendeb UP, Calkins MJ, Manczak M, Anekonda V, Dufour B, McBride JL, Mao P, Reddy PH.

Hum Mol Genet. 2012 Jan 15;21(2):406-20. doi: 10.1093/hmg/ddr475. Epub 2011 Oct 13.

18.

Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons.

Uo T, Dworzak J, Kinoshita C, Inman DM, Kinoshita Y, Horner PJ, Morrison RS.

Exp Neurol. 2009 Aug;218(2):274-85. doi: 10.1016/j.expneurol.2009.05.010. Epub 2009 May 13.

19.

Tau promotes neurodegeneration via DRP1 mislocalization in vivo.

DuBoff B, Götz J, Feany MB.

Neuron. 2012 Aug 23;75(4):618-32. doi: 10.1016/j.neuron.2012.06.026.

20.

Mitochondrial dynamics in cell death and neurodegeneration.

Cho DH, Nakamura T, Lipton SA.

Cell Mol Life Sci. 2010 Oct;67(20):3435-47. doi: 10.1007/s00018-010-0435-2. Epub 2010 Jun 25. Review.

PMID:
20577776

Supplemental Content

Support Center