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Items: 1 to 20 of 109

1.

Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4.

Qi S, Pang Y, Hu Q, Liu Q, Li H, Zhou Y, He T, Liang Q, Liu Y, Yuan X, Luo G, Li H, Wang J, Yan N, Shi Y.

Cell. 2010 Apr 30;141(3):446-57. doi: 10.1016/j.cell.2010.03.017.

2.

Mechanistic insights into CED-4-mediated activation of CED-3.

Huang W, Jiang T, Choi W, Qi S, Pang Y, Hu Q, Xu Y, Gong X, Jeffrey PD, Wang J, Shi Y.

Genes Dev. 2013 Sep 15;27(18):2039-48. doi: 10.1101/gad.224428.113.

3.

Apoptosome assembly.

Shi Y.

Methods Enzymol. 2008;442:141-56. doi: 10.1016/S0076-6879(08)01407-9.

PMID:
18662568
4.

Apoptosome structure, assembly, and procaspase activation.

Yuan S, Akey CW.

Structure. 2013 Apr 2;21(4):501-15. doi: 10.1016/j.str.2013.02.024. Review.

5.

Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans.

Yan N, Chai J, Lee ES, Gu L, Liu Q, He J, Wu JW, Kokel D, Li H, Hao Q, Xue D, Shi Y.

Nature. 2005 Oct 6;437(7060):831-7.

PMID:
16208361
6.

Cap-independent translation promotes C. elegans germ cell apoptosis through Apaf-1/CED-4 in a caspase-dependent mechanism.

Contreras V, Friday AJ, Morrison JK, Hao E, Keiper BD.

PLoS One. 2011;6(9):e24444. doi: 10.1371/journal.pone.0024444. Epub 2011 Sep 1.

7.

2:1 Stoichiometry of the CED-4-CED-9 complex and the tetrameric CED-4: insights into the regulation of CED-3 activation.

Yan N, Xu Y, Shi Y.

Cell Cycle. 2006 Jan;5(1):31-4. Epub 2006 Jan 18. Review.

PMID:
16294007
8.

Inhibition of CED-3 zymogen activation and apoptosis in Caenorhabditis elegans by caspase homolog CSP-3.

Geng X, Shi Y, Nakagawa A, Yoshina S, Mitani S, Shi Y, Xue D.

Nat Struct Mol Biol. 2008 Oct;15(10):1094-101. doi: 10.1038/nsmb.1488. Epub 2008 Sep 7.

9.

Direct physical interaction between the Caenorhabditis elegans 'death proteins' CED-3 and CED-4.

Irmler M, Hofmann K, Vaux D, Tschopp J.

FEBS Lett. 1997 Apr 7;406(1-2):189-90.

10.

Apoptosome: a platform for the activation of initiator caspases.

Bao Q, Shi Y.

Cell Death Differ. 2007 Jan;14(1):56-65. Epub 2006 Sep 15. Review.

11.

Mechanical aspects of apoptosome assembly.

Shi Y.

Curr Opin Cell Biol. 2006 Dec;18(6):677-84. Epub 2006 Oct 12. Review.

PMID:
17046227
12.

Apoptosomes: engines for caspase activation.

Adams JM, Cory S.

Curr Opin Cell Biol. 2002 Dec;14(6):715-20. Review.

PMID:
12473344
13.

C. elegans MAC-1, an essential member of the AAA family of ATPases, can bind CED-4 and prevent cell death.

Wu D, Chen PJ, Chen S, Hu Y, Nuñez G, Ellis RE.

Development. 1999 May;126(9):2021-31.

14.

Caenorhabditis elegans caspase homolog CSP-2 inhibits CED-3 autoactivation and apoptosis in germ cells.

Geng X, Zhou QH, Kage-Nakadai E, Shi Y, Yan N, Mitani S, Xue D.

Cell Death Differ. 2009 Oct;16(10):1385-94. doi: 10.1038/cdd.2009.88. Epub 2009 Jul 3.

15.

Crystal structure of the cell corpse engulfment protein CED-2 in Caenorhabditis elegans.

Kang Y, Xu J, Liu Y, Sun J, Sun D, Hu Y, Liu Y.

Biochem Biophys Res Commun. 2011 Jul 1;410(2):189-94. doi: 10.1016/j.bbrc.2011.05.051. Epub 2011 May 17.

PMID:
21616056
16.

ATP-activated oligomerization as a mechanism for apoptosis regulation: fold and mechanism prediction for CED-4.

Jaroszewski L, Rychlewski L, Reed JC, Godzik A.

Proteins. 2000 May 15;39(3):197-203.

PMID:
10737940
17.

Structure of the apoptosome: mechanistic insights into activation of an initiator caspase from Drosophila.

Pang Y, Bai XC, Yan C, Hao Q, Chen Z, Wang JW, Scheres SH, Shi Y.

Genes Dev. 2015 Feb 1;29(3):277-87. doi: 10.1101/gad.255877.114.

18.

Disruption of the CED-9.CED-4 complex by EGL-1 is a critical step for programmed cell death in Caenorhabditis elegans.

del Peso L, Gonzalez VM, Inohara N, Ellis RE, Núñez G.

J Biol Chem. 2000 Sep 1;275(35):27205-11.

19.

The nematode death machine in 3D.

Pop C, Salvesen GS.

Cell. 2005 Oct 21;123(2):192-3.

20.

Apoptosis: calling time on apoptosome activity.

Adrain C, Martin SJ.

Sci Signal. 2009 Oct 6;2(91):pe62. doi: 10.1126/scisignal.291pe62.

PMID:
19809088

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