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Items: 1 to 20 of 162


A mutation in the cytosolic O-acetylserine (thiol) lyase induces a genome-dependent early leaf death phenotype in Arabidopsis.

Shirzadian-Khorramabad R, Jing HC, Everts GE, Schippers JH, Hille J, Dijkwel PP.

BMC Plant Biol. 2010 Apr 29;10:80. doi: 10.1186/1471-2229-10-80.


Enzymes of cysteine synthesis show extensive and conserved modifications patterns that include N(α)-terminal acetylation.

Wirtz M, Heeg C, Samami AA, Ruppert T, Hell R.

Amino Acids. 2010 Oct;39(4):1077-86. doi: 10.1007/s00726-010-0694-0. Epub 2010 Jul 24.


Analysis of the Arabidopsis O-acetylserine(thiol)lyase gene family demonstrates compartment-specific differences in the regulation of cysteine synthesis.

Heeg C, Kruse C, Jost R, Gutensohn M, Ruppert T, Wirtz M, Hell R.

Plant Cell. 2008 Jan;20(1):168-85. doi: 10.1105/tpc.107.056747. Epub 2008 Jan 25.


Activation of R-mediated innate immunity and disease susceptibility is affected by mutations in a cytosolic O-acetylserine (thiol) lyase in Arabidopsis.

Tahir J, Watanabe M, Jing HC, Hunter DA, Tohge T, Nunes-Nesi A, Brotman Y, Fernie AR, Hoefgen R, Dijkwel PP.

Plant J. 2013 Jan;73(1):118-30. doi: 10.1111/tpj.12021. Epub 2012 Nov 5.


Successful fertilization requires the presence of at least one major O-acetylserine(thiol)lyase for cysteine synthesis in pollen of Arabidopsis.

Birke H, Heeg C, Wirtz M, Hell R.

Plant Physiol. 2013 Oct;163(2):959-72. doi: 10.1104/pp.113.221200. Epub 2013 Sep 3.


The role of compartment-specific cysteine synthesis for sulfur homeostasis during H2S exposure in Arabidopsis.

Birke H, De Kok LJ, Wirtz M, Hell R.

Plant Cell Physiol. 2015 Feb;56(2):358-67. doi: 10.1093/pcp/pcu166. Epub 2014 Nov 20.


Mitochondrial cysteine synthase complex regulates O-acetylserine biosynthesis in plants.

Wirtz M, Beard KF, Lee CP, Boltz A, Schwarzländer M, Fuchs C, Meyer AJ, Heeg C, Sweetlove LJ, Ratcliffe RG, Hell R.

J Biol Chem. 2012 Aug 10;287(33):27941-7. doi: 10.1074/jbc.M112.372656. Epub 2012 Jun 22.


Analysis of cytosolic and plastidic serine acetyltransferase mutants and subcellular metabolite distributions suggests interplay of the cellular compartments for cysteine biosynthesis in Arabidopsis.

Krueger S, Niehl A, Lopez Martin MC, Steinhauser D, Donath A, Hildebrandt T, Romero LC, Hoefgen R, Gotor C, Hesse H.

Plant Cell Environ. 2009 Apr;32(4):349-67. doi: 10.1111/j.1365-3040.2008.01928.x.


Impact of sulfur starvation on cysteine biosynthesis in T-DNA mutants deficient for compartment-specific serine-acetyltransferase.

Krueger S, Donath A, Lopez-Martin MC, Hoefgen R, Gotor C, Hesse H.

Amino Acids. 2010 Oct;39(4):1029-42. doi: 10.1007/s00726-010-0580-9. Epub 2010 Apr 9.


O-acetylserine (thiol) lyase: an enigmatic enzyme of plant cysteine biosynthesis revisited in Arabidopsis thaliana.

Wirtz M, Droux M, Hell R.

J Exp Bot. 2004 Aug;55(404):1785-98. Epub 2004 Jul 16.


Allosterically gated enzyme dynamics in the cysteine synthase complex regulate cysteine biosynthesis in Arabidopsis thaliana.

Feldman-Salit A, Wirtz M, Lenherr ED, Throm C, Hothorn M, Scheffzek K, Hell R, Wade RC.

Structure. 2012 Feb 8;20(2):292-302. doi: 10.1016/j.str.2011.11.019.


Mitochondrial serine acetyltransferase functions as a pacemaker of cysteine synthesis in plant cells.

Haas FH, Heeg C, Queiroz R, Bauer A, Wirtz M, Hell R.

Plant Physiol. 2008 Oct;148(2):1055-67. doi: 10.1104/pp.108.125237. Epub 2008 Aug 27.


An O-acetylserine(thiol)lyase homolog with L-cysteine desulfhydrase activity regulates cysteine homeostasis in Arabidopsis.

Alvarez C, Calo L, Romero LC, García I, Gotor C.

Plant Physiol. 2010 Feb;152(2):656-69. doi: 10.1104/pp.109.147975. Epub 2009 Dec 2.


Biochemical properties of nematode O-acetylserine(thiol)lyase paralogs imply their distinct roles in hydrogen sulfide homeostasis.

Vozdek R, Hnízda A, Krijt J, Será L, Kožich V.

Biochim Biophys Acta. 2013 Dec;1834(12):2691-701. doi: 10.1016/j.bbapap.2013.09.020. Epub 2013 Oct 4.


Functional analysis of the cysteine synthase protein complex from plants: structural, biochemical and regulatory properties.

Wirtz M, Hell R.

J Plant Physiol. 2006 Feb;163(3):273-86. Epub 2005 Dec 28. Review.


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