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Items: 1 to 20 of 143


Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response.

Salton M, Lerenthal Y, Wang SY, Chen DJ, Shiloh Y.

Cell Cycle. 2010 Apr 15;9(8):1568-76. Epub 2010 Apr 15.


Characterization of DNA binding and pairing activities associated with the native SFPQ·NONO DNA repair protein complex.

Udayakumar D, Dynan WS.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):473-8. doi: 10.1016/j.bbrc.2015.05.024. Epub 2015 May 18.


Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks.

Levy-Barda A, Lerenthal Y, Davis AJ, Chung YM, Essers J, Shao Z, van Vliet N, Chen DJ, Hu MC, Kanaar R, Ziv Y, Shiloh Y.

Cell Cycle. 2011 Dec 15;10(24):4300-10. doi: 10.4161/cc.10.24.18642. Epub 2011 Dec 15.


PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks.

Krietsch J, Caron MC, Gagné JP, Ethier C, Vignard J, Vincent M, Rouleau M, Hendzel MJ, Poirier GG, Masson JY.

Nucleic Acids Res. 2012 Nov 1;40(20):10287-301. doi: 10.1093/nar/gks798. Epub 2012 Aug 31.


Sequences in PSF/SFPQ mediate radioresistance and recruitment of PSF/SFPQ-containing complexes to DNA damage sites in human cells.

Ha K, Takeda Y, Dynan WS.

DNA Repair (Amst). 2011 Mar 7;10(3):252-9. doi: 10.1016/j.dnarep.2010.11.009. Epub 2010 Dec 8.


The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax.

Goodarzi AA, Jeggo P, Lobrich M.

DNA Repair (Amst). 2010 Dec 10;9(12):1273-82. doi: 10.1016/j.dnarep.2010.09.013. Epub 2010 Oct 30. Review.


Arginine methylation and citrullination of splicing factor proline- and glutamine-rich (SFPQ/PSF) regulates its association with mRNA.

Snijders AP, Hautbergue GM, Bloom A, Williamson JC, Minshull TC, Phillips HL, Mihaylov SR, Gjerde DT, Hornby DP, Wilson SA, Hurd PJ, Dickman MJ.

RNA. 2015 Mar;21(3):347-59. doi: 10.1261/rna.045138.114. Epub 2015 Jan 20.


ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair.

Segal-Raz H, Mass G, Baranes-Bachar K, Lerenthal Y, Wang SY, Chung YM, Ziv-Lehrman S, Ström CE, Helleday T, Hu MC, Chen DJ, Shiloh Y.

EMBO Rep. 2011 Jul 1;12(7):713-9. doi: 10.1038/embor.2011.96.


Proteomic identification of PSF and p54(nrb) as TopBP1-interacting proteins.

Kuhnert A, Schmidt U, Monajembashi S, Franke C, Schlott B, Grosse F, Greulich KO, Saluz HP, Hänel F.

J Cell Biochem. 2012 May;113(5):1744-53. doi: 10.1002/jcb.24045.


Involvement of p54(nrb), a PSF partner protein, in DNA double-strand break repair and radioresistance.

Li S, Kuhne WW, Kulharya A, Hudson FZ, Ha K, Cao Z, Dynan WS.

Nucleic Acids Res. 2009 Nov;37(20):6746-53. doi: 10.1093/nar/gkp741. Epub 2009 Sep 16.


Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.

Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, Wang SY, Eppink B, Chung YM, Shalev G, Shema E, Shkedy D, Smorodinsky NI, van Vliet N, Kuster B, Mann M, Ciechanover A, Dahm-Daphi J, Kanaar R, Hu MC, Chen DJ, Oren M, Shiloh Y.

Mol Cell. 2011 Mar 4;41(5):529-42. doi: 10.1016/j.molcel.2011.02.015.


Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double strand breaks.

Tomimatsu N, Tahimic CG, Otsuki A, Burma S, Fukuhara A, Sato K, Shiota G, Oshimura M, Chen DJ, Kurimasa A.

J Biol Chem. 2007 Apr 6;282(14):10138-45. Epub 2007 Feb 1.


MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks.

Fraser M, Harding SM, Zhao H, Coackley C, Durocher D, Bristow RG.

Cell Cycle. 2011 Jul 1;10(13):2218-32. Epub 2011 Jul 1.


NBN phosphorylation regulates the accumulation of MRN and ATM at sites of DNA double-strand breaks.

Wen J, Cerosaletti K, Schultz KJ, Wright JA, Concannon P.

Oncogene. 2013 Sep 12;32(37):4448-56. doi: 10.1038/onc.2012.443. Epub 2012 Nov 12.


NONO regulates the intra-S-phase checkpoint in response to UV radiation.

Alfano L, Costa C, Caporaso A, Altieri A, Indovina P, Macaluso M, Giordano A, Pentimalli F.

Oncogene. 2016 Feb 4;35(5):567-76. doi: 10.1038/onc.2015.107. Epub 2015 Apr 20.


MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair.

Sharma GG, So S, Gupta A, Kumar R, Cayrou C, Avvakumov N, Bhadra U, Pandita RK, Porteus MH, Chen DJ, Cote J, Pandita TK.

Mol Cell Biol. 2010 Jul;30(14):3582-95. doi: 10.1128/MCB.01476-09. Epub 2010 May 17.


DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks.

Yu Y, Mahaney BL, Yano K, Ye R, Fang S, Douglas P, Chen DJ, Lees-Miller SP.

DNA Repair (Amst). 2008 Oct 1;7(10):1680-92. doi: 10.1016/j.dnarep.2008.06.015. Epub 2008 Aug 3.


Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation.

Xue L, Yu D, Furusawa Y, Okayasu R, Tong J, Cao J, Fan S.

Mutat Res. 2009 Nov 2;670(1-2):15-23. doi: 10.1016/j.mrfmmm.2009.06.016. Epub 2009 Jul 5.


Double-strand break repair deficiency in NONO knockout murine embryonic fibroblasts and compensation by spontaneous upregulation of the PSPC1 paralog.

Li S, Li Z, Shu FJ, Xiong H, Phillips AC, Dynan WS.

Nucleic Acids Res. 2014 Sep;42(15):9771-80. doi: 10.1093/nar/gku650. Epub 2014 Aug 6.


Chk1 inhibition after replicative stress activates a double strand break response mediated by ATM and DNA-dependent protein kinase.

McNeely S, Conti C, Sheikh T, Patel H, Zabludoff S, Pommier Y, Schwartz G, Tse A.

Cell Cycle. 2010 Mar 1;9(5):995-1004. Epub 2010 Mar 14.


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