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Items: 1 to 20 of 68

1.

Epigenetics, the epicenter of the hypoxic response.

Watson JA, Watson CJ, McCann A, Baugh J.

Epigenetics. 2010 May 16;5(4):293-6. Epub 2010 May 3. Review.

PMID:
20418669
3.

Activating transcription factor 2 increases transactivation and protein stability of hypoxia-inducible factor 1alpha in hepatocytes.

Choi JH, Cho HK, Choi YH, Cheong J.

Biochem J. 2009 Nov 11;424(2):285-96. doi: 10.1042/BJ20090371.

PMID:
19712049
4.

Differential hypoxic regulation of hypoxia-inducible factors 1alpha and 2alpha.

Lin Q, Cong X, Yun Z.

Mol Cancer Res. 2011 Jun;9(6):757-65. doi: 10.1158/1541-7786.MCR-11-0053. Epub 2011 May 13.

5.
6.

Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90.

Trisciuoglio D, Gabellini C, Desideri M, Ziparo E, Zupi G, Del Bufalo D.

PLoS One. 2010 Jul 27;5(7):e11772. doi: 10.1371/journal.pone.0011772.

7.

Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth.

Krieg AJ, Rankin EB, Chan D, Razorenova O, Fernandez S, Giaccia AJ.

Mol Cell Biol. 2010 Jan;30(1):344-53. doi: 10.1128/MCB.00444-09.

8.

Regulation of the HIF-system in human macrophages--differential regulation of HIF-α subunits under sustained hypoxia.

Poitz DM, Augstein A, Hesse K, Christoph M, Ibrahim K, Braun-Dullaeus RC, Strasser RH, Schmeißer A.

Mol Immunol. 2014 Feb;57(2):226-35. doi: 10.1016/j.molimm.2013.10.001. Epub 2013 Oct 29.

PMID:
24176785
9.

Functional and transcriptional induction of aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1α.

Abreu-Rodríguez I, Sánchez Silva R, Martins AP, Soveral G, Toledo-Aral JJ, López-Barneo J, Echevarría M.

PLoS One. 2011;6(12):e28385. doi: 10.1371/journal.pone.0028385. Epub 2011 Dec 7.

10.

The insulin-PI3K/TOR pathway induces a HIF-dependent transcriptional response in Drosophila by promoting nuclear localization of HIF-alpha/Sima.

Dekanty A, Lavista-Llanos S, Irisarri M, Oldham S, Wappner P.

J Cell Sci. 2005 Dec 1;118(Pt 23):5431-41. Epub 2005 Nov 8.

11.

Stabilization of hypoxia-inducible factor-1alpha protein in hypoxia occurs independently of mitochondrial reactive oxygen species production.

Chua YL, Dufour E, Dassa EP, Rustin P, Jacobs HT, Taylor CT, Hagen T.

J Biol Chem. 2010 Oct 8;285(41):31277-84. doi: 10.1074/jbc.M110.158485. Epub 2010 Jul 30.

12.

Regulation of HIF-1alpha at the transcriptional level.

Görlach A.

Curr Pharm Des. 2009;15(33):3844-52. Review.

PMID:
19671046
14.

[HIF-1 activation during tumor progression: implications and consequences].

Lauzier MC, Michaud MD, Déry MA, Richard DE.

Bull Cancer. 2006 Apr;93(4):349-56. Review. French.

15.

Hypoxia induces genomic DNA demethylation through the activation of HIF-1α and transcriptional upregulation of MAT2A in hepatoma cells.

Liu Q, Liu L, Zhao Y, Zhang J, Wang D, Chen J, He Y, Wu J, Zhang Z, Liu Z.

Mol Cancer Ther. 2011 Jun;10(6):1113-23. doi: 10.1158/1535-7163.MCT-10-1010. Epub 2011 Apr 1.

16.

HIF-1α-induced histone demethylase JMJD2B contributes to the malignant phenotype of colorectal cancer cells via an epigenetic mechanism.

Fu L, Chen L, Yang J, Ye T, Chen Y, Fang J.

Carcinogenesis. 2012 Sep;33(9):1664-73. doi: 10.1093/carcin/bgs217. Epub 2012 Jun 27.

PMID:
22745382
17.

Effect of hypoxia-inducible factor-1alpha on transcription of survivin in non-small cell lung cancer.

Chen YQ, Zhao CL, Li W.

J Exp Clin Cancer Res. 2009 Feb 26;28:29. doi: 10.1186/1756-9966-28-29.

18.

A Key role for cyclic AMP-responsive element binding protein in hypoxia-mediated activation of the angiogenesis factor CCN1 (CYR61) in Tumor cells.

Meyuhas R, Pikarsky E, Tavor E, Klar A, Abramovitch R, Hochman J, Lago TG, Honigman A.

Mol Cancer Res. 2008 Sep;6(9):1397-409. doi: 10.1158/1541-7786.MCR-07-2086.

19.

Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis.

Xia X, Lemieux ME, Li W, Carroll JS, Brown M, Liu XS, Kung AL.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4260-5. doi: 10.1073/pnas.0810067106. Epub 2009 Mar 2.

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