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Items: 1 to 20 of 103

1.

Human cytomegalovirus UL141 promotes efficient downregulation of the natural killer cell activating ligand CD112.

Prod'homme V, Sugrue DM, Stanton RJ, Nomoto A, Davies J, Rickards CR, Cochrane D, Moore M, Wilkinson GW, Tomasec P.

J Gen Virol. 2010 Aug;91(Pt 8):2034-9. doi: 10.1099/vir.0.021931-0. Epub 2010 Apr 21.

2.

Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141.

Tomasec P, Wang EC, Davison AJ, Vojtesek B, Armstrong M, Griffin C, McSharry BP, Morris RJ, Llewellyn-Lacey S, Rickards C, Nomoto A, Sinzger C, Wilkinson GW.

Nat Immunol. 2005 Feb;6(2):181-8. Epub 2005 Jan 9.

3.

The structure of cytomegalovirus immune modulator UL141 highlights structural Ig-fold versatility for receptor binding.

Nemčovičová I, Zajonc DM.

Acta Crystallogr D Biol Crystallogr. 2014 Mar;70(Pt 3):851-62. doi: 10.1107/S1399004713033750. Epub 2014 Feb 22.

4.

Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112).

Tahara-Hanaoka S, Shibuya K, Onoda Y, Zhang H, Yamazaki S, Miyamoto A, Honda S, Lanier LL, Shibuya A.

Int Immunol. 2004 Apr;16(4):533-8.

PMID:
15039383
5.

Distinct Roles for Human Cytomegalovirus Immediate Early Proteins IE1 and IE2 in the Transcriptional Regulation of MICA and PVR/CD155 Expression.

Pignoloni B, Fionda C, Dell'Oste V, Luganini A, Cippitelli M, Zingoni A, Landolfo S, Gribaudo G, Santoni A, Cerboni C.

J Immunol. 2016 Nov 15;197(10):4066-4078. Epub 2016 Oct 12.

6.

Modulation of natural killer cells by human cytomegalovirus.

Wilkinson GW, Tomasec P, Stanton RJ, Armstrong M, Prod'homme V, Aicheler R, McSharry BP, Rickards CR, Cochrane D, Llewellyn-Lacey S, Wang EC, Griffin CA, Davison AJ.

J Clin Virol. 2008 Mar;41(3):206-12. Review.

7.

Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction.

Pende D, Castriconi R, Romagnani P, Spaggiari GM, Marcenaro S, Dondero A, Lazzeri E, Lasagni L, Martini S, Rivera P, Capobianco A, Moretta L, Moretta A, Bottino C.

Blood. 2006 Mar 1;107(5):2030-6. Epub 2005 Nov 22.

8.

Plasma membrane profiling defines an expanded class of cell surface proteins selectively targeted for degradation by HCMV US2 in cooperation with UL141.

Hsu JL, van den Boomen DJ, Tomasec P, Weekes MP, Antrobus R, Stanton RJ, Ruckova E, Sugrue D, Wilkie GS, Davison AJ, Wilkinson GW, Lehner PJ.

PLoS Pathog. 2015 Apr 14;11(4):e1004811. doi: 10.1371/journal.ppat.1004811. eCollection 2015 Apr.

9.

Human cytomegalovirus glycoprotein UL141 targets the TRAIL death receptors to thwart host innate antiviral defenses.

Smith W, Tomasec P, Aicheler R, Loewendorf A, Nemčovičová I, Wang EC, Stanton RJ, Macauley M, Norris P, Willen L, Ruckova E, Nomoto A, Schneider P, Hahn G, Zajonc DM, Ware CF, Wilkinson GW, Benedict CA.

Cell Host Microbe. 2013 Mar 13;13(3):324-35. doi: 10.1016/j.chom.2013.02.003.

10.

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule.

Bottino C, Castriconi R, Pende D, Rivera P, Nanni M, Carnemolla B, Cantoni C, Grassi J, Marcenaro S, Reymond N, Vitale M, Moretta L, Lopez M, Moretta A.

J Exp Med. 2003 Aug 18;198(4):557-67. Epub 2003 Aug 11.

11.

Structure of human cytomegalovirus UL141 binding to TRAIL-R2 reveals novel, non-canonical death receptor interactions.

Nemčovičová I, Benedict CA, Zajonc DM.

PLoS Pathog. 2013 Mar;9(3):e1003224. doi: 10.1371/journal.ppat.1003224. Epub 2013 Mar 21.

12.

Effects of human cytomegalovirus infection on ligands for the activating NKG2D receptor of NK cells: up-regulation of UL16-binding protein (ULBP)1 and ULBP2 is counteracted by the viral UL16 protein.

Rölle A, Mousavi-Jazi M, Eriksson M, Odeberg J, Söderberg-Nauclér C, Cosman D, Kärre K, Cerboni C.

J Immunol. 2003 Jul 15;171(2):902-8.

13.

Increased CD112 expression in methylcholanthrene-induced tumors in CD155-deficient mice.

Nagumo Y, Iguchi-Manaka A, Yamashita-Kanemaru Y, Abe F, Bernhardt G, Shibuya A, Shibuya K.

PLoS One. 2014 Nov 10;9(11):e112415. doi: 10.1371/journal.pone.0112415. eCollection 2014.

14.

PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis.

Pende D, Bottino C, Castriconi R, Cantoni C, Marcenaro S, Rivera P, Spaggiari GM, Dondero A, Carnemolla B, Reymond N, Mingari MC, Lopez M, Moretta L, Moretta A.

Mol Immunol. 2005 Feb;42(4):463-9.

PMID:
15607800
15.

Decreased expression of DNAM-1 on NK cells from acute myeloid leukemia patients.

Sanchez-Correa B, Gayoso I, Bergua JM, Casado JG, Morgado S, Solana R, Tarazona R.

Immunol Cell Biol. 2012 Jan;90(1):109-15. doi: 10.1038/icb.2011.15. Epub 2011 Mar 8.

PMID:
21383766
16.

Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112).

Pende D, Spaggiari GM, Marcenaro S, Martini S, Rivera P, Capobianco A, Falco M, Lanino E, Pierri I, Zambello R, Bacigalupo A, Mingari MC, Moretta A, Moretta L.

Blood. 2005 Mar 1;105(5):2066-73. Epub 2004 Nov 9.

17.

Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity.

Dunn C, Chalupny NJ, Sutherland CL, Dosch S, Sivakumar PV, Johnson DC, Cosman D.

J Exp Med. 2003 Jun 2;197(11):1427-39.

18.

The Role of T Cell Costimulation via DNAM-1 in Kidney Transplantation.

Kraus AK, Chen J, Edenhofer I, Ravens I, Gaspert A, Cippà PE, Mueller S, Wuthrich RP, Segerer S, Bernhardt G, Fehr T.

PLoS One. 2016 Feb 3;11(2):e0147951. doi: 10.1371/journal.pone.0147951. eCollection 2016.

19.

Identification and functional analysis of ligands for natural killer cell activating receptors in colon carcinoma.

Zhang Z, Su T, He L, Wang H, Ji G, Liu X, Zhang Y, Dong G.

Tohoku J Exp Med. 2012 Jan;226(1):59-68. doi: 10.6120/tjem.226.59.

20.

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