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Items: 1 to 20 of 254

1.

Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes.

Pasini D, Malatesta M, Jung HR, Walfridsson J, Willer A, Olsson L, Skotte J, Wutz A, Porse B, Jensen ON, Helin K.

Nucleic Acids Res. 2010 Aug;38(15):4958-69. doi: 10.1093/nar/gkq244. Epub 2010 Apr 12.

3.

The polycomb group protein Suz12 is required for embryonic stem cell differentiation.

Pasini D, Bracken AP, Hansen JB, Capillo M, Helin K.

Mol Cell Biol. 2007 May;27(10):3769-79. Epub 2007 Mar 5.

4.

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2.

Pasini D, Hansen KH, Christensen J, Agger K, Cloos PA, Helin K.

Genes Dev. 2008 May 15;22(10):1345-55. doi: 10.1101/gad.470008.

5.

Quantitative mass spectrometry of histones H3.2 and H3.3 in Suz12-deficient mouse embryonic stem cells reveals distinct, dynamic post-translational modifications at Lys-27 and Lys-36.

Jung HR, Pasini D, Helin K, Jensen ON.

Mol Cell Proteomics. 2010 May;9(5):838-50. doi: 10.1074/mcp.M900489-MCP200. Epub 2010 Feb 11.

6.

Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27.

Kirmizis A, Bartley SM, Kuzmichev A, Margueron R, Reinberg D, Green R, Farnham PJ.

Genes Dev. 2004 Jul 1;18(13):1592-605.

7.

Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8.

Fujimura Y, Isono K, Vidal M, Endoh M, Kajita H, Mizutani-Koseki Y, Takihara Y, van Lohuizen M, Otte A, Jenuwein T, Deschamps J, Koseki H.

Development. 2006 Jun;133(12):2371-81. Epub 2006 May 10. Erratum in: Development. 2014 Sep;141(17):3431-6.

8.

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells.

Pasini D, Cloos PA, Walfridsson J, Olsson L, Bukowski JP, Johansen JV, Bak M, Tommerup N, Rappsilber J, Helin K.

Nature. 2010 Mar 11;464(7286):306-10. doi: 10.1038/nature08788.

PMID:
20075857
9.

Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation.

Yuan W, Wu T, Fu H, Dai C, Wu H, Liu N, Li X, Xu M, Zhang Z, Niu T, Han Z, Chai J, Zhou XJ, Gao S, Zhu B.

Science. 2012 Aug 24;337(6097):971-5. doi: 10.1126/science.1225237.

11.

FOXC1, a target of polycomb, inhibits metastasis of breast cancer cells.

Du J, Li L, Ou Z, Kong C, Zhang Y, Dong Z, Zhu S, Jiang H, Shao Z, Huang B, Lu J.

Breast Cancer Res Treat. 2012 Jan;131(1):65-73. doi: 10.1007/s10549-011-1396-3. Epub 2011 Apr 5. Erratum in: Breast Cancer Res Treat. 2016 Apr;156(3):609-10.

PMID:
21465172
12.

Pluripotency factors and Polycomb Group proteins repress aryl hydrocarbon receptor expression in murine embryonic stem cells.

Ko CI, Wang Q, Fan Y, Xia Y, Puga A.

Stem Cell Res. 2014 Jan;12(1):296-308. doi: 10.1016/j.scr.2013.11.007. Epub 2013 Nov 16.

13.

Additional sex combs-like 2 is required for polycomb repressive complex 2 binding at select targets.

Lai HL, Wang QT.

PLoS One. 2013 Sep 9;8(9):e73983. doi: 10.1371/journal.pone.0073983. eCollection 2013.

14.

The polycomb repressive complex 2 is a potential target of SUMO modifications.

Riising EM, Boggio R, Chiocca S, Helin K, Pasini D.

PLoS One. 2008 Jul 16;3(7):e2704. doi: 10.1371/journal.pone.0002704.

15.

Inner workings and regulatory inputs that control Polycomb repressive complex 2.

O'Meara MM, Simon JA.

Chromosoma. 2012 Jun;121(3):221-34. doi: 10.1007/s00412-012-0361-1. Epub 2012 Feb 19. Review.

16.
17.

Role of histone H3 lysine 27 methylation in Polycomb-group silencing.

Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, Tempst P, Jones RS, Zhang Y.

Science. 2002 Nov 1;298(5595):1039-43. Epub 2002 Sep 26.

18.

Histone H3 modifications associated with differentiation and long-term culture of mesenchymal adipose stem cells.

Noer A, Lindeman LC, Collas P.

Stem Cells Dev. 2009 Jun;18(5):725-36. doi: 10.1089/scd.2008.0189.

PMID:
18771397
19.

Polycomb group protein-associated chromatin is reproduced in post-mitotic G1 phase and is required for S phase progression.

Aoto T, Saitoh N, Sakamoto Y, Watanabe S, Nakao M.

J Biol Chem. 2008 Jul 4;283(27):18905-15. doi: 10.1074/jbc.M709322200. Epub 2008 May 2.

20.

CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing.

Tie F, Banerjee R, Stratton CA, Prasad-Sinha J, Stepanik V, Zlobin A, Diaz MO, Scacheri PC, Harte PJ.

Development. 2009 Sep;136(18):3131-41. doi: 10.1242/dev.037127.

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