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Items: 1 to 20 of 120


Progression of geographic atrophy and genotype in age-related macular degeneration.

Klein ML, Ferris FL 3rd, Francis PJ, Lindblad AS, Chew EY, Hamon SC, Ott J.

Ophthalmology. 2010 Aug;117(8):1554-9, 1559.e1. doi: 10.1016/j.ophtha.2009.12.012. Epub 2010 Apr 9.


Growth of geographic atrophy on fundus autofluorescence and polymorphisms of CFH, CFB, C3, FHR1-3, and ARMS2 in age-related macular degeneration.

Caire J, Recalde S, Velazquez-Villoria A, Garcia-Garcia L, Reiter N, Anter J, Fernandez-Robredo P, Alfredo García-Layana; Spanish Multicenter Group on AMD.

JAMA Ophthalmol. 2014 May;132(5):528-34.


Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss.

Francis PJ, Hamon SC, Ott J, Weleber RG, Klein ML.

J Med Genet. 2009 May;46(5):300-7. doi: 10.1136/jmg.2008.062737. Epub 2008 Nov 17.


Genetic analysis of simultaneous geographic atrophy and choroidal neovascularization.

Grob S, Luo J, Hughes G, Lee C, Zhou X, Lee J, Du H, Ferreyra H, Freeman WR, Kozak I, Zhang K.

Eye (Lond). 2012 Aug;26(8):1106-13. doi: 10.1038/eye.2012.107. Epub 2012 Jun 15.


CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration.

Klein ML, Francis PJ, Rosner B, Reynolds R, Hamon SC, Schultz DW, Ott J, Seddon JM.

Ophthalmology. 2008 Jun;115(6):1019-25. doi: 10.1016/j.ophtha.2008.01.036.


Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration.

Seddon JM, Francis PJ, George S, Schultz DW, Rosner B, Klein ML.

JAMA. 2007 Apr 25;297(16):1793-800. Erratum in: JAMA. 2007 Jun 20;297(23):2585.


Inclusion of genotype with fundus phenotype improves accuracy of predicting choroidal neovascularization and geographic atrophy.

Perlee LT, Bansal AT, Gehrs K, Heier JS, Csaky K, Allikmets R, Oeth P, Paladino T, Farkas DH, Rawlings PL, Hageman GS.

Ophthalmology. 2013 Sep;120(9):1880-92. doi: 10.1016/j.ophtha.2013.02.007. Epub 2013 Mar 21.


CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD.

Scholl HP, Fleckenstein M, Fritsche LG, Schmitz-Valckenberg S, Göbel A, Adrion C, Herold C, Keilhauer CN, Mackensen F, Mössner A, Pauleikhoff D, Weinberger AW, Mansmann U, Holz FG, Becker T, Weber BH.

PLoS One. 2009 Oct 12;4(10):e7418. doi: 10.1371/journal.pone.0007418.


The ARMS2 A69S variant and bilateral advanced age-related macular degeneration.

Schwartz SG, Agarwal A, Kovach JL, Gallins PJ, Cade W, Postel EA, Wang G, Ayala-Haedo J, Spencer KM, Haines JL, Pericak-Vance MA, Scott WK.

Retina. 2012 Sep;32(8):1486-91. doi: 10.1097/IAE.0b013e318240a540.


Incidence and progression of geographic atrophy: observations from a population-based cohort.

Joachim N, Mitchell P, Kifley A, Rochtchina E, Hong T, Wang JJ.

Ophthalmology. 2013 Oct;120(10):2042-50. doi: 10.1016/j.ophtha.2013.03.029. Epub 2013 May 22.


No clinically significant association between CFH and ARMS2 genotypes and response to nutritional supplements: AREDS report number 38.

Chew EY, Klein ML, Clemons TE, Agrón E, Ratnapriya R, Edwards AO, Fritsche LG, Swaroop A, Abecasis GR; Age-Related Eye Disease Study Research Group.

Ophthalmology. 2014 Nov;121(11):2173-80. doi: 10.1016/j.ophtha.2014.05.008. Epub 2014 Jun 26.


The association between macular pigment optical density and CFH, ARMS2, C2/BF, and C3 genotype.

Loane E, Nolan JM, McKay GJ, Beatty S.

Exp Eye Res. 2011 Nov;93(5):592-8. doi: 10.1016/j.exer.2011.07.005. Epub 2011 Jul 27.


Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16.

Keenan TD, Agrón E, Domalpally A, Clemons TE, van Asten F, Wong WT, Danis RG, Sadda S, Rosenfeld PJ, Klein ML, Ratnapriya R, Swaroop A, Ferris FL 3rd, Chew EY; AREDS2 Research Group.

Ophthalmology. 2018 Dec;125(12):1913-1928. doi: 10.1016/j.ophtha.2018.05.028. Epub 2018 Jul 27.


Multilocus analysis of age-related macular degeneration.

Bergeron-Sawitzke J, Gold B, Olsh A, Schlotterbeck S, Lemon K, Visvanathan K, Allikmets R, Dean M.

Eur J Hum Genet. 2009 Sep;17(9):1190-9. doi: 10.1038/ejhg.2009.23. Epub 2009 Mar 4.


Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17.

Yu JJ, Agrón E, Clemons TE, Domalpally A, van Asten F, Keenan TD, Cukras C, Chew EY; Age-Related Eye Disease Study 2 Research Group.

Ophthalmology. 2019 Feb;126(2):261-273. doi: 10.1016/j.ophtha.2018.08.017. Epub 2018 Aug 22.


Association of CFH, LOC387715, and HTRA1 polymorphisms with exudative age-related macular degeneration in a northern Chinese population.

Xu Y, Guan N, Xu J, Yang X, Ma K, Zhou H, Zhang F, Snellingen T, Jiao Y, Liu X, Wang N, Liu N.

Mol Vis. 2008 Jul 28;14:1373-81.


Single-Nucleotide Polymorphisms Associated With Age-Related Macular Degeneration and Lesion Phenotypes in the Comparison of Age-Related Macular Degeneration Treatments Trials.

Maguire MG, Ying GS, Jaffe GJ, Toth CA, Daniel E, Grunwald J, Martin DF, Hagstrom SA; CATT Research Group.

JAMA Ophthalmol. 2016 Jun 1;134(6):674-81. doi: 10.1001/jamaophthalmol.2016.0669.


CFH haplotypes and ARMS2, C2, C3, and CFB alleles show association with susceptibility to age-related macular degeneration in Mexicans.

Contreras AV, Zenteno JC, Fernández-López JC, Rodríguez-Corona U, Falfán-Valencia R, Sebastian L, Morales F, Ochoa-Contreras D, Carnevale A, Silva-Zolezzi I.

Mol Vis. 2014 Jan 14;20:105-16. eCollection 2014.


Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables.

Seddon JM, Reynolds R, Maller J, Fagerness JA, Daly MJ, Rosner B.

Invest Ophthalmol Vis Sci. 2009 May;50(5):2044-53. doi: 10.1167/iovs.08-3064. Epub 2008 Dec 30.

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