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Decreased serum vitamin D levels in children with asthma are associated with increased corticosteroid use.

Searing DA, Zhang Y, Murphy JR, Hauk PJ, Goleva E, Leung DY.

J Allergy Clin Immunol. 2010 May;125(5):995-1000. doi: 10.1016/j.jaci.2010.03.008. Epub 2010 Apr 9.


Anti-inflammatory and corticosteroid-enhancing actions of vitamin D in monocytes of patients with steroid-resistant and those with steroid-sensitive asthma.

Zhang Y, Leung DY, Goleva E.

J Allergy Clin Immunol. 2014 Jun;133(6):1744-52.e1. doi: 10.1016/j.jaci.2013.12.004. Epub 2014 Jan 11.


Steroid requirements and immune associations with vitamin D are stronger in children than adults with asthma.

Goleva E, Searing DA, Jackson LP, Richers BN, Leung DY.

J Allergy Clin Immunol. 2012 May;129(5):1243-51. doi: 10.1016/j.jaci.2012.01.044. Epub 2012 Feb 11.


Vitamin D levels, lung function, and steroid response in adult asthma.

Sutherland ER, Goleva E, Jackson LP, Stevens AD, Leung DY.

Am J Respir Crit Care Med. 2010 Apr 1;181(7):699-704. doi: 10.1164/rccm.200911-1710OC. Epub 2010 Jan 14.


Usefulness of PBMCs to predict clinical response to corticosteroids in asthmatic patients.

Goleva E, Jackson LP, Gleason M, Leung DY.

J Allergy Clin Immunol. 2012 Mar;129(3):687-693.e1. doi: 10.1016/j.jaci.2011.12.001. Epub 2012 Jan 10.


Enhanced production of IL-17A in patients with severe asthma is inhibited by 1α,25-dihydroxyvitamin D3 in a glucocorticoid-independent fashion.

Nanzer AM, Chambers ES, Ryanna K, Richards DF, Black C, Timms PM, Martineau AR, Griffiths CJ, Corrigan CJ, Hawrylowicz CM.

J Allergy Clin Immunol. 2013 Aug;132(2):297-304.e3. doi: 10.1016/j.jaci.2013.03.037. Epub 2013 May 15.


Defective IL-10 expression and in vitro steroid-induced IL-17A in paediatric severe therapy-resistant asthma.

Gupta A, Dimeloe S, Richards DF, Chambers ES, Black C, Urry Z, Ryanna K, Xystrakis E, Bush A, Saglani S, Hawrylowicz CM.

Thorax. 2014 Jun;69(6):508-15. doi: 10.1136/thoraxjnl-2013-203421. Epub 2013 Dec 17.


Effect of vitamin D and inhaled corticosteroid treatment on lung function in children.

Wu AC, Tantisira K, Li L, Fuhlbrigge AL, Weiss ST, Litonjua A; Childhood Asthma Management Program Research Group.

Am J Respir Crit Care Med. 2012 Sep 15;186(6):508-13. Epub 2012 Jul 12.


Mechanisms of glucocorticoid reduction in asthmatic subjects treated with intravenous immunoglobulin.

Spahn JD, Leung DY, Chan MT, Szefler SJ, Gelfand EW.

J Allergy Clin Immunol. 1999 Mar;103(3 Pt 1):421-6.


Body mass and glucocorticoid response in asthma.

Sutherland ER, Goleva E, Strand M, Beuther DA, Leung DY.

Am J Respir Crit Care Med. 2008 Oct 1;178(7):682-7. doi: 10.1164/rccm.200801-076OC. Epub 2008 Jul 17.


Vitamin D deficiency as a strong predictor of asthma in children.

Bener A, Ehlayel MS, Tulic MK, Hamid Q.

Int Arch Allergy Immunol. 2012;157(2):168-75. doi: 10.1159/000323941. Epub 2011 Oct 6.


Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma.

Gupta A, Sjoukes A, Richards D, Banya W, Hawrylowicz C, Bush A, Saglani S.

Am J Respir Crit Care Med. 2011 Dec 15;184(12):1342-9. doi: 10.1164/rccm.201107-1239OC. Epub 2011 Sep 8.


Vitamin D enhances glucocorticoid action in human monocytes: involvement of granulocyte-macrophage colony-stimulating factor and mediator complex subunit 14.

Zhang Y, Leung DY, Goleva E.

J Biol Chem. 2013 May 17;288(20):14544-53. doi: 10.1074/jbc.M112.427054. Epub 2013 Apr 9.


Obesity impairs apoptotic cell clearance in asthma.

Fernandez-Boyanapalli R, Goleva E, Kolakowski C, Min E, Day B, Leung DY, Riches DW, Bratton DL, Sutherland ER.

J Allergy Clin Immunol. 2013 Apr;131(4):1041-7, 1047.e1-3. doi: 10.1016/j.jaci.2012.09.028. Epub 2012 Nov 13.


1,25-dihydroxyvitamin D3 and dexamethasone increase interleukin-10 production in CD4+ T cells from patients with Crohn's disease.

Bartels LE, Jørgensen SP, Agnholt J, Kelsen J, Hvas CL, Dahlerup JF.

Int Immunopharmacol. 2007 Dec 15;7(13):1755-64. Epub 2007 Oct 5.


Vitamin D levels and vitamin D receptor gene polymorphisms in asthmatic children: a case-control study.

Einisman H, Reyes ML, Angulo J, Cerda J, López-Lastra M, Castro-Rodriguez JA.

Pediatr Allergy Immunol. 2015 Sep;26(6):545-50. doi: 10.1111/pai.12409. Epub 2015 Jun 17.


Individual variations in lymphocyte-responses to glucocorticoids in patients with bronchial asthma: comparison of potencies for five glucocorticoids.

Hirano T, Homma M, Oka K, Tsushima H, Niitsuma T, Hayashi T.

Immunopharmacology. 1998 Jul;40(1):57-66.


Baseline serum 25-hydroxyvitamin d levels in men undergoing radical prostatectomy: is there an association with adverse pathologic features?

Berg WT, Shapiro EY, Rothberg MB, Bergman A, Scarberry K, Wambi C, Patel T, Badani KK.

Clin Genitourin Cancer. 2014 Oct;12(5):330-4. doi: 10.1016/j.clgc.2014.02.004. Epub 2014 Feb 20.


Impaired anti-inflammatory action of glucocorticoid in neutrophil from patients with steroid-resistant asthma.

Wang M, Gao P, Wu X, Chen Y, Feng Y, Yang Q, Xu Y, Zhao J, Xie J.

Respir Res. 2016 Nov 16;17(1):153.


Rhinovirus infection causes steroid resistance in airway epithelium through nuclear factor κB and c-Jun N-terminal kinase activation.

Papi A, Contoli M, Adcock IM, Bellettato C, Padovani A, Casolari P, Stanciu LA, Barnes PJ, Johnston SL, Ito K, Caramori G.

J Allergy Clin Immunol. 2013 Nov;132(5):1075-1085.e6. doi: 10.1016/j.jaci.2013.05.028. Epub 2013 Jul 18.


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