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Items: 1 to 20 of 78

1.

A canonical cation-π interaction stabilizes the agonist conformation of estrogen-like nuclear receptors.

Queralt-Rosinach N, Mestres J.

Eur Biophys J. 2010 Oct;39(11):1471-5. doi: 10.1007/s00249-010-0602-2. Epub 2010 Apr 3.

PMID:
20364341
2.

X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.

Wang L, Zuercher WJ, Consler TG, Lambert MH, Miller AB, Orband-Miller LA, McKee DD, Willson TM, Nolte RT.

J Biol Chem. 2006 Dec 8;281(49):37773-81. Epub 2006 Sep 21.

3.

Ligand-induced stabilization of PPARgamma monitored by NMR spectroscopy: implications for nuclear receptor activation.

Johnson BA, Wilson EM, Li Y, Moller DE, Smith RG, Zhou G.

J Mol Biol. 2000 Apr 28;298(2):187-94.

PMID:
10764590
4.

Biochemical and NMR mapping of the interface between CREB-binding protein and ligand binding domains of nuclear receptor: beyond the LXXLL motif.

Klein FA, Atkinson RA, Potier N, Moras D, Cavarelli J.

J Biol Chem. 2005 Feb 18;280(7):5682-92. Epub 2004 Nov 12.

5.

Local motifs involved in the canonical structure of the ligand-binding domain in the nuclear receptor superfamily.

Tsuji M.

J Struct Biol. 2014 Mar;185(3):355-65. doi: 10.1016/j.jsb.2013.12.007. Epub 2013 Dec 19.

PMID:
24361687
6.

Exploring Binding Mechanisms in Nuclear Hormone Receptors by Monte Carlo and X-ray-derived Motions.

Grebner C, Lecina D, Gil V, Ulander J, Hansson P, Dellsen A, Tyrchan C, Edman K, Hogner A, Guallar V.

Biophys J. 2017 Mar 28;112(6):1147-1156. doi: 10.1016/j.bpj.2017.02.004.

7.
9.

Antagonist- and inverse agonist-driven interactions of the vitamin D receptor and the constitutive androstane receptor with corepressor protein.

Lempiäinen H, Molnár F, Macias Gonzalez M, Peräkylä M, Carlberg C.

Mol Endocrinol. 2005 Sep;19(9):2258-72. Epub 2005 May 19.

PMID:
15905360
10.

Metal-dependent folding and stability of nuclear hormone receptor DNA-binding domains.

Low LY, Hernández H, Robinson CV, O'Brien R, Grossmann JG, Ladbury JE, Luisi B.

J Mol Biol. 2002 May 24;319(1):87-106.

PMID:
12051939
11.

Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors.

Xu HE, Lambert MH, Montana VG, Plunket KD, Moore LB, Collins JL, Oplinger JA, Kliewer SA, Gampe RT Jr, McKee DD, Moore JT, Willson TM.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13919-24. Epub 2001 Nov 6.

12.

Molecular determinants of LXRalpha agonism.

Wang M, Thomas J, Burris TP, Schkeryantz J, Michael LF.

J Mol Graph Model. 2003 Nov;22(2):173-81.

PMID:
12932788
13.

The coactivator LXXLL nuclear receptor recognition motif.

Savkur RS, Burris TP.

J Pept Res. 2004 Mar;63(3):207-12. Review.

PMID:
15049832
14.

Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs.

Frank C, Molnár F, Matilainen M, Lempiäinen H, Carlberg C.

J Biol Chem. 2004 Aug 6;279(32):33558-66. Epub 2004 May 19.

15.

Molecular determinants for agonist and antagonist binding to steroid nuclear receptors.

Wurtz JM, Moras D.

Ernst Schering Res Found Workshop. 2001;(34):167-80. Review. No abstract available.

PMID:
11394044
16.

Structural and functional insights into nuclear receptor signaling.

Jin L, Li Y.

Adv Drug Deliv Rev. 2010 Oct 30;62(13):1218-26. doi: 10.1016/j.addr.2010.08.007. Epub 2010 Aug 17. Review.

17.

Structure of REV-ERBβ ligand-binding domain bound to a porphyrin antagonist.

Matta-Camacho E, Banerjee S, Hughes TS, Solt LA, Wang Y, Burris TP, Kojetin DJ.

J Biol Chem. 2014 Jul 18;289(29):20054-66. doi: 10.1074/jbc.M113.545111. Epub 2014 May 28.

18.

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha.

Xu HE, Stanley TB, Montana VG, Lambert MH, Shearer BG, Cobb JE, McKee DD, Galardi CM, Plunket KD, Nolte RT, Parks DJ, Moore JT, Kliewer SA, Willson TM, Stimmel JB.

Nature. 2002 Feb 14;415(6873):813-7.

PMID:
11845213
19.

Conformational adaptation of nuclear receptor ligand binding domains to agonists: potential for novel approaches to ligand design.

Togashi M, Borngraeber S, Sandler B, Fletterick RJ, Webb P, Baxter JD.

J Steroid Biochem Mol Biol. 2005 Feb;93(2-5):127-37. Epub 2005 Feb 19. Review.

PMID:
15860255
20.

Structural determination of estrogen-related receptor gamma in the presence of phenol derivative compounds.

Abad MC, Askari H, O'Neill J, Klinger AL, Milligan C, Lewandowski F, Springer B, Spurlino J, Rentzeperis D.

J Steroid Biochem Mol Biol. 2008 Jan;108(1-2):44-54. Epub 2007 Sep 14.

PMID:
17964775

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