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Items: 1 to 20 of 118

1.

Assessment of candidate biomarkers of drug-induced hepatobiliary injury in preclinical toxicity studies.

Adler M, Hoffmann D, Ellinger-Ziegelbauer H, Hewitt P, Matheis K, Mulrane L, Gallagher WM, Callanan JJ, Suter L, Fountoulakis MM, Dekant W, Mally A.

Toxicol Lett. 2010 Jun 16;196(1):1-11. doi: 10.1016/j.toxlet.2010.03.018. Epub 2010 Apr 1.

PMID:
20362651
2.

The discovery and development of proteomic safety biomarkers for the detection of drug-induced liver toxicity.

Amacher DE.

Toxicol Appl Pharmacol. 2010 May 15;245(1):134-42. doi: 10.1016/j.taap.2010.02.011. Epub 2010 Feb 26. Review.

PMID:
20219512
3.

Cytochrome c: a non-invasive biomarker of drug-induced liver injury.

Miller TJ, Knapton A, Adeyemo O, Noory L, Weaver J, Hanig JP.

J Appl Toxicol. 2008 Oct;28(7):815-28. doi: 10.1002/jat.1347.

PMID:
18418843
4.

Evaluation of the usefulness of novel biomarkers for drug-induced acute kidney injury in beagle dogs.

Zhou X, Ma B, Lin Z, Qu Z, Huo Y, Wang J, Li B.

Toxicol Appl Pharmacol. 2014 Oct 1;280(1):30-5. doi: 10.1016/j.taap.2014.07.002. Epub 2014 Jul 14.

PMID:
25034533
5.

Diagnostic performance of traditional hepatobiliary biomarkers of drug-induced liver injury in the rat.

Ennulat D, Magid-Slav M, Rehm S, Tatsuoka KS.

Toxicol Sci. 2010 Aug;116(2):397-412. doi: 10.1093/toxsci/kfq144. Epub 2010 May 13.

6.

Urinary clusterin, cystatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injury.

Dieterle F, Perentes E, Cordier A, Roth DR, Verdes P, Grenet O, Pantano S, Moulin P, Wahl D, Mahl A, End P, Staedtler F, Legay F, Carl K, Laurie D, Chibout SD, Vonderscher J, Maurer G.

Nat Biotechnol. 2010 May;28(5):463-9. doi: 10.1038/nbt.1622.

PMID:
20458316
7.

Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury.

Mishra J, Ma Q, Prada A, Mitsnefes M, Zahedi K, Yang J, Barasch J, Devarajan P.

J Am Soc Nephrol. 2003 Oct;14(10):2534-43.

8.

The current state of serum biomarkers of hepatotoxicity.

Ozer J, Ratner M, Shaw M, Bailey W, Schomaker S.

Toxicology. 2008 Mar 20;245(3):194-205. doi: 10.1016/j.tox.2007.11.021. Epub 2007 Dec 5. Review.

PMID:
18291570
9.

Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure.

Yndestad A, Landrø L, Ueland T, Dahl CP, Flo TH, Vinge LE, Espevik T, Frøland SS, Husberg C, Christensen G, Dickstein K, Kjekshus J, Øie E, Gullestad L, Aukrust P.

Eur Heart J. 2009 May;30(10):1229-36. doi: 10.1093/eurheartj/ehp088. Epub 2009 Mar 26.

10.

Is toxicogenomics a more reliable and sensitive biomarker than conventional indicators from rats to predict drug-induced liver injury in humans?

Zhang M, Chen M, Tong W.

Chem Res Toxicol. 2012 Jan 13;25(1):122-9. doi: 10.1021/tx200320e. Epub 2011 Dec 13.

PMID:
22122743
11.

A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function.

Ozer JS, Dieterle F, Troth S, Perentes E, Cordier A, Verdes P, Staedtler F, Mahl A, Grenet O, Roth DR, Wahl D, Legay F, Holder D, Erdos Z, Vlasakova K, Jin H, Yu Y, Muniappa N, Forest T, Clouse HK, Reynolds S, Bailey WJ, Thudium DT, Topper MJ, Skopek TR, Sina JF, Glaab WE, Vonderscher J, Maurer G, Chibout SD, Sistare FD, Gerhold DL.

Nat Biotechnol. 2010 May;28(5):486-94. doi: 10.1038/nbt.1627.

PMID:
20458319
12.

Urinary IL-18 and NGAL as early predictive biomarkers in contrast-induced nephropathy after coronary angiography.

Ling W, Zhaohui N, Ben H, Leyi G, Jianping L, Huili D, Jiaqi Q.

Nephron Clin Pract. 2008;108(3):c176-81. doi: 10.1159/000117814. Epub 2008 Feb 21.

PMID:
18287807
13.

NGAL is an early predictive biomarker of contrast-induced nephropathy in children.

Hirsch R, Dent C, Pfriem H, Allen J, Beekman RH 3rd, Ma Q, Dastrala S, Bennett M, Mitsnefes M, Devarajan P.

Pediatr Nephrol. 2007 Dec;22(12):2089-95. Epub 2007 Sep 14.

PMID:
17874137
14.

Urine neutrophil gelatinase-associated lipocalin and interleukin-18 predict acute kidney injury after cardiac surgery.

Xin C, Yulong X, Yu C, Changchun C, Feng Z, Xinwei M.

Ren Fail. 2008;30(9):904-13. doi: 10.1080/08860220802359089.

PMID:
18925531
15.

Performance of novel kidney biomarkers in preclinical toxicity studies.

Hoffmann D, Adler M, Vaidya VS, Rached E, Mulrane L, Gallagher WM, Callanan JJ, Gautier JC, Matheis K, Staedtler F, Dieterle F, Brandenburg A, Sposny A, Hewitt P, Ellinger-Ziegelbauer H, Bonventre JV, Dekant W, Mally A.

Toxicol Sci. 2010 Jul;116(1):8-22. doi: 10.1093/toxsci/kfq029. Epub 2010 Jan 29.

17.

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials.

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. doi: 10.1016/j.fct.2008.02.008. Epub 2008 Feb 13. Review.

PMID:
18328408
18.

Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy.

Amacher DE, Adler R, Herath A, Townsend RR.

Clin Chem. 2005 Oct;51(10):1796-803. Epub 2005 Aug 11.

19.
20.

An in vitro assay to assess transporter-based cholestatic hepatotoxicity using sandwich-cultured rat hepatocytes.

Ansede JH, Smith WR, Perry CH, St Claire RL 3rd, Brouwer KR.

Drug Metab Dispos. 2010 Feb;38(2):276-80. doi: 10.1124/dmd.109.028407. Epub 2009 Nov 12.

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