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Items: 1 to 20 of 89

1.

Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins.

Wang L, Gordon RA, Huynh L, Su X, Park Min KH, Han J, Arthur JS, Kalliolias GD, Ivashkiv LB.

Immunity. 2010 Apr 23;32(4):518-30. doi: 10.1016/j.immuni.2010.03.014. Epub 2010 Apr 1.

2.

ITAM-coupled receptors inhibit IFNAR signaling and alter macrophage responses to TLR4 and Listeria monocytogenes.

Huynh L, Wang L, Shi C, Park-Min KH, Ivashkiv LB.

J Immunol. 2012 Apr 1;188(7):3447-57. doi: 10.4049/jimmunol.1102211. Epub 2012 Feb 24.

3.

'Tuning' of type I interferon-induced Jak-STAT1 signaling by calcium-dependent kinases in macrophages.

Wang L, Tassiulas I, Park-Min KH, Reid AC, Gil-Henn H, Schlessinger J, Baron R, Zhang JJ, Ivashkiv LB.

Nat Immunol. 2008 Feb;9(2):186-93. Epub 2007 Dec 16.

PMID:
18084294
4.

Anti-inflammatory actions of Syk inhibitors in macrophages involve non-specific inhibition of toll-like receptors-mediated JNK signaling pathway.

Lin YC, Huang DY, Chu CL, Lin WW.

Mol Immunol. 2010 Apr;47(7-8):1569-78. doi: 10.1016/j.molimm.2010.01.008.

PMID:
20138367
5.

Cross-regulation of signaling by ITAM-associated receptors.

Ivashkiv LB.

Nat Immunol. 2009 Apr;10(4):340-7. doi: 10.1038/ni.1706. Epub 2009 Mar 19. Review.

6.

β(2) integrins inhibit TLR responses by regulating NF-κB pathway and p38 MAPK activation.

Yee NK, Hamerman JA.

Eur J Immunol. 2013 Mar;43(3):779-92. doi: 10.1002/eji.201242550. Epub 2013 Feb 11.

7.

Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation.

Hu X, Chen J, Wang L, Ivashkiv LB.

J Leukoc Biol. 2007 Aug;82(2):237-43. Epub 2007 May 14. Review.

PMID:
17502339
8.

Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12.

Hamerman JA, Tchao NK, Lowell CA, Lanier LL.

Nat Immunol. 2005 Jun;6(6):579-86. Epub 2005 May 15. Erratum in: Nat Immunol. 2009 Feb;10(2):223. Dosage error in article text.

9.

Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs.

Mócsai A, Abram CL, Jakus Z, Hu Y, Lanier LL, Lowell CA.

Nat Immunol. 2006 Dec;7(12):1326-33. Epub 2006 Nov 5.

10.

B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K.

Ni M, MacFarlane AW 4th, Toft M, Lowell CA, Campbell KS, Hamerman JA.

Proc Natl Acad Sci U S A. 2012 Jan 3;109(1):267-72. doi: 10.1073/pnas.1111957108. Epub 2011 Dec 20.

11.

PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling.

Zarbock A, Abram CL, Hundt M, Altman A, Lowell CA, Ley K.

J Exp Med. 2008 Sep 29;205(10):2339-47. doi: 10.1084/jem.20072660. Epub 2008 Sep 15.

14.

Analysis of the linker for activation of T cells and the linker for activation of B cells in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire.

Whittaker GC, Burshtyn DN, Orr SJ, Quigley L, Hodge DL, Pascal V, Zhang W, McVicar DW.

Blood. 2008 Oct 1;112(7):2869-77. doi: 10.1182/blood-2007-11-121590. Epub 2008 Jul 21.

15.

Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells.

Baetz A, Frey M, Heeg K, Dalpke AH.

J Biol Chem. 2004 Dec 24;279(52):54708-15. Epub 2004 Oct 18.

16.

Increased TLR responses in dendritic cells lacking the ITAM-containing adapters DAP12 and FcRgamma.

Chu CL, Yu YL, Shen KY, Lowell CA, Lanier LL, Hamerman JA.

Eur J Immunol. 2008 Jan;38(1):166-73.

17.

The WNT signaling pathway contributes to dectin-1-dependent inhibition of Toll-like receptor-induced inflammatory signature.

Trinath J, Holla S, Mahadik K, Prakhar P, Singh V, Balaji KN.

Mol Cell Biol. 2014 Dec 1;34(23):4301-14. doi: 10.1128/MCB.00641-14. Epub 2014 Sep 22.

18.

Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b.

Han C, Jin J, Xu S, Liu H, Li N, Cao X.

Nat Immunol. 2010 Aug;11(8):734-42. doi: 10.1038/ni.1908. Epub 2010 Jul 18.

PMID:
20639876
19.

Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12.

Hamerman JA, Jarjoura JR, Humphrey MB, Nakamura MC, Seaman WE, Lanier LL.

J Immunol. 2006 Aug 15;177(4):2051-5.

20.

TLR-mediated signaling pathways circumvent the requirement for DAP12 in mast cells for the induction of inflammatory mediator release.

Smrz D, Iwaki S, McVicar DW, Metcalfe DD, Gilfillan AM.

Eur J Immunol. 2010 Dec;40(12):3557-69. doi: 10.1002/eji.201040573. Epub 2010 Nov 11.

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