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Items: 1 to 20 of 245

1.

The primary cilium as a Hedgehog signal transduction machine.

Goetz SC, Ocbina PJ, Anderson KV.

Methods Cell Biol. 2009;94:199-222. doi: 10.1016/S0091-679X(08)94010-3. Epub 2009 Dec 23.

2.

Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts.

Ocbina PJ, Anderson KV.

Dev Dyn. 2008 Aug;237(8):2030-8. doi: 10.1002/dvdy.21551.

3.

Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis.

Yang N, Li L, Eguether T, Sundberg JP, Pazour GJ, Chen J.

Development. 2015 Jun 15;142(12):2194-202. doi: 10.1242/dev.115261. Epub 2015 May 28. Erratum in: Development. 2015 Aug 15;142(16):2860.

4.

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.

Wen X, Lai CK, Evangelista M, Hongo JA, de Sauvage FJ, Scales SJ.

Mol Cell Biol. 2010 Apr;30(8):1910-22. doi: 10.1128/MCB.01089-09. Epub 2010 Feb 12.

5.

Cilia and Hedgehog responsiveness in the mouse.

Huangfu D, Anderson KV.

Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11325-30. Epub 2005 Aug 1.

6.

Hedgehog signaling requires motile cilia in the sea urchin.

Warner JF, McCarthy AM, Morris RL, McClay DR.

Mol Biol Evol. 2014 Jan;31(1):18-22. doi: 10.1093/molbev/mst176. Epub 2013 Oct 11.

7.

Hedgehog-stimulated chemotaxis is mediated by smoothened located outside the primary cilium.

Bijlsma MF, Damhofer H, Roelink H.

Sci Signal. 2012 Aug 21;5(238):ra60. doi: 10.1126/scisignal.2002798.

8.

Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation.

Wang Y, Zhou Z, Walsh CT, McMahon AP.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2623-8. doi: 10.1073/pnas.0812110106. Epub 2009 Feb 5.

9.

Cilia-mediated hedgehog signaling in Drosophila.

Kuzhandaivel A, Schultz SW, Alkhori L, Alenius M.

Cell Rep. 2014 May 8;7(3):672-80. doi: 10.1016/j.celrep.2014.03.052. Epub 2014 Apr 24.

10.

Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation.

Jung B, Padula D, Burtscher I, Landerer C, Lutter D, Theis F, Messias AC, Geerlof A, Sattler M, Kremmer E, Boldt K, Ueffing M, Lickert H.

PLoS One. 2016 Feb 22;11(2):e0149477. doi: 10.1371/journal.pone.0149477. eCollection 2016.

11.

Vertebrate Smoothened functions at the primary cilium.

Corbit KC, Aanstad P, Singla V, Norman AR, Stainier DY, Reiter JF.

Nature. 2005 Oct 13;437(7061):1018-21. Epub 2005 Aug 31.

PMID:
16136078
12.

The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia.

Caparrós-Martín JA, Valencia M, Reytor E, Pacheco M, Fernandez M, Perez-Aytes A, Gean E, Lapunzina P, Peters H, Goodship JA, Ruiz-Perez VL.

Hum Mol Genet. 2013 Jan 1;22(1):124-39. doi: 10.1093/hmg/dds409. Epub 2012 Oct 1.

PMID:
23026747
13.

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved.

Chen MH, Wilson CW, Li YJ, Law KK, Lu CS, Gacayan R, Zhang X, Hui CC, Chuang PT.

Genes Dev. 2009 Aug 15;23(16):1910-28. doi: 10.1101/gad.1794109.

14.

Cilia and developmental signaling.

Eggenschwiler JT, Anderson KV.

Annu Rev Cell Dev Biol. 2007;23:345-73. Review.

15.

Analysis of hedgehog signaling in mouse intraflagellar transport mutants.

Ko HW, Liu A, Eggenschwiler JT.

Methods Cell Biol. 2009;93:347-69. doi: 10.1016/S0091-679X(08)93017-X. Epub 2009 Dec 4.

16.

The contrasting roles of primary cilia and cytonemes in Hh signaling.

Kornberg TB.

Dev Biol. 2014 Oct 1;394(1):1-5. doi: 10.1016/j.ydbio.2014.07.015. Epub 2014 Jul 27.

17.

G-protein-coupled receptors, Hedgehog signaling and primary cilia.

Mukhopadhyay S, Rohatgi R.

Semin Cell Dev Biol. 2014 Sep;33:63-72. doi: 10.1016/j.semcdb.2014.05.002. Epub 2014 May 17. Review.

18.

Hedgehog signaling pathway: a novel model and molecular mechanisms of signal transduction.

Gorojankina T.

Cell Mol Life Sci. 2016 Apr;73(7):1317-32. doi: 10.1007/s00018-015-2127-4. Epub 2016 Jan 13. Review.

PMID:
26762301
19.

Hedgehog signaling from the primary cilium to the nucleus: an emerging picture of ciliary localization, trafficking and transduction.

Nozawa YI, Lin C, Chuang PT.

Curr Opin Genet Dev. 2013 Aug;23(4):429-37. doi: 10.1016/j.gde.2013.04.008. Epub 2013 May 29. Review.

20.

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components.

Qin J, Lin Y, Norman RX, Ko HW, Eggenschwiler JT.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1456-61. doi: 10.1073/pnas.1011410108. Epub 2011 Jan 5.

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