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Items: 1 to 20 of 90

1.

Drug target prediction and prioritization: using orthology to predict essentiality in parasite genomes.

Doyle MA, Gasser RB, Woodcroft BJ, Hall RS, Ralph SA.

BMC Genomics. 2010 Apr 3;11:222. doi: 10.1186/1471-2164-11-222.

2.

SLO-1-channels of parasitic nematodes reconstitute locomotor behaviour and emodepside sensitivity in Caenorhabditis elegans slo-1 loss of function mutants.

Welz C, Krüger N, Schniederjans M, Miltsch SM, Krücken J, Guest M, Holden-Dye L, Harder A, von Samson-Himmelstjerna G.

PLoS Pathog. 2011 Apr;7(4):e1001330. doi: 10.1371/journal.ppat.1001330. Epub 2011 Apr 7.

3.

Exploring transcriptional conservation between Ancylostoma caninum and Haemonchus contortus by oligonucleotide microarray and bioinformatic analyses.

Cantacessi C, Loukas A, Campbell BE, Mulvenna J, Ong EK, Zhong W, Sternberg PW, Otranto D, Gasser RB.

Mol Cell Probes. 2009 Feb;23(1):1-9. doi: 10.1016/j.mcp.2008.09.004. Epub 2008 Oct 11.

PMID:
18977290
4.

Characterization and comparative analysis of the complete Haemonchus contortus β-tubulin gene family and implications for benzimidazole resistance in strongylid nematodes.

Saunders GI, Wasmuth JD, Beech R, Laing R, Hunt M, Naghra H, Cotton JA, Berriman M, Britton C, Gilleard JS.

Int J Parasitol. 2013 May;43(6):465-75. doi: 10.1016/j.ijpara.2012.12.011. Epub 2013 Feb 14.

PMID:
23416426
5.

Atypical (RIO) protein kinases from Haemonchus contortus--promise as new targets for nematocidal drugs.

Campbell BE, Boag PR, Hofmann A, Cantacessi C, Wang CK, Taylor P, Hu M, Sindhu ZU, Loukas A, Sternberg PW, Gasser RB.

Biotechnol Adv. 2011 May-Jun;29(3):338-50. doi: 10.1016/j.biotechadv.2011.01.006. Epub 2011 Jan 22. Review.

PMID:
21262337
6.

Intestinal transcriptomes of nematodes: comparison of the parasites Ascaris suum and Haemonchus contortus with the free-living Caenorhabditis elegans.

Yin Y, Martin J, Abubucker S, Scott AL, McCarter JP, Wilson RK, Jasmer DP, Mitreva M.

PLoS Negl Trop Dis. 2008 Aug 6;2(8):e269. doi: 10.1371/journal.pntd.0000269.

7.

A new enabling proteomics methodology to investigate membrane associated proteins from parasitic nematodes: case study using ivermectin resistant and ivermectin susceptible isolates of Caenorhabditis elegans and Haemonchus contortus.

Hart EH, Brophy PM, Prescott M, Bartley DJ, Wolf BT, Hamilton JV.

Vet Parasitol. 2015 Jan 30;207(3-4):266-75. doi: 10.1016/j.vetpar.2014.12.003. Epub 2014 Dec 15.

PMID:
25537855
8.

Association of ion-channel genotype and macrocyclic lactone sensitivity traits in Haemonchus contortus.

Beech R, Levitt N, Cambos M, Zhou S, Forrester SG.

Mol Biochem Parasitol. 2010 Jun;171(2):74-80. doi: 10.1016/j.molbiopara.2010.02.004. Epub 2010 Mar 6.

PMID:
20211658
9.

Silencing of essential genes by RNA interference in Haemonchus contortus.

Zawadzki JL, Kotze AC, Fritz JA, Johnson NM, Hemsworth JE, Hines BM, Behm CA.

Parasitology. 2012 Apr;139(5):613-29. doi: 10.1017/S0031182012000121. Epub 2012 Feb 20.

PMID:
22348596
10.

Benzimidazole resistance in the ovine Haemonchus contortus from southern Poland - coproscopical and molecular findings.

Kowal J, Wyrobisz A, Nosal P, Kucharski M, Kaczor U, Skalska M, Sendor P.

Ann Parasitol. 2016;62(2):119-23. doi: 10.17420/ap6202.43.

11.

Caenorhabditis elegans ivermectin receptors regulate locomotor behaviour and are functional orthologues of Haemonchus contortus receptors.

Cook A, Aptel N, Portillo V, Siney E, Sihota R, Holden-Dye L, Wolstenholme A.

Mol Biochem Parasitol. 2006 May;147(1):118-25. Epub 2006 Feb 24.

PMID:
16527366
12.

Acetylcholine receptor subunit genes from Ancylostoma caninum: altered transcription patterns associated with pyrantel resistance.

Kopp SR, Coleman GT, Traub RJ, McCarthy JS, Kotze AC.

Int J Parasitol. 2009 Mar;39(4):435-41. doi: 10.1016/j.ijpara.2008.08.005. Epub 2008 Sep 13.

PMID:
18823982
13.

Investigating hookworm genomes by comparative analysis of two Ancylostoma species.

Mitreva M, McCarter JP, Arasu P, Hawdon J, Martin J, Dante M, Wylie T, Xu J, Stajich JE, Kapulkin W, Clifton SW, Waterston RH, Wilson RK.

BMC Genomics. 2005 Apr 26;6:58.

14.

Genetic evidence for hybridisation between Haemonchus contortus and Haemonchus placei in natural field populations and its implications for interspecies transmission of anthelmintic resistance.

Chaudhry U, Redman EM, Abbas M, Muthusamy R, Ashraf K, Gilleard JS.

Int J Parasitol. 2015 Feb;45(2-3):149-59. doi: 10.1016/j.ijpara.2014.09.002. Epub 2014 Nov 4.

PMID:
25449043
15.

Genetic analysis of a relationship between macrocyclic lactone and benzimidazole anthelmintic selection on Haemonchus contortus.

de Lourdes Mottier M, Prichard RK.

Pharmacogenet Genomics. 2008 Feb;18(2):129-40. doi: 10.1097/FPC.0b013e3282f4711d.

PMID:
18192899
16.

The cytochrome P450 family in the parasitic nematode Haemonchus contortus.

Laing R, Bartley DJ, Morrison AA, Rezansoff A, Martinelli A, Laing ST, Gilleard JS.

Int J Parasitol. 2015 Mar;45(4):243-51. doi: 10.1016/j.ijpara.2014.12.001. Epub 2014 Dec 31.

17.

Haemonchus contortus as a paradigm and model to study anthelmintic drug resistance.

Gilleard JS.

Parasitology. 2013 Oct;140(12):1506-22. doi: 10.1017/S0031182013001145. Review.

PMID:
23998513
18.

Resistance as a tool for discovering and understanding targets in parasite neuromusculature.

Sangster NC, Song J, Demeler J.

Parasitology. 2005;131 Suppl:S179-90. Review.

PMID:
16569289
19.

Nicotinic acetylcholine receptors: a comparison of the nAChRs of Caenorhabditis elegans and parasitic nematodes.

Holden-Dye L, Joyner M, O'Connor V, Walker RJ.

Parasitol Int. 2013 Dec;62(6):606-15. doi: 10.1016/j.parint.2013.03.004. Epub 2013 Mar 15. Review.

PMID:
23500392
20.

Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus.

Lecová L, Růžičková M, Laing R, Vogel H, Szotáková B, Prchal L, Lamka J, Vokřál I, Skálová L, Matoušková P.

Mol Biochem Parasitol. 2015 Jun;201(2):123-7. doi: 10.1016/j.molbiopara.2015.08.001. Epub 2015 Aug 6.

PMID:
26255779

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