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Items: 1 to 20 of 115

1.

Cell-type-specific long-range looping interactions identify distant regulatory elements of the CFTR gene.

Gheldof N, Smith EM, Tabuchi TM, Koch CM, Dunham I, Stamatoyannopoulos JA, Dekker J.

Nucleic Acids Res. 2010 Jul;38(13):4325-36. doi: 10.1093/nar/gkq175. Epub 2010 Mar 31.

2.

Analysis of long-range interactions in primary human cells identifies cooperative CFTR regulatory elements.

Moisan S, Berlivet S, Ka C, Le Gac G, Dostie J, Férec C.

Nucleic Acids Res. 2016 Apr 7;44(6):2564-76. doi: 10.1093/nar/gkv1300. Epub 2015 Nov 28.

3.

Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus.

Ott CJ, Blackledge NP, Kerschner JL, Leir SH, Crawford GE, Cotton CU, Harris A.

Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19934-9. doi: 10.1073/pnas.0900946106. Epub 2009 Nov 6.

4.

Genomic approaches for the discovery of CFTR regulatory elements.

Ott CJ, Harris A.

Transcription. 2011 Jan-Feb;2(1):23-7. doi: 10.4161/trns.2.1.13693.

5.

A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter.

Ott CJ, Suszko M, Blackledge NP, Wright JE, Crawford GE, Harris A.

J Cell Mol Med. 2009 Apr;13(4):680-92.

6.

Molecular mechanisms controlling CFTR gene expression in the airway.

Zhang Z, Ott CJ, Lewandowska MA, Leir SH, Harris A.

J Cell Mol Med. 2012 Jun;16(6):1321-30. doi: 10.1111/j.1582-4934.2011.01439.x.

7.

Invariant TAD Boundaries Constrain Cell-Type-Specific Looping Interactions between Promoters and Distal Elements around the CFTR Locus.

Smith EM, Lajoie BR, Jain G, Dekker J.

Am J Hum Genet. 2016 Jan 7;98(1):185-201. doi: 10.1016/j.ajhg.2015.12.002.

8.

Cross-species characterization of the promoter region of the cystic fibrosis transmembrane conductance regulator gene reveals multiple levels of regulation.

Vuillaumier S, Dixmeras I, Messaï H, Lapouméroulie C, Lallemand D, Gekas J, Chehab FF, Perret C, Elion J, Denamur E.

Biochem J. 1997 Nov 1;327 ( Pt 3):651-62.

9.

Transcriptional regulation of CFTR gene expression.

Gillen AE, Harris A.

Front Biosci (Elite Ed). 2012 Jan 1;4:587-92. Review.

PMID:
22201896
10.

Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus.

Yang R, Kerschner JL, Gosalia N, Neems D, Gorsic LK, Safi A, Crawford GE, Kosak ST, Leir SH, Harris A.

Nucleic Acids Res. 2016 Apr 20;44(7):3082-94. doi: 10.1093/nar/gkv1358. Epub 2015 Dec 15.

11.

Novel regulatory mechanisms for the CFTR gene.

Ott CJ, Blackledge NP, Leir SH, Harris A.

Biochem Soc Trans. 2009 Aug;37(Pt 4):843-8. doi: 10.1042/BST0370843. Review.

12.

DNA polymorphisms in potential regulatory elements of the CFTR gene alter transcription factor binding.

Rowntree R, Harris A.

Hum Genet. 2002 Jul;111(1):66-74. Epub 2002 Jun 6.

PMID:
12136238
13.

An insulator element 3' to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells.

Blackledge NP, Ott CJ, Gillen AE, Harris A.

Nucleic Acids Res. 2009 Mar;37(4):1086-94. doi: 10.1093/nar/gkn1056. Epub 2009 Jan 7.

14.

In vivo analysis of DNase I hypersensitive sites in the human CFTR gene.

Moulin DS, Manson AL, Nuthall HN, Smith DJ, Huxley C, Harris A.

Mol Med. 1999 Apr;5(4):211-23.

15.

Multiple potential intragenic regulatory elements in the CFTR gene.

Smith DJ, Nuthall HN, Majetti ME, Harris A.

Genomics. 2000 Feb 15;64(1):90-6.

PMID:
10708521
16.
17.

CTCF mediates insulator function at the CFTR locus.

Blackledge NP, Carter EJ, Evans JR, Lawson V, Rowntree RK, Harris A.

Biochem J. 2007 Dec 1;408(2):267-75.

18.

CHD6 regulates the topological arrangement of the CFTR locus.

Sancho A, Li S, Paul T, Zhang F, Aguilo F, Vashisht A, Balasubramaniyan N, Leleiko NS, Suchy FJ, Wohlschlegel JA, Zhang W, Walsh MJ.

Hum Mol Genet. 2015 May 15;24(10):2724-32. doi: 10.1093/hmg/ddv032. Epub 2015 Jan 28.

19.

A regulatory element in intron 1 of the cystic fibrosis transmembrane conductance regulator gene.

Smith AN, Barth ML, McDowell TL, Moulin DS, Nuthall HN, Hollingsworth MA, Harris A.

J Biol Chem. 1996 Apr 26;271(17):9947-54.

20.

Analysis of a DNase I hypersensitive site located -20.9 kb upstream of the CFTR gene.

Nuthall HN, Vassaux G, Huxley C, Harris A.

Eur J Biochem. 1999 Dec;266(2):431-43.

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