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Items: 1 to 20 of 115

1.

Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA.

Mitchell M, Gillis A, Futahashi M, Fujiwara H, Skordalakes E.

Nat Struct Mol Biol. 2010 Apr;17(4):513-8. doi: 10.1038/nsmb.1777. Epub 2010 Mar 28.

PMID:
20357774
2.

Structure of the Tribolium castaneum telomerase catalytic subunit TERT.

Gillis AJ, Schuller AP, Skordalakes E.

Nature. 2008 Oct 2;455(7213):633-7. doi: 10.1038/nature07283. Epub 2008 Aug 31.

PMID:
18758444
3.

Crystallographic Studies of Telomerase.

Hoffman H, Skordalakes E.

Methods Enzymol. 2016;573:403-19. doi: 10.1016/bs.mie.2016.04.006. Epub 2016 May 10.

4.

Human telomerase specialization for repeat synthesis by unique handling of primer-template duplex.

Wu RA, Collins K.

EMBO J. 2014 Apr 16;33(8):921-35. doi: 10.1002/embj.201387205. Epub 2014 Mar 11.

5.

Structural basis of template-boundary definition in Tetrahymena telomerase.

Jansson LI, Akiyama BM, Ooms A, Lu C, Rubin SM, Stone MD.

Nat Struct Mol Biol. 2015 Nov;22(11):883-8. doi: 10.1038/nsmb.3101. Epub 2015 Oct 5.

6.

The telomerase essential N-terminal domain promotes DNA synthesis by stabilizing short RNA-DNA hybrids.

Akiyama BM, Parks JW, Stone MD.

Nucleic Acids Res. 2015 Jun 23;43(11):5537-49. doi: 10.1093/nar/gkv406. Epub 2015 May 4.

7.

A conserved motif in Tetrahymena thermophila telomerase reverse transcriptase is proximal to the RNA template and is essential for boundary definition.

Akiyama BM, Gomez A, Stone MD.

J Biol Chem. 2013 Jul 26;288(30):22141-9. doi: 10.1074/jbc.M113.452425. Epub 2013 Jun 11.

8.

In vitro reconstitution of the active T. castaneum telomerase.

Schuller AP, Harkisheimer MJ, Skordalakes E.

J Vis Exp. 2011 Jul 14;(53):e2799. doi: 10.3791/2799.

9.

Human telomerase model shows the role of the TEN domain in advancing the double helix for the next polymerization step.

Steczkiewicz K, Zimmermann MT, Kurcinski M, Lewis BA, Dobbs D, Kloczkowski A, Jernigan RL, Kolinski A, Ginalski K.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9443-8. doi: 10.1073/pnas.1015399108. Epub 2011 May 23.

10.

RNA binding domain of telomerase reverse transcriptase.

Lai CK, Mitchell JR, Collins K.

Mol Cell Biol. 2001 Feb;21(4):990-1000.

11.

The structure of an enzyme-activating fragment of human telomerase RNA.

Leeper TC, Varani G.

RNA. 2005 Apr;11(4):394-403. Epub 2005 Feb 9.

12.

Human telomerase contains two cooperating telomerase RNA molecules.

Wenz C, Enenkel B, Amacker M, Kelleher C, Damm K, Lingner J.

EMBO J. 2001 Jul 2;20(13):3526-34.

13.

Evolutionary perspectives of telomerase RNA structure and function.

Podlevsky JD, Chen JJ.

RNA Biol. 2016 Aug 2;13(8):720-32. doi: 10.1080/15476286.2016.1205768. Epub 2016 Jun 30. Review.

14.

A mutation in the catalytic subunit of yeast telomerase alters primer-template alignment while promoting processivity and protein-DNA binding.

Bairley RC, Guillaume G, Vega LR, Friedman KL.

J Cell Sci. 2011 Dec 15;124(Pt 24):4241-52. doi: 10.1242/jcs.090761. Epub 2011 Dec 22.

15.

Telomerase as a DNA-dependent DNA polymerase.

Legassie JD, Jarstfer MB.

Biochemistry. 2005 Nov 1;44(43):14191-201.

PMID:
16245935
16.

A physical and functional constituent of telomerase anchor site.

Lue NF.

J Biol Chem. 2005 Jul 15;280(28):26586-91. Epub 2005 May 18.

17.

Insights into diseases of human telomerase from dynamical modeling.

Flores SC, Zemora G, Waldsich C.

Pac Symp Biocomput. 2013:200-11.

18.

Direct involvement of the TEN domain at the active site of human telomerase.

Jurczyluk J, Nouwens AS, Holien JK, Adams TE, Lovrecz GO, Parker MW, Cohen SB, Bryan TM.

Nucleic Acids Res. 2011 Mar;39(5):1774-88. doi: 10.1093/nar/gkq1083. Epub 2010 Nov 3.

19.

Template boundary definition in Tetrahymena telomerase.

Lai CK, Miller MC, Collins K.

Genes Dev. 2002 Feb 15;16(4):415-20.

20.

Telomerase RNA is more than a DNA template.

Webb CJ, Zakian VA.

RNA Biol. 2016 Aug 2;13(8):683-9. doi: 10.1080/15476286.2016.1191725. Epub 2016 May 31. Review.

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