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Items: 1 to 20 of 111

1.

Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights.

Goto Y, Li B, Claesen J, Shi Y, Bibb MJ, van der Donk WA.

PLoS Biol. 2010 Mar 23;8(3):e1000339. doi: 10.1371/journal.pbio.1000339.

2.

Insights into the evolution of lanthipeptide biosynthesis.

Yu Y, Zhang Q, van der Donk WA.

Protein Sci. 2013 Nov;22(11):1478-89. doi: 10.1002/pro.2358. Epub 2013 Sep 18. Review.

3.

Curvopeptin: a new lanthionine-containing class III lantibiotic and its co-substrate promiscuous synthetase.

Krawczyk B, Völler GH, Völler J, Ensle P, Süssmuth RD.

Chembiochem. 2012 Sep 24;13(14):2065-71. doi: 10.1002/cbic.201200417. Epub 2012 Aug 20.

PMID:
22907786
4.

Characterization of new class III lantibiotics--erythreapeptin, avermipeptin and griseopeptin from Saccharopolyspora erythraea, Streptomyces avermitilis and Streptomyces griseus demonstrates stepwise N-terminal leader processing.

Völler GH, Krawczyk JM, Pesic A, Krawczyk B, Nachtigall J, Süssmuth RD.

Chembiochem. 2012 May 29;13(8):1174-83. doi: 10.1002/cbic.201200118. Epub 2012 May 3.

PMID:
22556031
5.

Mechanistic studies of Ser/Thr dehydration catalyzed by a member of the LanL lanthionine synthetase family.

Goto Y, Okesli A, van der Donk WA.

Biochemistry. 2011 Feb 8;50(5):891-8. doi: 10.1021/bi101750r. Epub 2011 Jan 13.

6.

In vitro catalytic activity of N-terminal and C-terminal domains in NukM, the post-translational modification enzyme of nukacin ISK-1.

Shimafuji C, Noguchi M, Nishie M, Nagao J, Shioya K, Zendo T, Nakayama J, Sonomoto K.

J Biosci Bioeng. 2015 Dec;120(6):624-9. doi: 10.1016/j.jbiosc.2015.03.020. Epub 2015 May 9.

PMID:
25971839
7.

Using expressed protein ligation to probe the substrate specificity of lantibiotic synthetases.

Zhang X, van der Donk WA.

Methods Enzymol. 2009;462:117-34. doi: 10.1016/S0076-6879(09)62006-1.

PMID:
19632472
8.

Genome-wide search for eliminylating domains reveals novel function for BLES03-like proteins.

Khater S, Mohanty D.

Genome Biol Evol. 2014 Jul 24;6(8):2017-33. doi: 10.1093/gbe/evu161.

9.

Chapter 21. In vitro studies of lantibiotic biosynthesis.

Li B, Cooper LE, van der Donk WA.

Methods Enzymol. 2009;458:533-58. doi: 10.1016/S0076-6879(09)04821-6.

PMID:
19374997
10.

Evolution of lanthipeptide synthetases.

Zhang Q, Yu Y, Vélasquez JE, van der Donk WA.

Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18361-6. doi: 10.1073/pnas.1210393109. Epub 2012 Oct 15.

11.

Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic.

McClerren AL, Cooper LE, Quan C, Thomas PM, Kelleher NL, van der Donk WA.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17243-8. Epub 2006 Nov 3.

12.

Michael-type cyclizations in lantibiotic biosynthesis are reversible.

Yang X, van der Donk WA.

ACS Chem Biol. 2015 May 15;10(5):1234-8. doi: 10.1021/acschembio.5b00007. Epub 2015 Mar 10.

13.

Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity.

Martin NI, Sprules T, Carpenter MR, Cotter PD, Hill C, Ross RP, Vederas JC.

Biochemistry. 2004 Mar 23;43(11):3049-56.

PMID:
15023056
14.

Engineering dehydro amino acids and thioethers into peptides using lacticin 481 synthetase.

Chatterjee C, Patton GC, Cooper L, Paul M, van der Donk WA.

Chem Biol. 2006 Oct;13(10):1109-17.

15.

Distributive and directional behavior of lantibiotic synthetases revealed by high-resolution tandem mass spectrometry.

Lee MV, Ihnken LA, You YO, McClerren AL, van der Donk WA, Kelleher NL.

J Am Chem Soc. 2009 Sep 2;131(34):12258-64. doi: 10.1021/ja9033507.

16.

Lanthionine introduction into nukacin ISK-1 prepeptide by co-expression with modification enzyme NukM in Escherichia coli.

Nagao J, Harada Y, Shioya K, Aso Y, Zendo T, Nakayama J, Sonomoto K.

Biochem Biophys Res Commun. 2005 Oct 21;336(2):507-13.

PMID:
16143300
17.

Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production.

Chatterjee C, Miller LM, Leung YL, Xie L, Yi M, Kelleher NL, van der Donk WA.

J Am Chem Soc. 2005 Nov 9;127(44):15332-3.

PMID:
16262372
18.

Investigation of the substrate specificity of lacticin 481 synthetase by using nonproteinogenic amino acids.

Levengood MR, Kerwood CC, Chatterjee C, van der Donk WA.

Chembiochem. 2009 Mar 23;10(5):911-9. doi: 10.1002/cbic.200800752.

19.

Lantibiotics: peptides of diverse structure and function.

Willey JM, van der Donk WA.

Annu Rev Microbiol. 2007;61:477-501. Review.

PMID:
17506681
20.

Effect of bioengineering lacticin 3147 lanthionine bridges on specific activity and resistance to heat and proteases.

Suda S, Westerbeek A, O'Connor PM, Ross RP, Hill C, Cotter PD.

Chem Biol. 2010 Oct 29;17(10):1151-60. doi: 10.1016/j.chembiol.2010.08.011.

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