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Items: 1 to 20 of 277

1.

The absence of functional PI3Kgamma prevents leukocyte recruitment and ameliorates DSS-induced colitis in mice.

van Dop WA, Marengo S, te Velde AA, Ciraolo E, Franco I, ten Kate FJ, Boeckxstaens GE, Hardwick JC, Hommes DW, Hirsch E, van den Brink GR.

Immunol Lett. 2010 Jun 15;131(1):33-9. doi: 10.1016/j.imlet.2010.03.008. Epub 2010 Mar 27.

PMID:
20347874
2.

Inhibition of phosphoinositide 3-kinase ameliorates dextran sodium sulfate-induced colitis in mice.

Peng XD, Wu XH, Chen LJ, Wang ZL, Hu XH, Song LF, He CM, Luo YF, Chen ZZ, Jin K, Lin HG, Li XL, Wang YS, Wei YQ.

J Pharmacol Exp Ther. 2010 Jan;332(1):46-56. doi: 10.1124/jpet.109.153494. Epub 2009 Oct 14.

3.

Blockade of CXCL12/CXCR4 axis ameliorates murine experimental colitis.

Mikami S, Nakase H, Yamamoto S, Takeda Y, Yoshino T, Kasahara K, Ueno S, Uza N, Oishi S, Fujii N, Nagasawa T, Chiba T.

J Pharmacol Exp Ther. 2008 Nov;327(2):383-92. doi: 10.1124/jpet.108.141085. Epub 2008 Aug 20.

4.

In vivo treatment with a nonapeptide thymic hormone, facteur thymique serique (FTS), ameliorates chronic colitis induced by dextran sulphate sodium in mice.

Sun X, Yamada H, Yoshihara K, Awaya A, Yoshikai Y.

Int Immunopharmacol. 2007 Jul;7(7):928-36. Epub 2007 Mar 28.

PMID:
17499195
5.

CD40-CD40 ligand mediates the recruitment of leukocytes and platelets in the inflamed murine colon.

Vowinkel T, Anthoni C, Wood KC, Stokes KY, Russell J, Gray L, Bharwani S, Senninger N, Alexander JS, Krieglstein CF, Grisham MB, Granger DN.

Gastroenterology. 2007 Mar;132(3):955-65. Epub 2006 Dec 17.

PMID:
17324402
6.

Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-gamma and TNF-alpha production.

Siegmund B, Fantuzzi G, Rieder F, Gamboni-Robertson F, Lehr HA, Hartmann G, Dinarello CA, Endres S, Eigler A.

Am J Physiol Regul Integr Comp Physiol. 2001 Oct;281(4):R1264-73.

7.

The simultaneous blockade of chemokine receptors CCR2, CCR5 and CXCR3 by a non-peptide chemokine receptor antagonist protects mice from dextran sodium sulfate-mediated colitis.

Tokuyama H, Ueha S, Kurachi M, Matsushima K, Moriyasu F, Blumberg RS, Kakimi K.

Int Immunol. 2005 Aug;17(8):1023-34. Epub 2005 Jul 6.

PMID:
16000328
8.

G protein-coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate-induced colitis in mice.

Eijkelkamp N, Heijnen CJ, Lucas A, Premont RT, Elsenbruch S, Schedlowski M, Kavelaars A.

Gut. 2007 Jun;56(6):847-54. Epub 2007 Jan 17.

9.

P-selectin glycoprotein ligand-1 modulates immune inflammatory responses in the enteric lamina propria.

Nuñez-Andrade N, Lamana A, Sancho D, Gisbert JP, Gonzalez-Amaro R, Sanchez-Madrid F, Urzainqui A.

J Pathol. 2011 Jun;224(2):212-21. doi: 10.1002/path.2850. Epub 2011 Mar 22.

PMID:
21432853
10.
11.

Inducible nitric oxide synthase from bone marrow-derived cells plays a critical role in regulating colonic inflammation.

Beck PL, Li Y, Wong J, Chen CW, Keenan CM, Sharkey KA, McCafferty DM.

Gastroenterology. 2007 May;132(5):1778-90. Epub 2007 Jan 25.

PMID:
17449036
12.

Loss of phosphoinositide 3-kinase P110γ is protective in the acute phase but detrimental in the resolution phase of hapten-induced colitis.

Prescott D, Atkinson B, Döring A, Brown S, Petri B, McKay DM, Waterhouse CC.

Inflamm Bowel Dis. 2013 Mar;19(3):489-500. doi: 10.1097/MIB.0b013e31827feb84.

PMID:
23282580
13.

Phosphatidylinositol 3-kinase gamma inhibition ameliorates inflammation and tumor growth in a model of colitis-associated cancer.

González-García A, Sánchez-Ruiz J, Flores JM, Carrera AC.

Gastroenterology. 2010 Apr;138(4):1374-83. doi: 10.1053/j.gastro.2009.12.001. Epub 2009 Dec 11.

PMID:
20004201
14.

Aggravation of intestinal inflammation by depletion/deficiency of gammadelta T cells in different types of IBD animal models.

Kühl AA, Pawlowski NN, Grollich K, Loddenkemper C, Zeitz M, Hoffmann JC.

J Leukoc Biol. 2007 Jan;81(1):168-75. Epub 2006 Oct 13.

PMID:
17041003
15.

The role of the complement and contact systems in the dextran sulfate sodium-induced colitis model: the effect of C1 inhibitor in inflammatory bowel disease.

Lu F, Fernandes SM, Davis AE 3rd.

Am J Physiol Gastrointest Liver Physiol. 2010 Jun;298(6):G878-83. doi: 10.1152/ajpgi.00400.2009. Epub 2010 Mar 25.

16.

PECAM-1 (CD 31) mediates transendothelial leukocyte migration in experimental colitis.

Rijcken E, Mennigen RB, Schaefer SD, Laukoetter MG, Anthoni C, Spiegel HU, Bruewer M, Senninger N, Krieglstein CF.

Am J Physiol Gastrointest Liver Physiol. 2007 Aug;293(2):G446-52. Epub 2007 May 17.

17.

Amelioration of dextran sulfate sodium-induced colitis by anti-macrophage migration inhibitory factor antibody in mice.

Ohkawara T, Nishihira J, Takeda H, Hige S, Kato M, Sugiyama T, Iwanaga T, Nakamura H, Mizue Y, Asaka M.

Gastroenterology. 2002 Jul;123(1):256-70.

PMID:
12105854
18.

Inhibition of selectin function and leukocyte rolling protects against dextran sodium sulfate-induced murine colitis.

Zhang XW, Liu Q, Thorlacius H.

Scand J Gastroenterol. 2001 Mar;36(3):270-5.

PMID:
11305514
19.

A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis.

Ungaro R, Fukata M, Hsu D, Hernandez Y, Breglio K, Chen A, Xu R, Sotolongo J, Espana C, Zaias J, Elson G, Mayer L, Kosco-Vilbois M, Abreu MT.

Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1167-79. doi: 10.1152/ajpgi.90496.2008. Epub 2009 Apr 9.

20.

Phosphoinositide 3-kinase γ plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice.

Russo RC, Garcia CC, Barcelos LS, Rachid MA, Guabiraba R, Roffê E, Souza AL, Sousa LP, Mirolo M, Doni A, Cassali GD, Pinho V, Locati M, Teixeira MM.

J Leukoc Biol. 2011 Feb;89(2):269-82. doi: 10.1189/jlb.0610346. Epub 2010 Nov 2.

PMID:
21048214

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