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Items: 1 to 20 of 132

1.

The role of ThPOK in control of CD4/CD8 lineage commitment.

He X, Park K, Kappes DJ.

Annu Rev Immunol. 2010;28:295-320. doi: 10.1146/annurev.immunol.25.022106.141715. Review.

PMID:
20307210
2.

CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus.

He X, Park K, Wang H, He X, Zhang Y, Hua X, Li Y, Kappes DJ.

Immunity. 2008 Mar;28(3):346-58. doi: 10.1016/j.immuni.2008.02.006.

3.

Role of the transcription factor Th-POK in CD4:CD8 lineage commitment.

Kappes DJ, He X, He X.

Immunol Rev. 2006 Feb;209:237-52. Review.

PMID:
16448546
4.

Transcriptional and epigenetic regulation of CD4/CD8 lineage choice.

Taniuchi I, Ellmeier W.

Adv Immunol. 2011;110:71-110. doi: 10.1016/B978-0-12-387663-8.00003-X. Review.

PMID:
21762816
5.

CD4-CD8 lineage differentiation: Thpok-ing into the nucleus.

Wang L, Bosselut R.

J Immunol. 2009 Sep 1;183(5):2903-10. doi: 10.4049/jimmunol.0901041. Review.

7.

The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment.

He X, He X, Dave VP, Zhang Y, Hua X, Nicolas E, Xu W, Roe BA, Kappes DJ.

Nature. 2005 Feb 24;433(7028):826-33.

8.

The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate.

Yasutomo K, Doyle C, Miele L, Fuchs C, Germain RN.

Nature. 2000 Mar 30;404(6777):506-10. Erratum in: Nature 2000 Sep 7;407(6800):110.

PMID:
10761920
9.

Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells.

Wang L, Wildt KF, Zhu J, Zhang X, Feigenbaum L, Tessarollo L, Paul WE, Fowlkes BJ, Bosselut R.

Nat Immunol. 2008 Oct;9(10):1122-30. doi: 10.1038/ni.1647. Epub 2008 Sep 7.

10.

TCR and Notch signaling in CD4 and CD8 T-cell development.

Laky K, Fleischacker C, Fowlkes BJ.

Immunol Rev. 2006 Feb;209:274-83. Review.

PMID:
16448548
11.

Gene expression profiling in mice with enforced Gata3 expression reveals putative targets of Gata3 in double positive thymocytes.

van Hamburg JP, de Bruijn MJ, Ribeiro de Almeida C, Dingjan GM, Hendriks RW.

Mol Immunol. 2009 Oct;46(16):3251-60. doi: 10.1016/j.molimm.2009.08.004. Epub 2009 Sep 2.

PMID:
19729201
12.

Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice.

Singer A, Adoro S, Park JH.

Nat Rev Immunol. 2008 Oct;8(10):788-801. doi: 10.1038/nri2416. Review.

13.

CD4/CD8 lineage commitment: light at the end of the tunnel?

He X, Kappes DJ.

Curr Opin Immunol. 2006 Apr;18(2):135-42. Epub 2006 Feb 15. Review.

PMID:
16480861
14.

CCR7 expression in developing thymocytes is linked to the CD4 versus CD8 lineage decision.

Yin X, Ladi E, Chan SW, Li O, Killeen N, Kappes DJ, Robey EA.

J Immunol. 2007 Dec 1;179(11):7358-64.

15.

Antagonistic interplay between ThPOK and Runx in lineage choice of thymocytes.

Egawa T, Taniuchi I.

Blood Cells Mol Dis. 2009 Jul-Aug;43(1):27-9. doi: 10.1016/j.bcmd.2009.03.004. Epub 2009 Apr 16.

PMID:
19375362
16.

The enigma of CD4-lineage specification.

Xiong Y, Bosselut R.

Eur J Immunol. 2011 Mar;41(3):568-74. doi: 10.1002/eji.201041098. Epub 2011 Feb 10. Review.

17.

MAZR and Runx Factors Synergistically Repress ThPOK during CD8+ T Cell Lineage Development.

Sakaguchi S, Hainberger D, Tizian C, Tanaka H, Okuda T, Taniuchi I, Ellmeier W.

J Immunol. 2015 Sep 15;195(6):2879-87. doi: 10.4049/jimmunol.1500387. Epub 2015 Aug 7.

18.

Molecular control of CD4(+) T cell lineage plasticity and integrity.

Ellmeier W.

Int Immunopharmacol. 2015 Oct;28(2):813-7. doi: 10.1016/j.intimp.2015.03.050. Epub 2015 Apr 9. Review.

PMID:
25864621
19.
20.

Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model.

Erman B, Alag AS, Dahle O, van Laethem F, Sarafova SD, Guinter TI, Sharrow SO, Grinberg A, Love PE, Singer A.

J Immunol. 2006 Nov 15;177(10):6613-25.

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