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Items: 1 to 20 of 84

1.

Cysteine reversal of the novel neuromuscular blocking drug CW002 in dogs: pharmacodynamics, acute cardiovascular effects, and preliminary toxicology.

Sunaga H, Malhotra JK, Yoon E, Savarese JJ, Heerdt PM.

Anesthesiology. 2010 Apr;112(4):900-9. doi: 10.1097/ALN.0b013e3181d31f8c.

PMID:
20234310
2.

Pharmacodynamics and cardiopulmonary side effects of CW002, a cysteine-reversible neuromuscular blocking drug in dogs.

Heerdt PM, Malhotra JK, Pan BY, Sunaga H, Savarese JJ.

Anesthesiology. 2010 Apr;112(4):910-6. doi: 10.1097/ALN.0b013e3181d31f71.

PMID:
20234311
3.

Comparative pharmacodynamics of pancuronium, cisatracurium, and CW002 in rabbits.

Diaz LL, Zhang J, Heerdt PM.

J Am Assoc Lab Anim Sci. 2014 May;53(3):283-9.

4.

Dose-response and Cardiopulmonary Side Effects of the Novel Neuromuscular-blocking Drug CW002 in Man.

Heerdt PM, Sunaga H, Owen JS, Murrell MT, Malhotra JK, Godfrey D, Steinkamp M, Savard P, Savarese JJ, Lien CA.

Anesthesiology. 2016 Dec;125(6):1136-1143.

PMID:
27749289
5.
6.

Mivacurium chloride (BW B1090U)-induced neuromuscular blockade during nitrous oxide-isoflurane and nitrous oxide-narcotic anesthesia in adult surgical patients.

Weber S, Brandom BW, Powers DM, Sarner JB, Woelfel SK, Cook DR, Foster VJ, McNulty BF, Weakly JN.

Anesth Analg. 1988 Jun;67(6):495-9.

PMID:
2967644
7.

Pharmacodynamic and hemodynamic effects of mivacurium in infants anesthetized with halothane and nitrous oxide.

Goudsouzian NG, Denman W, Schwartz A, Shorten G, Foster V, Samara B.

Anesthesiology. 1993 Nov;79(5):919-25.

PMID:
8239009
8.

Preclinical Pharmacology of CW002: A Nondepolarizing Neuromuscular Blocking Drug of Intermediate Duration, Degraded and Antagonized by l-cysteine-Additional Studies of Safety and Efficacy in the Anesthetized Rhesus Monkey and Cat.

Sunaga H, Savarese JJ, McGilvra JD, Heerdt PM, Belmont MR, Van Ornum SG, Murrell MT, Malhotra JK, Savard PM, Jeannotte E, Petty BJ, Allen E, Carnathan GW.

Anesthesiology. 2016 Oct;125(4):732-743.

PMID:
27466033
9.

Neuromuscular blocking action of atracurium in the dog and its reversal by neostigmine.

Jones RS, Hunter JM, Utting JE.

Res Vet Sci. 1983 Mar;34(2):173-6.

PMID:
6687951
10.

Effects of cisatracurium in children during halothane-nitrous oxide anesthesia.

Brandom BW, Woelfel SK, Ference A, Dayal B, Cook DR, Kerls S.

J Clin Anesth. 1998 May;10(3):195-9.

PMID:
9603588
11.

Rapid chemical antagonism of neuromuscular blockade by L-cysteine adduction to and inactivation of the olefinic (double-bonded) isoquinolinium diester compounds gantacurium (AV430A), CW 002, and CW 011.

Savarese JJ, McGilvra JD, Sunaga H, Belmont MR, Van Ornum SG, Savard PM, Heerdt PM.

Anesthesiology. 2010 Jul;113(1):58-73. doi: 10.1097/ALN.0b013e3181dc1b5b.

PMID:
20526187
12.

The cardiovascular effects and histamine-releasing properties of 51W89 in patients receiving nitrous oxide/opioid/barbiturate anesthesia.

Lien CA, Belmont MR, Abalos A, Eppich L, Quessy S, Abou-Donia MM, Savarese JJ.

Anesthesiology. 1995 May;82(5):1131-8.

PMID:
7537945
13.

Dose-related cardiovascular effects of amrinone and epinephrine in reversing bupivacaine-induced cardiovascular depression.

Igarashi T, Hirabayashi Y, Saitoh K, Fukuda H, Shimizu R, Mitsuhata H.

Acta Anaesthesiol Scand. 1998 Jul;42(6):698-706.

PMID:
9689277
14.

[Neuromuscular and cardiovascular effect of mivacurium in anesthesia induction in patients with renal failure].

Blobner M, Jelen-Esselborn S, Mann R, Kling M, Schneider G, Schneck HJ, Kochs E.

Anasthesiol Intensivmed Notfallmed Schmerzther. 1996 Feb;31(1):15-21. German.

PMID:
8868527
15.

Enzymatic antagonism of mivacurium-induced neuromuscular blockade by human plasma cholinesterase.

Naguib M, Daoud W, el-Gammal M, Ammar A, Turkistani A, Selim M, Altamimi W, Sohaibani MO.

Anesthesiology. 1995 Oct;83(4):694-701.

PMID:
7574048
16.

Cardiovascular and neuromuscular effects of Org NC 45, pancuronium, metocurine, and d-tubocurarine in dogs.

Booij LH, Edwards RP, Sohn YJ, Miller RD.

Anesth Analg. 1980 Jan;59(1):26-30.

PMID:
7188662
17.

The neuromuscular blocking and cardiovascular effects of doxacurium chloride in patients receiving nitrous oxide narcotic anesthesia.

Murray DJ, Mehta MP, Choi WW, Forbes RB, Sokoll MD, Gergis SD, Rudd GD, Abou-Donia MM.

Anesthesiology. 1988 Oct;69(4):472-7.

PMID:
3177909
18.

Antagonism of mivacurium-induced neuromuscular blockade in humans. Edrophonium dose requirements at threshold train-of-four count of 4.

Kopman AF, Mallhi MU, Justo MD, Rodricks P, Neuman GG.

Anesthesiology. 1994 Dec;81(6):1394-400.

PMID:
7992908
19.

NTP Toxicology and Carcinogenesis Studies of Coumarin (CAS No. 91-64-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies).

National Toxicology Program .

Natl Toxicol Program Tech Rep Ser. 1993 Sep;422:1-340.

20.

Cardiovascular and neuromuscular effects of three steroidal neuromuscular blocking drugs in dogs (ORG 9616, ORG 9426, ORG 9991).

Cason B, Baker DG, Hickey RF, Miller RD, Agoston S.

Anesth Analg. 1990 Apr;70(4):382-8.

PMID:
1969251

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