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Items: 1 to 20 of 104

1.

Regulation of bile acid synthesis by fat-soluble vitamins A and D.

Schmidt DR, Holmstrom SR, Fon Tacer K, Bookout AL, Kliewer SA, Mangelsdorf DJ.

J Biol Chem. 2010 May 7;285(19):14486-94. doi: 10.1074/jbc.M110.116004. Epub 2010 Mar 16.

2.

Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol.

Chow EC, Magomedova L, Quach HP, Patel R, Durk MR, Fan J, Maeng HJ, Irondi K, Anakk S, Moore DD, Cummins CL, Pang KS.

Gastroenterology. 2014 Apr;146(4):1048-59. doi: 10.1053/j.gastro.2013.12.027. Epub 2013 Dec 21.

PMID:
24365583
3.

Intestinal FXR-mediated FGF15 production contributes to diurnal control of hepatic bile acid synthesis in mice.

Stroeve JH, Brufau G, Stellaard F, Gonzalez FJ, Staels B, Kuipers F.

Lab Invest. 2010 Oct;90(10):1457-67. doi: 10.1038/labinvest.2010.107. Epub 2010 Jun 7.

4.

Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle.

De Fabiani E, Mitro N, Gilardi F, Caruso D, Galli G, Crestani M.

J Biol Chem. 2003 Oct 3;278(40):39124-32. Epub 2003 Jul 15.

5.

Inhibition of ileal apical but not basolateral bile acid transport reduces atherosclerosis in apoE⁻/⁻ mice.

Lan T, Haywood J, Dawson PA.

Atherosclerosis. 2013 Aug;229(2):374-80. doi: 10.1016/j.atherosclerosis.2013.05.017. Epub 2013 May 28.

6.

Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine.

Kim I, Ahn SH, Inagaki T, Choi M, Ito S, Guo GL, Kliewer SA, Gonzalez FJ.

J Lipid Res. 2007 Dec;48(12):2664-72. Epub 2007 Aug 24.

7.

Administration of ampicillin elevates hepatic primary bile acid synthesis through suppression of ileal fibroblast growth factor 15 expression.

Miyata M, Takamatsu Y, Kuribayashi H, Yamazoe Y.

J Pharmacol Exp Ther. 2009 Dec;331(3):1079-85. doi: 10.1124/jpet.109.160093. Epub 2009 Sep 18.

8.

Nuclear receptor-mediated repression of human cholesterol 7alpha-hydroxylase gene transcription by bile acids.

Chen W, Owsley E, Yang Y, Stroup D, Chiang JY.

J Lipid Res. 2001 Sep;42(9):1402-12.

9.

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis.

Inagaki T, Choi M, Moschetta A, Peng L, Cummins CL, McDonald JG, Luo G, Jones SA, Goodwin B, Richardson JA, Gerard RD, Repa JJ, Mangelsdorf DJ, Kliewer SA.

Cell Metab. 2005 Oct;2(4):217-25.

10.

Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism.

Lan T, Rao A, Haywood J, Kock ND, Dawson PA.

J Hepatol. 2012 Aug;57(2):359-65. doi: 10.1016/j.jhep.2012.03.025. Epub 2012 Apr 25.

11.

Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha.

Duez H, van der Veen JN, Duhem C, Pourcet B, Touvier T, Fontaine C, Derudas B, Baugé E, Havinga R, Bloks VW, Wolters H, van der Sluijs FH, Vennström B, Kuipers F, Staels B.

Gastroenterology. 2008 Aug;135(2):689-98. doi: 10.1053/j.gastro.2008.05.035. Epub 2008 May 15.

PMID:
18565334
12.

1alpha,25-Dihydroxyvitamin D(3) triggered vitamin D receptor and farnesoid X receptor-like effects in rat intestine and liver in vivo.

Chow EC, Maeng HJ, Liu S, Khan AA, Groothuis GM, Pang KS.

Biopharm Drug Dispos. 2009 Nov;30(8):457-75. doi: 10.1002/bdd.682.

PMID:
19753549
13.

Hepatic overexpression of Abcb11 in mice promotes the conservation of bile acids within the enterohepatic circulation.

Henkel AS, Gooijert KE, Havinga R, Boverhof R, Green RM, Verkade HJ.

Am J Physiol Gastrointest Liver Physiol. 2013 Jan 15;304(2):G221-6. doi: 10.1152/ajpgi.00322.2012. Epub 2012 Nov 8.

14.

Inhibition of ileal bile acid transport lowers plasma cholesterol levels by inactivating hepatic farnesoid X receptor and stimulating cholesterol 7 alpha-hydroxylase.

Li H, Xu G, Shang Q, Pan L, Shefer S, Batta AK, Bollineni J, Tint GS, Keller BT, Salen G.

Metabolism. 2004 Jul;53(7):927-32.

PMID:
15254889
15.

Activation of Constitutive Androstane Receptor (CAR) in Mice Results in Maintained Biliary Excretion of Bile Acids Despite a Marked Decrease of Bile Acids in Liver.

Lickteig AJ, Csanaky IL, Pratt-Hyatt M, Klaassen CD.

Toxicol Sci. 2016 Jun;151(2):403-18. doi: 10.1093/toxsci/kfw054. Epub 2016 Mar 16.

16.

Effects of essential fatty acid deficiency on enterohepatic circulation of bile salts in mice.

Lukovac S, Los EL, Stellaard F, Rings EH, Verkade HJ.

Am J Physiol Gastrointest Liver Physiol. 2009 Sep;297(3):G520-31. doi: 10.1152/ajpgi.00091.2009. Epub 2009 Jul 16.

17.

FGF15/19 protein levels in the portal blood do not reflect changes in the ileal FGF15/19 or hepatic CYP7A1 mRNA levels.

Shang Q, Guo GL, Honda A, Saumoy M, Salen G, Xu G.

J Lipid Res. 2013 Oct;54(10):2606-14. doi: 10.1194/jlr.M034827. Epub 2013 Jul 12.

18.
19.

Liver receptor homolog-1 is critical for adequate up-regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration.

Out C, Hageman J, Bloks VW, Gerrits H, Sollewijn Gelpke MD, Bos T, Havinga R, Smit MJ, Kuipers F, Groen AK.

Hepatology. 2011 Jun;53(6):2075-85. doi: 10.1002/hep.24286.

PMID:
21391220
20.

FGF15/FGFR4 integrates growth factor signaling with hepatic bile acid metabolism and insulin action.

Shin DJ, Osborne TF.

J Biol Chem. 2009 Apr 24;284(17):11110-20. doi: 10.1074/jbc.M808747200. Epub 2009 Feb 23.

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