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Items: 1 to 20 of 120

1.

Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation.

Tang Z, Arjunan P, Lee C, Li Y, Kumar A, Hou X, Wang B, Wardega P, Zhang F, Dong L, Zhang Y, Zhang SZ, Ding H, Fariss RN, Becker KG, Lennartsson J, Nagai N, Cao Y, Li X.

J Exp Med. 2010 Apr 12;207(4):867-80. doi: 10.1084/jem.20091704. Epub 2010 Mar 15.

2.

PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets.

Hou X, Kumar A, Lee C, Wang B, Arjunan P, Dong L, Maminishkis A, Tang Z, Li Y, Zhang F, Zhang SZ, Wardega P, Chakrabarty S, Liu B, Wu Z, Colosi P, Fariss RN, Lennartsson J, Nussenblatt R, Gutkind JS, Cao Y, Li X.

Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12216-21. doi: 10.1073/pnas.1004143107. Epub 2010 Jun 21.

3.

Platelet-derived growth factor-DD targeting arrests pathological angiogenesis by modulating glycogen synthase kinase-3beta phosphorylation.

Kumar A, Hou X, Lee C, Li Y, Maminishkis A, Tang Z, Zhang F, Langer HF, Arjunan P, Dong L, Wu Z, Zhu LY, Wang L, Min W, Colosi P, Chavakis T, Li X.

J Biol Chem. 2010 May 14;285(20):15500-10. doi: 10.1074/jbc.M110.113787. Epub 2010 Mar 15.

4.

Platelet-derived growth factor CC-mediated neuroprotection against HIV Tat involves TRPC-mediated inactivation of GSK 3beta.

Peng F, Yao H, Akturk HK, Buch S.

PLoS One. 2012;7(10):e47572. doi: 10.1371/journal.pone.0047572. Epub 2012 Oct 15.

5.

Angiogenesis stimulated by PDGF-CC, a novel member in the PDGF family, involves activation of PDGFR-alphaalpha and -alphabeta receptors.

Cao R, Bråkenhielm E, Li X, Pietras K, Widenfalk J, Ostman A, Eriksson U, Cao Y.

FASEB J. 2002 Oct;16(12):1575-83.

PMID:
12374780
7.

Vasoprotective effect of PDGF-CC mediated by HMOX1 rescues retinal degeneration.

He C, Zhao C, Kumar A, Lee C, Chen M, Huang L, Wang J, Ren X, Jiang Y, Chen W, Wang B, Gao Z, Zhong Z, Huang Z, Zhang F, Huang B, Ding H, Ju R, Tang Z, Liu Y, Cao Y, Li X, Liu X.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14806-11. doi: 10.1073/pnas.1404140111. Epub 2014 Sep 29.

8.

PDGF- and insulin/IGF-1-specific distinct modes of class IA PI 3-kinase activation in normal rat retinas and RGC-5 retinal ganglion cells.

Biswas SK, Zhao Y, Nagalingam A, Gardner TW, Sandirasegarane L.

Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3687-98. doi: 10.1167/iovs.07-1455. Epub 2008 Apr 17.

PMID:
18421086
9.

PDGF-C and -D induced proliferation/migration of human RPE is abolished by inflammatory cytokines.

Li R, Maminishkis A, Wang FE, Miller SS.

Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5722-32.

PMID:
18055825
10.

PDGF-CC induces tissue factor expression: role of PDGF receptor alpha/beta.

Gebhard C, Akhmedov A, Mocharla P, Angstenberger J, Sahbai S, Camici GG, Lüscher TF, Tanner FC.

Basic Res Cardiol. 2010 May;105(3):349-56. doi: 10.1007/s00395-009-0060-0. Epub 2009 Oct 1.

PMID:
19795151
11.

Neuroprotective effects of PDGF against oxidative stress and the signaling pathway involved.

Zheng L, Ishii Y, Tokunaga A, Hamashima T, Shen J, Zhao QL, Ishizawa S, Fujimori T, Nabeshima Y, Mori H, Kondo T, Sasahara M.

J Neurosci Res. 2010 May 1;88(6):1273-84. doi: 10.1002/jnr.22302.

PMID:
19998489
12.

Platelet-derived growth factor (PDGF)-C inhibits neuroretinal apoptosis in a murine model of focal retinal degeneration.

Wang Y, Abu-Asab MS, Yu CR, Tang Z, Shen D, Tuo J, Li X, Chan CC.

Lab Invest. 2014 Jun;94(6):674-82. doi: 10.1038/labinvest.2014.60. Epub 2014 Apr 7.

13.

The chemokine stromal cell-derived factor-1 promotes the survival of embryonic retinal ganglion cells.

Chalasani SH, Baribaud F, Coughlan CM, Sunshine MJ, Lee VM, Doms RW, Littman DR, Raper JA.

J Neurosci. 2003 Jun 1;23(11):4601-12.

14.

Glycogen synthase kinase 3beta (GSK3beta) mediates 6-hydroxydopamine-induced neuronal death.

Chen G, Bower KA, Ma C, Fang S, Thiele CJ, Luo J.

FASEB J. 2004 Jul;18(10):1162-4. Epub 2004 May 7.

PMID:
15132987
15.

Sources of PDGF expression in murine retina and the effect of short-term diabetes.

Cox OT, Simpson DA, Stitt AW, Gardiner TA.

Mol Vis. 2003 Dec 10;9:665-72.

16.

Immature neurons from CNS stem cells proliferate in response to platelet-derived growth factor.

Erlandsson A, Enarsson M, Forsberg-Nilsson K.

J Neurosci. 2001 May 15;21(10):3483-91.

17.

Platelet-derived growth factor C promotes revascularization in ischemic limbs of diabetic mice.

Moriya J, Wu X, Zavala-Solorio J, Ross J, Liang XH, Ferrara N.

J Vasc Surg. 2014 May;59(5):1402-9.e1-4. doi: 10.1016/j.jvs.2013.04.053. Epub 2013 Jul 13.

18.

Platelet-derived growth factor C (PDGF-C), a novel growth factor that binds to PDGF alpha and beta receptor.

Gilbertson DG, Duff ME, West JW, Kelly JD, Sheppard PO, Hofstrand PD, Gao Z, Shoemaker K, Bukowski TR, Moore M, Feldhaus AL, Humes JM, Palmer TE, Hart CE.

J Biol Chem. 2001 Jul 20;276(29):27406-14. Epub 2001 Apr 10.

19.

Involvment of cytosolic and mitochondrial GSK-3beta in mitochondrial dysfunction and neuronal cell death of MPTP/MPP-treated neurons.

Petit-Paitel A, Brau F, Cazareth J, Chabry J.

PLoS One. 2009;4(5):e5491. doi: 10.1371/journal.pone.0005491. Epub 2009 May 11.

20.

Platelet-derived growth factor-A-induced retinal gliosis protects against ischemic retinopathy.

Yamada H, Yamada E, Ando A, Seo MS, Esumi N, Okamoto N, Vinores M, LaRochelle W, Zack DJ, Campochiaro PA.

Am J Pathol. 2000 Feb;156(2):477-87.

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