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Items: 1 to 20 of 95


An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells.

Lee WY, Moriarty TJ, Wong CH, Zhou H, Strieter RM, van Rooijen N, Chaconas G, Kubes P.

Nat Immunol. 2010 Apr;11(4):295-302. doi: 10.1038/ni.1855. Epub 2010 Mar 14.


Invariant natural killer T cells act as an extravascular cytotoxic barrier for joint-invading Lyme Borrelia.

Lee WY, Sanz MJ, Wong CH, Hardy PO, Salman-Dilgimen A, Moriarty TJ, Chaconas G, Marques A, Krawetz R, Mody CH, Kubes P.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13936-41. doi: 10.1073/pnas.1404769111. Epub 2014 Sep 9.


Local production of IFN-gamma by invariant NKT cells modulates acute Lyme carditis.

Olson CM Jr, Bates TC, Izadi H, Radolf JD, Huber SA, Boyson JE, Anguita J.

J Immunol. 2009 Mar 15;182(6):3728-34. doi: 10.4049/jimmunol.0804111.


NKT cells prevent chronic joint inflammation after infection with Borrelia burgdorferi.

Tupin E, Benhnia MR, Kinjo Y, Patsey R, Lena CJ, Haller MC, Caimano MJ, Imamura M, Wong CH, Crotty S, Radolf JD, Sellati TJ, Kronenberg M.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19863-8. doi: 10.1073/pnas.0810519105. Epub 2008 Dec 5.


Cross-activating invariant NKT cells and kupffer cells suppress cholestatic liver injury in a mouse model of biliary obstruction.

Duwaerts CC, Sun EP, Cheng CW, van Rooijen N, Gregory SH.

PLoS One. 2013 Nov 15;8(11):e79702. doi: 10.1371/journal.pone.0079702. eCollection 2013.


Invariant NKT cell development requires a full complement of functional CD3 zeta immunoreceptor tyrosine-based activation motifs.

Becker AM, Blevins JS, Tomson FL, Eitson JL, Medeiros JJ, Yarovinsky F, Norgard MV, van Oers NS.

J Immunol. 2010 Jun 15;184(12):6822-32. doi: 10.4049/jimmunol.0902058. Epub 2010 May 14.


Stimulatory lipids accumulate in the mouse liver within 30 min of contact sensitization to facilitate the activation of Naïve iNKT cells in a CD1d-dependent fashion.

Dey N, Szczepanik M, Lau K, Majewska-Szczepanik M, Askenase PW.

Scand J Immunol. 2011 Jul;74(1):52-61. doi: 10.1111/j.1365-3083.2011.02540.x.


Turned on by danger: activation of CD1d-restricted invariant natural killer T cells.

Lawson V.

Immunology. 2012 Sep;137(1):20-7. doi: 10.1111/j.1365-2567.2012.03612.x. Review.


A single amino acid defines cross-species reactivity of tree shrew (Tupaia belangeri) CD1d to human invariant natural killer T (iNKT) cells.

Zhang P, Li D, Stewart-Jones G, Shao X, Zhang Y, Chen Q, Li Y, He YW, Xu XN, Zhang HT.

Immunology. 2009 Dec;128(4):500-10. doi: 10.1111/j.1365-2567.2009.03133.x. Epub 2009 Jun 5.


Hiding lipid presentation: viral interference with CD1d-restricted invariant natural killer T (iNKT) cell activation.

Horst D, Geerdink RJ, Gram AM, Stoppelenburg AJ, Ressing ME.

Viruses. 2012 Oct 23;4(10):2379-99. doi: 10.3390/v4102379. Review.


Immunity, tolerance and autoimmunity in the liver: A comprehensive review.

Doherty DG.

J Autoimmun. 2016 Jan;66:60-75. doi: 10.1016/j.jaut.2015.08.020. Epub 2015 Sep 7. Review.


Leishmania donovani-induced expression of signal regulatory protein alpha on Kupffer cells enhances hepatic invariant NKT-cell activation.

Beattie L, Svensson M, Bune A, Brown N, Maroof A, Zubairi S, Smith KR, Kaye PM.

Eur J Immunol. 2010 Jan;40(1):117-23. doi: 10.1002/eji.200939863.


iNKT Cells Orchestrate a Switch from Inflammation to Resolution of Sterile Liver Injury.

Liew PX, Lee WY, Kubes P.

Immunity. 2017 Oct 17;47(4):752-765.e5. doi: 10.1016/j.immuni.2017.09.016.


Uptake and killing of Lyme disease and relapsing fever borreliae in the perfused rat liver and by isolated Kupffer cells.

Sambri V, Aldini R, Massaria F, Montagnani M, Casanova S, Cevenini R.

Infect Immun. 1996 May;64(5):1858-61.


The tumor antigen N-glycolyl-GM3 is a human CD1d ligand capable of mediating B cell and natural killer T cell interaction.

Gentilini MV, Pérez ME, Fernández PM, Fainboim L, Arana E.

Cancer Immunol Immunother. 2016 May;65(5):551-62. doi: 10.1007/s00262-016-1812-y. Epub 2016 Mar 11.


Macrophage p38 mitogen-activated protein kinase activity regulates invariant natural killer T-cell responses during Borrelia burgdorferi infection.

Hawley K, Navasa N, Olson CM Jr, Bates TC, Garg R, Hedrick MN, Conze D, Rincón M, Anguita J.

J Infect Dis. 2012 Jul 15;206(2):283-91. doi: 10.1093/infdis/jis332. Epub 2012 May 2.


The Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode.

Li Y, Girardi E, Wang J, Yu ED, Painter GF, Kronenberg M, Zajonc DM.

J Exp Med. 2010 Oct 25;207(11):2383-93. doi: 10.1084/jem.20101335. Epub 2010 Oct 4.


Invariant NKT cells promote alcohol-induced steatohepatitis through interleukin-1β in mice.

Cui K, Yan G, Xu C, Chen Y, Wang J, Zhou R, Bai L, Lian Z, Wei H, Sun R, Tian Z.

J Hepatol. 2015 Jun;62(6):1311-8. doi: 10.1016/j.jhep.2014.12.027. Epub 2015 Jan 10.


A pivotal role for antigen-presenting cells overexpressing SOCS3 in controlling invariant NKT cell responses during collagen-induced arthritis.

Veenbergen S, Bennink MB, Affandi AJ, Bessis N, Biton J, Arntz OJ, van den Berg WB, van de Loo FA.

Ann Rheum Dis. 2011 Dec;70(12):2167-75. doi: 10.1136/ard.2011.154815. Epub 2011 Aug 27.


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