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Items: 1 to 20 of 204

1.

Exendin-4 prevents c-Jun N-terminal protein kinase activation by tumor necrosis factor-alpha (TNFalpha) and inhibits TNFalpha-induced apoptosis in insulin-secreting cells.

Natalicchio A, De Stefano F, Orlando MR, Melchiorre M, Leonardini A, Cignarelli A, Labarbuta R, Marchetti P, Perrini S, Laviola L, Giorgino F.

Endocrinology. 2010 May;151(5):2019-29. doi: 10.1210/en.2009-1166.

PMID:
20219981
2.

Exendin-4 protects pancreatic beta cells from palmitate-induced apoptosis by interfering with GPR40 and the MKK4/7 stress kinase signalling pathway.

Natalicchio A, Labarbuta R, Tortosa F, Biondi G, Marrano N, Peschechera A, Carchia E, Orlando MR, Leonardini A, Cignarelli A, Marchetti P, Perrini S, Laviola L, Giorgino F.

Diabetologia. 2013 Nov;56(11):2456-66. doi: 10.1007/s00125-013-3028-4.

PMID:
23995397
4.

Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway.

Ferdaoussi M, Abdelli S, Yang JY, Cornu M, Niederhauser G, Favre D, Widmann C, Regazzi R, Thorens B, Waeber G, Abderrahmani A.

Diabetes. 2008 May;57(5):1205-15. doi: 10.2337/db07-1214.

5.

Exendin-4, a glucagon-like peptide-1 receptor agonist, inhibits cell apoptosis induced by lipotoxicity in pancreatic β-cell line.

Wei Q, Sun YQ, Zhang J.

Peptides. 2012 Sep;37(1):18-24. doi: 10.1016/j.peptides.2012.06.018.

PMID:
22776329
6.

Repression of sterol regulatory element-binding protein 1-c is involved in the protective effects of exendin-4 in pancreatic β-cell line.

Hong SW, Lee J, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY.

Mol Cell Endocrinol. 2012 Oct 15;362(1-2):242-52. doi: 10.1016/j.mce.2012.07.004.

PMID:
22820130
7.

C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts.

Strle K, Broussard SR, McCusker RH, Shen WH, LeCleir JM, Johnson RW, Freund GG, Dantzer R, Kelley KW.

Endocrinology. 2006 Sep;147(9):4363-73.

PMID:
16777978
8.

Effect of PANDER in βTC6-cell lipoapoptosis and the protective role of exendin-4.

Xiang JN, Chen DL, Yang LY.

Biochem Biophys Res Commun. 2012 May 18;421(4):701-6. doi: 10.1016/j.bbrc.2012.04.065.

PMID:
22542939
9.

Oncrasin targets the JNK-NF-κB axis to sensitize glioma cells to TNFα-induced apoptosis.

Gupta P, Dixit D, Sen E.

Carcinogenesis. 2013 Feb;34(2):388-96. doi: 10.1093/carcin/bgs352.

PMID:
23125226
10.
11.

Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells.

Simon-Szabó L, Kokas M, Mandl J, Kéri G, Csala M.

PLoS One. 2014 Jun 4;9(6):e97868. doi: 10.1371/journal.pone.0097868.

12.

Inhibition of c-jun N terminal kinase (JNK) improves functional beta cell mass in human islets and leads to AKT and glycogen synthase kinase-3 (GSK-3) phosphorylation.

Fornoni A, Pileggi A, Molano RD, Sanabria NY, Tejada T, Gonzalez-Quintana J, Ichii H, Inverardi L, Ricordi C, Pastori RL.

Diabetologia. 2008 Feb;51(2):298-308.

PMID:
18066521
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17.

Exendin-4 protects pancreatic beta cells from the cytotoxic effect of rapamycin by inhibiting JNK and p38 phosphorylation.

Kawasaki Y, Harashima S, Sasaki M, Mukai E, Nakamura Y, Harada N, Toyoda K, Hamasaki A, Yamane S, Yamada C, Yamada Y, Seino Y, Inagaki N.

Horm Metab Res. 2010 May;42(5):311-7. doi: 10.1055/s-0030-1249035.

PMID:
20213584
18.

Effects of paeoniflorin on tumor necrosis factor-α-induced insulin resistance and changes of adipokines in 3T3-L1 adipocytes.

Kong P, Chi R, Zhang L, Wang N, Lu Y.

Fitoterapia. 2013 Dec;91:44-50. doi: 10.1016/j.fitote.2013.08.010.

PMID:
23978582
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