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Vitamin D controls T cell antigen receptor signaling and activation of human T cells.

von Essen MR, Kongsbak M, Schjerling P, Olgaard K, Odum N, Geisler C.

Nat Immunol. 2010 Apr;11(4):344-9. doi: 10.1038/ni.1851. Epub 2010 Mar 7.


1,25(OH)2D3 induces regulatory T cell differentiation by influencing the VDR/PLC-γ1/TGF-β1/pathway.

Zhou Q, Qin S, Zhang J, Zhon L, Pen Z, Xing T.

Mol Immunol. 2017 Nov;91:156-164. doi: 10.1016/j.molimm.2017.09.006. Epub 2017 Sep 17.


Stromal cell-derived factor-1 signaling via the CXCR4-TCR heterodimer requires phospholipase C-β3 and phospholipase C-γ1 for distinct cellular responses.

Kremer KN, Clift IC, Miamen AG, Bamidele AO, Qian NX, Humphreys TD, Hedin KE.

J Immunol. 2011 Aug 1;187(3):1440-7. doi: 10.4049/jimmunol.1100820. Epub 2011 Jun 24.


Control of T cell activation by vitamin D.

Smolders J, Thewissen M, Damoiseaux J.

Nat Immunol. 2011 Jan;12(1):3; author reply 3-4. doi: 10.1038/ni0111-3a. No abstract available.


Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation.

Williams BL, Irvin BJ, Sutor SL, Chini CC, Yacyshyn E, Bubeck Wardenburg J, Dalton M, Chan AC, Abraham RT.

EMBO J. 1999 Apr 1;18(7):1832-44.


TRAIL-receptor costimulation inhibits proximal TCR signaling and suppresses human T cell activation and proliferation.

Lehnert C, Weiswange M, Jeremias I, Bayer C, Grunert M, Debatin KM, Strauss G.

J Immunol. 2014 Oct 15;193(8):4021-31. doi: 10.4049/jimmunol.1303242. Epub 2014 Sep 12.


Activated PLC-γ1 is catalytically induced at LAT but activated PLC-γ1 is localized at both LAT- and TCR-containing complexes.

Cruz-Orcutt N, Vacaflores A, Connolly SF, Bunnell SC, Houtman JC.

Cell Signal. 2014 Apr;26(4):797-805. doi: 10.1016/j.cellsig.2013.12.022. Epub 2014 Jan 8.


Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1.

Katagiri K, Shimonaka M, Kinashi T.

J Biol Chem. 2004 Mar 19;279(12):11875-81. Epub 2003 Dec 31.


CD38 signaling regulates B lymphocyte activation via a phospholipase C (PLC)-gamma 2-independent, protein kinase C, phosphatidylcholine-PLC, and phospholipase D-dependent signaling cascade.

Moreno-García ME, López-Bojórques LN, Zentella A, Humphries LA, Rawlings DJ, Santos-Argumedo L.

J Immunol. 2005 Mar 1;174(5):2687-95.


RasGRP links T-cell receptor signaling to Ras.

Ebinu JO, Stang SL, Teixeira C, Bottorff DA, Hooton J, Blumberg PM, Barry M, Bleakley RC, Ostergaard HL, Stone JC.

Blood. 2000 May 15;95(10):3199-203.


Recruitment of Sprouty1 to immune synapse regulates T cell receptor signaling.

Lee JS, Lee JE, Oh YM, Park JB, Choi H, Choi CY, Kim IH, Lee SH, Choi K.

J Immunol. 2009 Dec 1;183(11):7178-86. doi: 10.4049/jimmunol.0803799. Epub 2009 Nov 13.


Dynamics of proximal signaling events after TCR/CD8-mediated induction of proliferation or apoptosis in mature CD8+ T cells.

Wang X, Simeoni L, Lindquist JA, Saez-Rodriguez J, Ambach A, Gilles ED, Kliche S, Schraven B.

J Immunol. 2008 May 15;180(10):6703-12.


The role of the LAT-PLC-gamma1 interaction in T regulatory cell function.

Chuck MI, Zhu M, Shen S, Zhang W.

J Immunol. 2010 Mar 1;184(5):2476-86. doi: 10.4049/jimmunol.0902876. Epub 2010 Feb 3.


T cell receptor-induced activation of phospholipase C-gamma1 depends on a sequence-independent function of the P-I region of SLP-76.

Gonen R, Beach D, Ainey C, Yablonski D.

J Biol Chem. 2005 Mar 4;280(9):8364-70. Epub 2004 Dec 28.


Selective phosphorylation of the Dlg1AB variant is critical for TCR-induced p38 activation and induction of proinflammatory cytokines in CD8+ T cells.

Crocetti J, Silva O, Humphries LA, Tibbs MD, Miceli MC.

J Immunol. 2014 Sep 15;193(6):2651-60. doi: 10.4049/jimmunol.1401196. Epub 2014 Aug 6.


Polyomavirus middle T antigen as a probe for T cell antigen receptor-coupled signaling pathways.

Kennedy AP, Sekulić A, Irvin BJ, Nilson AE, Dilworth SM, Abraham RT.

J Biol Chem. 1998 May 8;273(19):11505-13.

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