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Items: 1 to 20 of 102

1.
2.

Evaluation of 5-hydroxytryptophol and other endogenous serotonin (5-hydroxytryptamine) analogs as substrates for UDP-glucuronosyltransferase 1A6.

Krishnaswamy S, Hao Q, Von Moltke LL, Greenblatt DJ, Court MH.

Drug Metab Dispos. 2004 Aug;32(8):862-9.

3.

Validation of serotonin (5-hydroxtryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6.

Krishnaswamy S, Duan SX, Von Moltke LL, Greenblatt DJ, Court MH.

Drug Metab Dispos. 2003 Jan;31(1):133-9.

4.

Inhibition of paracetamol glucuronidation by tyrosine kinase inhibitors.

Liu Y, Ramírez J, Ratain MJ.

Br J Clin Pharmacol. 2011 Jun;71(6):917-20. doi: 10.1111/j.1365-2125.2011.03911.x.

5.

Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms.

Court MH, Duan SX, von Moltke LL, Greenblatt DJ, Patten CJ, Miners JO, Mackenzie PI.

J Pharmacol Exp Ther. 2001 Dec;299(3):998-1006.

6.

Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.

Fujiwara R, Nakajima M, Yamanaka H, Katoh M, Yokoi T.

Drug Metab Dispos. 2008 Feb;36(2):361-7. Epub 2007 Nov 12.

7.

Interpretation of the effects of protein kinase C inhibitors on human UDP-glucuronosyltransferase 1A (UGT1A) proteins in cellulo.

Abe Y, Fujiwara R, Oda S, Yokoi T, Nakajima M.

Drug Metab Pharmacokinet. 2011 Jun;26(3):256-65. doi: 10.2133/dmpk.DMPK-10-RG-121. Epub 2011 Feb 8.

8.
9.

Activation of glucuronidation through reduction of a disulfide bond in rat UDP-glucuronosyltransferase 1A6.

Ikushiro S, Emi Y, Iyanagi T.

Biochemistry. 2002 Oct 22;41(42):12813-20.

PMID:
12379124
10.

Characterization of niflumic acid as a selective inhibitor of human liver microsomal UDP-glucuronosyltransferase 1A9: application to the reaction phenotyping of acetaminophen glucuronidation.

Miners JO, Bowalgaha K, Elliot DJ, Baranczewski P, Knights KM.

Drug Metab Dispos. 2011 Apr;39(4):644-52. doi: 10.1124/dmd.110.037036. Epub 2011 Jan 18.

11.

Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A6 enzymes.

Hanioka N, Takeda Y, Jinno H, Tanaka-Kagawa T, Naito S, Koeda A, Shimizu T, Nomura M, Narimatsu S.

Chem Biol Interact. 2006 Dec 1;164(1-2):136-45. Epub 2006 Oct 9.

PMID:
17027947
12.

Glucuronidation of etoposide in human liver microsomes is specifically catalyzed by UDP-glucuronosyltransferase 1A1.

Watanabe Y, Nakajima M, Ohashi N, Kume T, Yokoi T.

Drug Metab Dispos. 2003 May;31(5):589-95.

13.
14.

Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.

Ma L, Sun J, Peng Y, Zhang R, Shao F, Hu X, Zhu J, Wang X, Cheng X, Zhu Y, Wan P, Feng D, Wu H, Wang G.

Drug Metab Dispos. 2012 Apr;40(4):734-41. doi: 10.1124/dmd.111.043356. Epub 2012 Jan 11.

15.

Identification of human UDP-glucuronosyltransferases involved in N-carbamoyl glucuronidation of lorcaserin.

Sadeque AJ, Usmani KA, Palamar S, Cerny MA, Chen WG.

Drug Metab Dispos. 2012 Apr;40(4):772-8. doi: 10.1124/dmd.111.043448. Epub 2012 Jan 18.

16.

Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4.

Aprile S, Del Grosso E, Grosa G.

Drug Metab Dispos. 2010 Jul;38(7):1141-6. doi: 10.1124/dmd.109.031435. Epub 2010 Apr 7.

17.

The major chemical-detoxifying system of UDP-glucuronosyltransferases requires regulated phosphorylation supported by protein kinase C.

Basu NK, Kole L, Basu M, Chakraborty K, Mitra PS, Owens IS.

J Biol Chem. 2008 Aug 22;283(34):23048-61. doi: 10.1074/jbc.M800032200. Epub 2008 Jun 13.

18.

The effect of valproic acid on drug and steroid glucuronidation by expressed human UDP-glucuronosyltransferases.

Ethell BT, Anderson GD, Burchell B.

Biochem Pharmacol. 2003 May 1;65(9):1441-9.

PMID:
12732356
19.

Inhibitory effects of commonly used herbal extracts on UDP-glucuronosyltransferase 1A4, 1A6, and 1A9 enzyme activities.

Mohamed ME, Frye RF.

Drug Metab Dispos. 2011 Sep;39(9):1522-8. doi: 10.1124/dmd.111.039602. Epub 2011 Jun 1.

20.

Imipramine N-glucuronidation in human liver microsomes: biphasic kinetics and characterization of UDP-glucuronosyltransferase isoforms.

Nakajima M, Tanaka E, Kobayashi T, Ohashi N, Kume T, Yokoi T.

Drug Metab Dispos. 2002 Jun;30(6):636-42.

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